Gene Information

Name : flhB1 (YP_0428)
Accession : NP_991822.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaU
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4792
EC number : -
Position : 452121 - 453191 bp
Length : 1071 bp
Strand : +
Note : member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli

DNA sequence :
ATGATGTCCACTGAAAAGAATGAAAAACCCACGCCCAAGCGCCTTAAGGAAGCCAAAGAAAAAGGGCAGGTAGTCAAAAG
TGTTGAGATAACCTCCGGCGTACAGTTGGTGGCGCTGGTTATCTACTTTTTACTGACAGGATATAGCTTGGTCGAGCAGG
CTAAAGCCCTTATCCGCAGTTCAATCATACAATTACAGCAACCACTTACTCTGGCTTTAGCCCGTATCGGTGCCGAGTGC
ATGACGGTATTGATGCATATCGTGGTGGTCTTGGGCGGGGCGCTGATCGTGGTCACCATTATTGCCGGTATTGCTCAGGT
TGGGCCGTTGTTGGCGACCAAAGCGGTGTCGTTTAAAGGTGAGCGAATTAACCCCATTCAAAATGCTAAACAACTTTTCT
CATTGCGCAGCGTGTTTGAGCTGATGAAATCATTATTGAAAGTGGGGGTGCTAACGCTGATTTTTGGTTACTTATTGATG
CAGTATGCGCCCTCTTTTGGTTATTTGACCCACTGTGGCAGTCGCTGTGCTCTCCCGGTATTCTCGACATTAATGGGGTG
GTTATTAGGCTCACTGATTGCCTGCTATCTGGTTTTTTCACTGATGGATTATGCTTTTCAGCGCTACACCATCATGAAAC
AACTGAAAATGTCCCATGATGAGGTCAAGCGGGAGTATAAAGACAGTAATGGGGATCCGCACATTAAGCAGAAGCGGCGG
CAGCTACAGCATGAAGTACAAAGCGGTAGTTTTGCCACTAACGTGCGCCGTTCCACCGCGGTAGTCCGTAACCCGACACA
TTTTGCCGTTTGTCTGATTTATCACCCAGAAGAGACGCCGCTACCGATAGTGATTGAAAAAGGTCATGACGAGCAGGCTG
CATTGATTGTGAGCCTCGCAGAGCAGAGCGGTATCCCTGTGGTAGAAAACATTGCGCTGGCGCGCGCATTACACCGTGAT
GTTGCTTGTGGTGACACCATCCCGGAACAATTCTTCGAGCCAGTTGCTGCGCTCTTACGTATGGCACTGGAGTTGGATTA
TCAGCCATCAAGTGATGATCCACCGCGCTAG

Protein sequence :
MMSTEKNEKPTPKRLKEAKEKGQVVKSVEITSGVQLVALVIYFLLTGYSLVEQAKALIRSSIIQLQQPLTLALARIGAEC
MTVLMHIVVVLGGALIVVTIIAGIAQVGPLLATKAVSFKGERINPIQNAKQLFSLRSVFELMKSLLKVGVLTLIFGYLLM
QYAPSFGYLTHCGSRCALPVFSTLMGWLLGSLIACYLVFSLMDYAFQRYTIMKQLKMSHDEVKREYKDSNGDPHIKQKRR
QLQHEVQSGSFATNVRRSTAVVRNPTHFAVCLIYHPEETPLPIVIEKGHDEQAALIVSLAEQSGIPVVENIALARALHRD
VACGDTIPEQFFEPVAALLRMALELDYQPSSDDPPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0273 YP_002345355.1 secretion system apparatus protein SsaU Virulence Not named Protein 6e-161 100
ssaU YP_216430.1 secretion system apparatus protein SsaU Virulence SPI-2 Protein 9e-71 49
ssaU NP_456106.1 putative type III secretion protein Virulence SPI-2 Protein 7e-72 49
ssaU NP_805093.1 secretion system apparatus protein SsaU Virulence SPI-2 Protein 7e-72 49
ssaU CAA68202.1 secretion system apparatus, SsaU Virulence SPI-2 Protein 9e-72 48
ssaU NP_460387.1 secretion system apparatus protein SsaU Virulence SPI-2 Protein 1e-71 48
escU YP_003223487.1 T3SS structure protein EscU Virulence LEE Protein 4e-62 42
escU AAC38372.1 EscU Virulence LEE Protein 5e-62 42
escU YP_003232141.1 secretion system apparatus protein SsaU Virulence LEE Protein 3e-62 42
escU AAC31525.1 L0046 Virulence LEE Protein 5e-62 42
escU ACU09470.1 secretion system apparatus protein SsaU Virulence LEE Protein 5e-62 42
escU AAK26703.1 EscU Virulence LEE Protein 3e-62 42
escU AAL57530.1 EscU Virulence LEE Protein 3e-62 42
escU YP_003236100.1 T3SS structure protein EscU Virulence LEE Protein 6e-62 42
escU CAI43886.1 EscU protein Virulence LEE Protein 3e-62 42
escU NP_290280.1 secretion system apparatus protein SsaU Virulence LEE Protein 6e-62 42
escU CAC81850.1 EscU protein Virulence LEE II Protein 3e-62 42
ECs4580 NP_312607.1 secretion system apparatus protein SsaU Virulence LEE Protein 6e-62 42
escU AFO66403.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 6e-58 41
escU AFO66307.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 6e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
flhB1 NP_991822.1 secretion system apparatus protein SsaU VFG0522 Protein 5e-72 48
flhB1 NP_991822.1 secretion system apparatus protein SsaU VFG0718 Protein 3e-62 42
flhB1 NP_991822.1 secretion system apparatus protein SsaU VFG0824 Protein 3e-62 42