Gene Information

Name : hemC (TTC1638)
Accession : YP_005607.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1557999 - 1558904 bp
Length : 906 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGCGTCGTCGTGGTGGGAACCCGGGGGAGCGCCCTGGCCCTGGCCCAGACCCGCTTCGTGGTGGAGAGGCTCAAGGA
GACCTGGCCCGAGACGGAGTTCAAGATCCGCACGATTAAGACCCGGGGGGACCAGGGGGCGAGCCCGAGGGAGGAGGCCA
TCTTCGTCAAGGAGATCCAGGAGGCCCTGCTCTCCCGGGAGATTGACATCGCCGTTCACTCCCTCAAGGACCTGCCCACC
GAGTCGCCCCGGGGGCTCAAGATCGCCTCCGTGCCCCGGCGGCAGGACCCCCGGGACGTCTTCCTGGGCAAGGCGGCCAA
GCGCCTCAAGGACCTCCCCCCGGGGGCGGTGGTGGGGACGAGCTCCGTGCGCCGCAAGGCCCAGATCCTCGCCCTGAGGC
CGGACCTCGTGGTGCGGGACCTCCGGGGCAACGTGGACACCCGGCTCGCCGCTTTGGGCAACGGGGAGTACGACGGCATC
GTCCTCGCGGCGGCGGGGCTCATCCGCCTGGACCTCAGGAACCGCATTGACGAGTTCCTGGACCCCGGCGAGGTGCTCCC
CGCCCCCGGCCAGGGGGCCTTGGCCCTGGAGGTGCGGGAAGGGGACGACCTGGCCGAGGAGCTCTGCTACGCCCTGCACC
ACCCCCCCTCCTACCACCGGGTCCGGGCGGAGCGGGCTTTCCTTAGGGGCCTTGGGGCCGGGTGCCTGGCCCCCGTGGGG
GCCCTCGCCCACGTGGAGGAGGACGGGACGCTGCGGCTTGAGGGGGTCCTCCTCACCCCGGACGGGAAGAGCTTCATCCG
GGCGGAGATTGAGGGGGATGTTTCCGAGGCCGAGGAACTGGGGCTGGACCTGGCCCGGGACGTCCTGGAGCAGGGCGGGC
GGGAGATCCTCGCCCAAATCCGATAG

Protein sequence :
MRVVVVGTRGSALALAQTRFVVERLKETWPETEFKIRTIKTRGDQGASPREEAIFVKEIQEALLSREIDIAVHSLKDLPT
ESPRGLKIASVPRRQDPRDVFLGKAAKRLKDLPPGAVVGTSSVRRKAQILALRPDLVVRDLRGNVDTRLAALGNGEYDGI
VLAAAGLIRLDLRNRIDEFLDPGEVLPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAERAFLRGLGAGCLAPVG
ALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVSEAEELGLDLARDVLEQGGREILAQIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-49 44
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-49 44