Gene Information

Name : phoB (YP_0727)
Accession : NP_992116.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : phosphate regulon transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 786927 - 787646 bp
Length : 720 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 phoB and Yersinia pestis KIM phoB. Contains Response regulator receiver (Interpro|IPR001789, (GO:0006355)). Contains Transcriptional regulatory protein, C terminal (Interpro|IPR001867, (GO:0006355))

DNA sequence : 
GTGACCGCTAACATACTGGCAGGGTTGATGATGGCAAGACGCATACTGGTGGTGGAAGATGAAGCACCAATCCGTGAGAT
GGTGTGCTTTGTGTTGGAGCAAAATGGCTACCAACCGTTAGAAGCCGAAGATTATGACAGCGCGGTAGCTCGCCTGTCGG
AGCCTTTTCCTGATTTAGTGCTGTTAGACTGGATGTTACCCGGCGGCTCGGGTATTCAGTTTATTAAACATATGAAACGT
GAAGCTTTGACCCGGGATATTCCGGTGATGATGCTGACCGCTCGTGGCGAAGAAGAAGATCGTGTGCGCGGTTTGGAAGT
GGGCGCAGATGATTATATTACCAAGCCTTTTTCACCTAAAGAGCTGGTAGCGCGGATCAAAGCGGTAATGCGGCGGATAT
CGCCAATGGCCGTTGAAGAAGTGATTGAAATGCAAGGGTTGAGCCTTGACCCTTCATCTCACAGGGTAATGGCGAATGAT
CAGGCGCTAGATATGGGGCCGACCGAGTTTAAATTATTACACTTCTTTATGACTCATCCCGAGCGTGTTTATAGCCGTGA
ACAGTTGCTTAATTATGTTTGGGGCACTAACGTTTATGTAGAAGATCGTACGGTTGATGTGCATATTCGTCGGTTACGCA
AGGCGCTTGAAACTGATGGTCACGATAAAATGGTACAAACTGTCCGGGGAACTGGATACCGTTTCTCAACGCGCTACTGA

Protein sequence : 
MTANILAGLMMARRILVVEDEAPIREMVCFVLEQNGYQPLEAEDYDSAVARLSEPFPDLVLLDWMLPGGSGIQFIKHMKR
EALTRDIPVMMLTARGEEEDRVRGLEVGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPSSHRVMAND
QALDMGPTEFKLLHFFMTHPERVYSREQLLNYVWGTNVYVEDRTVDVHIRRLRKALETDGHDKMVQTVRGTGYRFSTRY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 6e-34 41
CDB402_0209 YP_005126722.1 two-component system response regulator Not tested Not named Protein 2e-31 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 6e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoB NP_992116.1 phosphate regulon transcriptional regulator HE999704.1.gene2815. Protein 5e-39 44
phoB NP_992116.1 phosphate regulon transcriptional regulator CP001918.1.gene5135. Protein 3e-24 42
phoB NP_992116.1 phosphate regulon transcriptional regulator BAC0596 Protein 2e-33 41
phoB NP_992116.1 phosphate regulon transcriptional regulator CP001138.1.gene2239. Protein 2e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoB NP_992116.1 phosphate regulon transcriptional regulator VFG1563 Protein 3e-34 41
phoB NP_992116.1 phosphate regulon transcriptional regulator VFG1702 Protein 3e-34 41