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Name : yscV (YP_pCD49) Accession : NP_995377.1 Strain : Genome accession: NC_005813 Putative virulence/resistance : Virulence Product : putative membrane-bound Yop protein YscV Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG4789 EC number : - Position : 35078 - 37192 bp Length : 2115 bp Strand : + Note : Best Blastp hit =gi|16082722|ref|NP_395168.1| (NC_003131) putative membrane-bound Yop protein (704 aa) [Yersinia pestis], gi|17380420|sp|P31487|LCRD_YERPE Low calcium response locus protein D, gi|11279044|pir||T43591 low calcium response protein D - Yersi DNA sequence : ATGAATCCCCATGATCTTGAGTGGCTAAATCGTATTGGCGAGCGTAAAGATATCATGCTGGCAGTGCTGCTGTTAGCTGT GGTATTCATGATGGTCTTACCACTCCCCCCCCTTGTGTTGGACATTCTGATTGCTGTTAACATGACCATTTCAGTGGTGT TGTTAATGATAGCGATCTATATCAACTCTCCTTTACAATTTTCAGCTTTCCCTGCGGTGCTACTCGTTACCACGTTATTT CGTCTCGCACTTTCAGTTAGCACCACCCGCATGATCCTGCTACAAGCTGATGCGGGGCAGATTGTTTACACCTTTGGTAA TTTCGTCGTTGGCGGTAACCTCATCGTCGGGATTGTCATCTTCCTGATCATCACTATTGTGCAATTTTTAGTGATAACGA AAGGCTCAGAACGTGTAGCAGAAGTTAGTGCCAGATTCTCTCTTGATGCGATGCCGGGTAAACAGATGAGTATCGATGGC GATATGCGAGCCGGGGTGATCGATGTCAATGAAGCGCGTGAGCGACGCGCGACGATAGAAAAAGAAAGCCAAATGTTCGG TTCTATGGACGGCGCCATGAAGTTCGTCAAAGGGGATGCAATAGCCGGCCTCATTATTATCTTTGTCAATATATTAGGCG GCGTCACCATTGGTGTTACCCAAAAAGGATTAGCGGCCGCTGAGGCACTGCAACTCTATTCCATCCTCACTGTCGGGGAT GGGATGGTTTCTCAGGTACCTGCCCTGCTGATAGCTATTACCGCGGGTATTATCGTCACCCGCGTCTCTTCAGAAGATTC ATCAGATCTGGGTAGCGATATTGGCAAACAGGTTGTCGCTCAGCCTAAAGCCATGCTAATTGGTGGCGTACTGCTGTTGC TCTTTGGTCTTATCCCCGGCTTCCCAACAGTCACCTTTCTGATTTTGGCGCTATTGGTAGGCTGTGGTGGTTATATGCTC AGCCGTAAGCAGAGTCGTAATGACGAGGCTAATCAAGACCTGCAATCCATACTGACGAGCGGTTCTGGCGCCCCGGCTGC TCGAACCAAAGCCAAAACAAGTGGGGCAAACAAGGGCCGACTAGGGGAACAAGAAGCATTTGCTATGACGGTTCCCTTGC TGATTGATGTAGATTCAAGCCAACAGGAAGCACTGGAAGCGATAGCACTAAATGATGAGCTGGTTCGAGTGCGCCGTGCT CTTTATCTTGATCTTGGCGTACCTTTCCCTGGGATCCATCTGCGTTTTAATGAGGGGATGGGTGAAGGCGAATATATTAT TTCCTTGCAAGAAGTTCCAGTGGCGCGAGGTGAGCTTAAGGCAGGTTATTTACTCGTGCGTGAATCCGTCAGCCAACTCG AATTACTGGGTATACCCTATGAAAAAGGGGAACATTTGCTACCCGATCAGGAAGCTTTCTGGGTATCGGTTGAATATGAG GAGCGCCTGGAAAAGTCTCAACTGGAATTTTTCTCTCATTCCCAAGTTCTAACCTGGCATCTTTCTCATGTCCTACGTGA ATATGCCGAAGATTTCATTGGTATCCAAGAAACCCGCTATCTGCTCGAACAGATGGAAGGAGGCTATGGCGAATTAATTA AAGAAGTACAAAGAATCGTTCCCTTACAACGAATGACCGAAATATTACAACGATTAGTTGGAGAAGATATTTCTATCCGT AATATGCGATCTATTCTTGAAGCTATGGTGGAATGGGGACAAAAAGAGAAAGACGTCGTTCAACTCACAGAATATATCCG CAGTAGTCTAAAACGTTATATCTGCTACAAATACGCTAATGGCAACAATATATTGCCGGCTTATCTTTTCGATCAAGAAG TAGAAGAAAAAATTCGTAGCGGTGTGCGCCAAACCAGTGCAGGGAGTTATTTGGCATTGGAGCCTGCTGTTACCGAGAGT TTACTTGAACAAGTTCGCAAGACTATTGGCGATCTATCGCAAATCCAGAGTAAACCGGTGCTGATTGTTTCTATGGATAT TCGTCGCTATGTGCGCAAACTGATTGAGAGCGAATACTATGGCTTGCCGGTACTTTCATACCAAGAGCTGACTCAGCAGA TTAATATCCAACCACTTGGACGAATTTGCTTATGA Protein sequence : MNPHDLEWLNRIGERKDIMLAVLLLAVVFMMVLPLPPLVLDILIAVNMTISVVLLMIAIYINSPLQFSAFPAVLLVTTLF RLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLIVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDG DMRAGVIDVNEARERRATIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGLAAAEALQLYSILTVGD GMVSQVPALLIAITAGIIVTRVSSEDSSDLGSDIGKQVVAQPKAMLIGGVLLLLFGLIPGFPTVTFLILALLVGCGGYML SRKQSRNDEANQDLQSILTSGSGAPAARTKAKTSGANKGRLGEQEAFAMTVPLLIDVDSSQQEALEAIALNDELVRVRRA LYLDLGVPFPGIHLRFNEGMGEGEYIISLQEVPVARGELKAGYLLVRESVSQLELLGIPYEKGEHLLPDQEAFWVSVEYE ERLEKSQLEFFSHSQVLTWHLSHVLREYAEDFIGIQETRYLLEQMEGGYGELIKEVQRIVPLQRMTEILQRLVGEDISIR NMRSILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLFDQEVEEKIRSGVRQTSAGSYLALEPAVTES LLEQVRKTIGDLSQIQSKPVLIVSMDIRRYVRKLIESEYYGLPVLSYQELTQQINIQPLGRICL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lssD | AAO18050.1 | LssD | Virulence | TTSS locus | Protein | 0.0 | 82 |
| YPO0266 | YP_002345347.1 | secretion system apparatus protein SsaV | Virulence | Not named | Protein | 2e-104 | 44 |
| hrcV | AAT96256.1 | HrcV | Virulence | S-PAI | Protein | 4e-100 | 44 |
| hrcV | AAT96297.1 | HrcV | Virulence | S-PAI | Protein | 2e-100 | 44 |
| hrcV | AAT96337.1 | HrcV | Virulence | S-PAI | Protein | 8e-101 | 44 |
| escV | AFO66296.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 7e-100 | 43 |
| escV | AFO66414.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 6e-100 | 43 |
| ECs3731 | NP_311758.1 | EivA | Not tested | LIM | Protein | 3e-103 | 43 |
| hrcV | ABA47273.1 | HrcV | Virulence | S-PAI | Protein | 2e-97 | 43 |
| escV | NP_290269.1 | hypothetical protein | Virulence | LEE | Protein | 2e-98 | 42 |
| ECs4569 | NP_312596.1 | hypothetical protein | Virulence | LEE | Protein | 2e-98 | 42 |
| escV | AAC31514.1 | L0035 | Virulence | LEE | Protein | 2e-98 | 42 |
| escV | YP_003236089.1 | putative translocator EscV | Virulence | LEE | Protein | 2e-98 | 42 |
| escV | ACU09459.1 | EscV protein | Virulence | LEE | Protein | 2e-98 | 42 |
| escV | AAC38382.1 | EscV | Virulence | LEE | Protein | 5e-99 | 42 |
| escV | AAL57541.1 | EscV | Virulence | LEE | Protein | 5e-99 | 42 |
| escV | CAI43875.1 | EscV protein | Virulence | LEE | Protein | 5e-99 | 42 |
| unnamed | AAL06368.1 | EscV | Virulence | LEE | Protein | 1e-97 | 42 |
| escV | YP_003232152.1 | T3SS structure protein EscV | Virulence | LEE | Protein | 6e-99 | 42 |
| escV | CAC81861.1 | EscV protein | Virulence | LEE II | Protein | 7e-99 | 42 |
| escV | YP_003223476.1 | translocator EscV | Virulence | LEE | Protein | 6e-99 | 42 |
| escV | AAK26714.1 | EscV | Virulence | LEE | Protein | 5e-99 | 42 |
| invA | YP_217815.1 | invasion protein | Virulence | SPI-1 | Protein | 5e-105 | 42 |
| invA | NP_457290.1 | possible secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 5e-105 | 42 |
| invA | NP_806499.1 | virulence-associated secretory protein | Virulence | SPI-1 | Protein | 5e-105 | 42 |
| invA | NP_461817.1 | needle complex export protein | Virulence | SPI-1 | Protein | 5e-105 | 42 |
| hrcV | NP_636603.1 | protein HrcV | Virulence | Hrp PAI | Protein | 6e-80 | 41 |
| XC_3013 | YP_244081.1 | HrcV protein | Virulence | Hrp PAI | Protein | 6e-80 | 41 |
| invA | AAS66860.1 | InvA | Not tested | SSR-2 | Protein | 7e-97 | 41 |
| ysaV | AAS66840.1 | YsaV | Not tested | SSR-1 | Protein | 2e-96 | 41 |
| hrcV | AAR25631.1 | type III secretion protein HrcV | Not tested | Not named | Protein | 5e-93 | 41 |
| hrcV | AAT96139.1 | HrcV | Virulence | T-PAI | Protein | 7e-95 | 41 |
| hrcV | AAT96193.1 | HrcV | Virulence | T-PAI | Protein | 5e-95 | 41 |
| hrcV | AAB05999.2 | HrcV | Virulence | Hrp PAI | Protein | 1e-100 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG0384 | Protein | 0.0 | 100 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG0198 | Protein | 0.0 | 80 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG0064 | Protein | 2e-178 | 59 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG2126 | Protein | 4e-129 | 46 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG2461 | Protein | 8e-98 | 43 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG0729 | Protein | 3e-99 | 42 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG0813 | Protein | 1e-98 | 42 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG0557 | Protein | 2e-105 | 42 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG1006 | Protein | 3e-98 | 41 |
| yscV | NP_995377.1 | putative membrane-bound Yop protein YscV | VFG1780 | Protein | 1e-94 | 41 |
