Gene Information

Name : clpB (TTC1123)
Accession : YP_005092.1
Strain : Thermus thermophilus HB27
Genome accession: NC_005835
Putative virulence/resistance : Virulence
Product : endopeptidase Clp ATP-binding chain B, clpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1089864 - 1092428 bp
Length : 2565 bp
Strand : -
Note : -

DNA sequence :
ATGAACCTGGAACGCTGGACCCAAGCCGCCCGCGAAGCCCTGGCCCAGGCGCAGGTCCTGGCGCAAAGGATGAAGCACCA
GGCCATAGACCTGCCCCACCTCTGGGCTGTCCTCCTGAAGGACGAGGGGGGCCTCGCCTGGCGCCTCTTGGAGAAGGCGG
GGGCCGACCCCAAGGCCCTTAAAGAGCTCCAGGAGCGGGAGCTTTCCCGCCTGCCCAAGGTGGAAGGGGCCGAGGTGGGC
CAGTACCTCACGAGCCGCCTCTCCGGGGCCTTGAACCGGGCCGAGGCCCTGATGGAGGAGCTCAAGGACCGCTACGTGGC
GGTGGACACCCTGGTCCTGGCCTTGGCGGAGGCCACGCCGGGGCTTCCGGGCCTGGAGGCCCTGAAGGGGGCGCTCAAGG
AACTGAGGGGAGGGAGAACCGTGCAGACGGAACACGCGGAAAGCACCTACAACGCTTTGGAGCAGTACGGCATTGACCTC
ACGCGGCTTGCCGCCGAGGGGAAGCTGGACCCCGTGATCGGCCGGGACGAGGAGATCCGGCGGGTGATCCAGATCCTCCT
CCGGCGCACCAAGAACAACCCGGTGCTCATCGGCGAGCCCGGCGTGGGGAAGACGGCCATCGTGGAGGGCCTGGCCCAGC
GCATCGTCAAGGGGGACGTGCCCGAAGGCCTCAAGGGCAAGCGGATCGTCTCCTTGCAGATGGGCTCCCTCCTCGCCGGG
GCCAAGTACCGGGGCGAGTTTGAGGAGCGCTTGAAGGCGGTGATCCAGGAGGTGGTCCAGTCCCAAGGGGAAGTCATCCT
CTTCATTGACGAGCTCCACACCGTGGTGGGGGCGGGCAAGGCCGAGGGCGCCGTGGACGCGGGCAACATGCTGAAGCCCG
CCCTGGCCCGGGGGGAGCTCAGGCTCATCGGGGCCACCACCCTGGACGAGTACCGGGAGATTGAGAAGGACCCCGCCCTG
GAGCGCCGCTTCCAGCCCGTGTACGTGGACGAGCCCACGGTGGAGGAGACCATCTCTATCCTCCGGGGCCTCAAGGAGAA
GTACGAGGTCCACCACGGGGTGCGCATCTCCGACAGCGCCATCATCGCCGCCGCCACCCTCTCCCACCGGTACATCACGG
AAAGGCGCCTTCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCGGCCCGCCTGCGCATGGCCCTGGAGAGCGCTCCC
GAGGAGATTGACGCCCTGGAGCGCAAGAAGCTCCAGCTGGAGATTGAGCGGGAGGCCCTGAAGAAGGAGAAGGACCCGGA
CTCCCAGGAGCGCCTCAAGGCCATTGAGGCCGAGATCGCCAAGCTCACGGAGGAGATCGCCAAGCTCCGGGCCGAGTGGG
AGAGGGAGCGGGAGATCCTGAGGAAGCTCCGCGAGGCCCAGCACCGCCTGGACGAGGTCAGGCGGGAGATTGAGCTCGCC
GAGCGGCAGTACGACCTGAACCGGGCCGCCGAGCTCCGCTACGGGGAGCTTCCCAAGCTGGAGGCCGAGGTGGAGGCCCT
TTCGGAAAAGCTCCGGGGCGCCCGCTTCGTCCGCCTCGAGGTCACCGAGGAGGACATCGCCGAGATCGTCTCCCGCTGGA
CCGGGATCCCTGTGTCCAAGCTCCTGGAAGGGGAGAGGGAGAAGCTTTTGAGGCTTGAGGAGGAGCTCCACAAGCGGGTG
GTGGGGCAGGACGAGGCCATAAGGGCCGTGGCCGACGCCATCCGCCGGGCGAGGGCCGGCCTAAAGGACCCGAACCGGCC
CATCGGAAGCTTCCTCTTCCTCGGGCCCACGGGGGTGGGGAAGACGGAGCTCGCCAAGACCCTGGCCGCCACCCTCTTTG
ACACCGAGGAGGCCATGATCCGCATTGACATGACGGAGTACATGGAGAAGCACGCCGTCTCCCGCCTCATCGGGGCCCCG
CCCGGCTACGTGGGCTACGAGGAGGGGGGCCAGCTCACCGAGGCGGTGCGGAGGAGGCCCTACTCGGTCATCCTCTTTGA
CGAGATTGAGAAGGCCCACCCCGACGTCTTCAACATCCTCCTCCAGATCCTGGACGACGGCCGCCTCACCGACAGCCACG
GCCGCACCGTGGACTTCCGCAACACCGTCATCATCCTCACCTCCAACCTGGGGAGCCCCTTGATCCTCGAGGGCCTCCAG
AAGGGCTGGCCCTACGAGAGGATCCGGGACGAGGTCTTTAAGGTCTTGCAGCAGCACTTCCGCCCCGAGTTCCTGAACCG
CCTGGACGAGATCGTGGTCTTCCGGCCCCTCACCAAGGAGCAGATCCGCCAGATCGTGGAGATCCAGCTCTCCTACCTCC
GGGCCCGCCTCGCCGAGAAGCGCATCTCCCTGGAGCTCACCGAGGCCGCCAAGGACTTCCTGGCGGAAAGGGGCTACGAC
CCCGTCTTCGGGGCAAGGCCCTTGCGGCGGGTCATCCAGCGGGAGCTGGAGACGCCCCTCGCCCAGAAGATCCTGGCCGG
CGAGGTCAAGGAGGGGGACCGCGTGCAGGTGGACGTGGGGCCCGCGGGCCTCGTGTTTGCCGTCCCCGCCCGGGTGGAGG
CCTGA

Protein sequence :
MNLERWTQAAREALAQAQVLAQRMKHQAIDLPHLWAVLLKDEGGLAWRLLEKAGADPKALKELQERELSRLPKVEGAEVG
QYLTSRLSGALNRAEALMEELKDRYVAVDTLVLALAEATPGLPGLEALKGALKELRGGRTVQTEHAESTYNALEQYGIDL
TRLAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIVSLQMGSLLAG
AKYRGEFEERLKAVIQEVVQSQGEVILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPAL
ERRFQPVYVDEPTVEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAP
EEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIAKLTEEIAKLRAEWEREREILRKLREAQHRLDEVRREIELA
ERQYDLNRAAELRYGELPKLEAEVEALSEKLRGARFVRLEVTEEDIAEIVSRWTGIPVSKLLEGEREKLLRLEEELHKRV
VGQDEAIRAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMIRIDMTEYMEKHAVSRLIGAP
PGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQ
KGWPYERIRDEVFKVLQQHFRPEFLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKRISLELTEAAKDFLAERGYD
PVFGARPLRRVIQRELETPLAQKILAGEVKEGDRVQVDVGPAGLVFAVPARVEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-97 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-99 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-99 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_005092.1 endopeptidase Clp ATP-binding chain B, clpB VFG2084 Protein 9e-98 41