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Name : clpB1 (YP_0656) Accession : NP_992046.1 Strain : Yersinia pestis 91001 Genome accession: NC_005810 Putative virulence/resistance : Unknown Product : protein disaggregation chaperone Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 701023 - 703617 bp Length : 2595 bp Strand : + Note : highly similar to Yersinia pestis CO92 clpB and Yersinia pestis KIM clpB. Contains Chaperonin clpA/B (Interpro|IPR001270). Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains AAA ATPase (Interpro|IPR003593, (GO:0000 DNA sequence : TTGACCAATATTGGAGGTGTTATGCGTCTGGATCGTCTTACCAGTAAATTCCAGCTTGCCCTCGCCGATGCCCAGTCTTT AGCTCTTGGGCGCGACAACCAGTTTATTGAACCGTTACATTTGATGAGCGCACTGCTTAATCAGGATGGGGGGACGGTTC GCCCTTTATTGACCTCGGCAGGGATTAATGTTGCACGTTTACGTAGCGACATTGAGCAAGCTTTAGGTCGTCTTCCTCAA GTTGAAGGCACCGGCGGTGATGTTCAACCATCAAACGAGCTGGTTCGTGTATTAAATCTTTGCGACAAATTAGCGCAGAA ACGTTCGGATAAGTTTATCTCTTCCGAGCTGTTCGTCCTGGCCGTACTTGAAGATCGTGGCACGTTAACTGACATGTTAA AGGCTGCAGGTGCAACCGTCGCTATAATAGATAAGGCAATTGAAACCATGCGTGGTGGTGACAAAGTCGATGATCAGGGT GCTGAAGATCAGCGCCAGGCGTTGAAAAAATTCACTATCGACCTGACTGAGCGTGCCGAGCAAGGCAAACTCGATCCGGT TATTGGCCGTGATGAAGAAATTCGCCGTACTATTCAGGTATTACAACGTCGAACCAAAAATAACCCAGTGTTGATTGGTG AGCCTGGGGTGGGTAAAACCGCTATTGTGGAAGGTTTGGCGCAACGCATTGTGAACGGCGAAGTGCCAGAAGGCTTGAAG CATAAGCGTGTACTCTCATTAGATATGGGGTCGCTGATTGCCGGTGCCAAATATCGTGGTGAATTTGAAGAGCGTTTGAA AGGCGTACTGAACGACTTATCAAAACAAGAAGGCAGTGTGATCTTGTTTATTGATGAGTTGCATACCATGGTCGGTGCCG GTAAAGGCGATGGGGCGATGGATGCCGGTAACATGCTGAAACCTGCATTAGCGCGAGGTGAGTTACATTGTGTGGGGGCC ACTACCCTCGATGAATACCGTCAATATATAGAGAAAGATGCTGCGCTCGAGCGGCGTTTCCAAAAAGTGTATGTTGCGGA ACCAACGGTAGAAGACACTATCGCTATTTTACGTGGGCTGAAAGAGCGCTACGAACTGCACCATCACGTGCAGATCACTG ACCCAGCTATTGTGGCAGCCGCAACATTGTCACACCGGTATATTTCTGATCGTCAGTTACCGGATAAAGCTATCGACCTC ATTGATGAGGCAGGTTCCAGCATCCGTATGCAAATGGATTCAAAACCCGAATCATTGGATCGTCTAGAGCGCCGGATTAT TCAGCTTAAACTGGAACAGCAGGCCCTAAAAAAAGAGTCAGATGACGCCAGTAAAAAACGGTTGGAAATGCTCAATACTG AGTTAGAGCAAAAAGAGCGTGAATATTCTGAACTGGAAGAAGAGTGGAAAGCAGAAAAAGCTTCACTCACCGGGACTCAG AATATCAAGACGGAGTTGGAACAAGCTAAAATCACCTTAGAACAAGCTCGTCGAGTAGGTGATCTGGCTCGGATGTCAGA ACTTCAGTACGGTACAATCCCTGAGCTGGAAAAACAGCTGGCGGCGGCAACCGCGCTAGAAGGGAAAACCATGAAGTTGC TGCGTAACCGTGTCACAGAAATCGAAGTTGCTGAAGTCCTGGCTCGCTGGACCGGTATCCCGGTATCTCGCATGTTGGAA AGTGAGCGGGATAAGCTGCTACGTATGGAACAGGACTTGCATCAACGAGTCATTGGGCAAGATGAAGCTGTTGAAGCCGT CTCCAACGCTATCCGTCGGAGTCGCGCAGGGTTGTCTGATCCAAACCGACCAATTGGTTCGTTCTTATTCTTAGGGCCAA CGGGGGTTGGTAAAACTGAATTGTGTAAAGCGTTGGCAACGTTCTTGTTCGACAGTGACGATGCCATGGTGCGAATCGAC ATGTCCGAGTTTATGGAGAAACATTCCGTATCGCGGTTGGTCGGTGCACCTCCTGGCTATGTTGGGTATGAAGAAGGTGG CTATCTGACGGAAGCGGTTCGTCGTCGTCCTTATTCTGTGATTTTGCTGGATGAAGTTGAAAAAGCACATCCAGATGTTT TCAACATATTGTTACAGGTATTGGATGATGGTCGTTTGACCGACGGGCAGGGGAGAACTGTCGACTTTCGTAACACGGTA GTCATTATGACCTCTAACCTTGGTTCAGATTTGATTCAGGAACATTTCGGCCAAATGAATTACAGCGAAATGAAGACAGT GGTTATGGATGTTGTTAGTCACCACTTCCGTCCTGAATTTATTAACCGTATAGATGAGGTTGTTGTCTTCCACCCACTTG GTCGGGCGCACTTGGCTTCTATTGCCAACATTCAACTGGAGCGTTTGTATAAACGTCTGGAAGAACGTGGCTATGAAGTG AAGATTACTCAGCCTGCATTGGAATTCTTGGGTGAAGCTGGCTTCGACCCTGTTTATGGGGCGCGGCCATTAAAACGTGC AATTCAGCAGGAAATTGAGAACCCGCTGGCACAGCAGATACTTTCTGGCAAACTAATACCGGGAATCCCCGTGACTTTAG ATGTTGAAAATGGGCATATTATTGCTAAGCAGTAA Protein sequence : MTNIGGVMRLDRLTSKFQLALADAQSLALGRDNQFIEPLHLMSALLNQDGGTVRPLLTSAGINVARLRSDIEQALGRLPQ VEGTGGDVQPSNELVRVLNLCDKLAQKRSDKFISSELFVLAVLEDRGTLTDMLKAAGATVAIIDKAIETMRGGDKVDDQG AEDQRQALKKFTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLK HKRVLSLDMGSLIAGAKYRGEFEERLKGVLNDLSKQEGSVILFIDELHTMVGAGKGDGAMDAGNMLKPALARGELHCVGA TTLDEYRQYIEKDAALERRFQKVYVAEPTVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDL IDEAGSSIRMQMDSKPESLDRLERRIIQLKLEQQALKKESDDASKKRLEMLNTELEQKEREYSELEEEWKAEKASLTGTQ NIKTELEQAKITLEQARRVGDLARMSELQYGTIPELEKQLAAATALEGKTMKLLRNRVTEIEVAEVLARWTGIPVSRMLE SERDKLLRMEQDLHQRVIGQDEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALATFLFDSDDAMVRID MSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTV VIMTSNLGSDLIQEHFGQMNYSEMKTVVMDVVSHHFRPEFINRIDEVVVFHPLGRAHLASIANIQLERLYKRLEERGYEV KITQPALEFLGEAGFDPVYGARPLKRAIQQEIENPLAQQILSGKLIPGIPVTLDVENGHIIAKQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 5e-103 | 43 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 1e-99 | 41 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 2e-99 | 41 |
