Gene Information

Name : TTC1611 (TTC1611)
Accession : YP_005580.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1527077 - 1528501 bp
Length : 1425 bp
Strand : +
Note : -

DNA sequence : 
ATGCCGCCTTTTAAGCGCACCAAGATCGTGGCCACCCTGGGGCCGGCCACGGACGACAAGGAGGTGATCCGCGCCCTGGC
GGAGGCCGGGGCCGACGTCTTCCGCCTGAACTTCAGCCACGGCGCCCCCGAGGACCACAGGCGCCGGGTGGGCTGGGTGC
GGGAGGTGGCGGAGGAGCTCGGCCGAACCCTGGCCGTCCTCCAGGACCTCCAGGGCCCGAAGATCCGTGTGGGCCGTTTC
CGGGAGGGCCAGGTCCTCCTCCGCCCGGGGCAGAGGTTCGTCCTCACCGCCGAGCCCGTGGAGGGGGACGAGCACCGCGT
TTCCGTGAGCTACAAGGGGCTTCCCGAGGACGTTTCCCCGGGGCAGATCCTCCTTCTGGACGACGGCCGCATCCGGCTCA
AGGTCCTGGAGGTCCGGAGCCCGGAGATCCTCACGGAGGTGGAGGTGGGCGGGGTCCTCTCCAACAACAAGGGGATCAAC
ATCCCCGGGGCGGACCTCTCCATCCCCGCCCTCTCGGAGAAGGATATCCAGGACCTGGCCCTGGGGGCGGAGCTCGGGGT
GGACTGGGTGGCGGTCTCCTTCGTCCGCACGCGGGACGACCTCCTCCTCGCCCGGCACTACCTCTCCCGCTACGGCTCCA
AGGCCAGGCTCATGGCCAAGATCGAGAAGCCCTCGGCCGTGGCCCGGTTTGAGGAGATCCTGGAGGAGGCGGACGGGATC
ATGGTGGCCCGGGGGGACCTCGGGGTGGAGATGCCCCTGGAGGAGGTGCCCATCGTCCAGAAGCGCCTCATCCTCCGGTG
CATCGCCGCCGGGAAGCCGGTGATCACCGCCACCCAGATGCTGGAGTCCATGGTGCAGAACCCGAGCCCCACCCGGGCCG
AGGCCTCGGACGTGGCCAACGCCATCTTTGACGGGACCGACGCGGTGATGCTCTCCGCGGAGACGGCGGCCGGGGCCTAC
CCGGTGGAGGCGGTGGCCATGATGAGCAGGATCGCCAAGGCGGTGGAATCCTCCCCGGAGTTCTTGCAGAAGCTCAACGT
CCTCCGCCCCGCCCCCACCCCCACCACCCAGGACGCCATCGCCCAGGCGGCGGACGACGTGGTGGAGGCGGTGGGGGCAC
GGGCCATCGTGGTCTTCACGGCCACGGGCGGCTCGGCGCGGAGGATCGCCCGCACCCGGCCCCAGGTGCCCATCCTGGCC
CTCACCCCGAACCCCGAGGTGCGGAACCAGCTGGCCTTGGTCTGGGGGGTCTACCCCCATCTCGCCCCCGACCCCCAGGA
CACCGACGACATGGTCCGCATCGCCCTCAGGGAGGTGAAAGCCCTGGGGCTCGCCCAGGTGGGGGACCGGGTGGTCATCG
CCGCCGGGGTTCCCTTCGGGGTCCGGGGGACAACGAACCTCATCCGCGTGGAGCGGGTGGGGTAG

Protein sequence : 
MPPFKRTKIVATLGPATDDKEVIRALAEAGADVFRLNFSHGAPEDHRRRVGWVREVAEELGRTLAVLQDLQGPKIRVGRF
REGQVLLRPGQRFVLTAEPVEGDEHRVSVSYKGLPEDVSPGQILLLDDGRIRLKVLEVRSPEILTEVEVGGVLSNNKGIN
IPGADLSIPALSEKDIQDLALGAELGVDWVAVSFVRTRDDLLLARHYLSRYGSKARLMAKIEKPSAVARFEEILEEADGI
MVARGDLGVEMPLEEVPIVQKRLILRCIAAGKPVITATQMLESMVQNPSPTRAEASDVANAIFDGTDAVMLSAETAAGAY
PVEAVAMMSRIAKAVESSPEFLQKLNVLRPAPTPTTQDAIAQAADDVVEAVGARAIVVFTATGGSARRIARTRPQVPILA
LTPNPEVRNQLALVWGVYPHLAPDPQDTDDMVRIALREVKALGLAQVGDRVVIAAGVPFGVRGTTNLIRVERVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-77 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 45
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TTC1611 YP_005580.1 pyruvate kinase VFG0479 Protein 5e-78 45