Gene Information

Name : baeS1 (YP_0409)
Accession : NP_991803.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : two-component sensor/regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0642
EC number : -
Position : 435398 - 438187 bp
Length : 2790 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 YPO0256 and Yersinia pestis KIM y0513. Contains Response regulator receiver (Interpro|IPR001789, (GO:0006355)). Contains ATP-binding region, ATPase-like (Interpro|IPR003594, (GO:0005524)). Contains Histidine kinase,

DNA sequence :
TTGACATTATTAATGGGCGTCACACTAACTGTTATTTGGTTAATATTAATCGCAACAACGGCATTCTTTTCATATGAAAA
TACACGTCAAATATTAATCAATGAGTTAACACATATGGCATCGATGCGGGCGGACTTAAGTAATCACCAGTTTGAAGGAG
CTGAACGTGATGCCGCCTCGTTAATAAGCCGACGAGAAAGCCTCCAGAGCACCTCACCGTTGCCTGAAATATCGATAAAA
CATTATGATAGCTACTATATTCCCTTTAATCTGGATAGCTGTAATATTAACCAACATAAAAATGATCTGTGGATAATTCA
AGCGTATGGCACCGCCGGACAAACTTATTATCTCGACAGTTTTATTATCAAACAAAAAGAGGGGATTGTGTTATTCCCAC
CCCAAAAATCATCGAGTGATTACCTAAATCAACGGCGCAAAGATTTACTTTTGCTCCCCAAATTTCCTACTCACAATAAT
ATCTATTGGGGAGCCCCCACCTATACGCCTCAAGGTGGCTGGCATGTTTCTGTCGCGGTGTGTGATAAAGTGGGCACCTT
AGCTGGCTTCGCCTTAAAACTGAATGATCTCATCGCCTATAATCACCCTGTCGAGCAAAGAGACATTAATTTATTGTTGG
ATAAGAATGGTGAATTATTGCCTATTTCCCAGCAAGCAACATCATCAAATCAACTGCATGAAATTCTTAACCAACTCAAA
AACAGTAAATTACACGATGGCTGGCAGCAAACTCCCGACTATTTGGTATTACGCACCCAATTGAAAGGGCCGGGTTGGCA
GCAATTAGTTATTTATCCGCGAATGGGCTTTGCCTGGGAGGCACTGAAACCCGCCTTATATCAACTCCCTTTCGCTCTGG
CTATTTTACTGTTGCTCACGTCAGTACTGTCACTGCTGCTGCGATATTATCTGGCGATCCCTTTGTGGAATTTCATCAAT
ATCATTGGCGCTACCGGGCCACAGGCAATGGAACCCCGACTTCCCATAAACCGAATAGATGAATTAGGGCATATTGCCCG
CGCTTATAACAACTTACTGGATACGTTGAACGAACAATATGACACCTTAGAAATGAAAGTGAAGGAGCGCACTCTGGCTC
TGGCGGAAGCCAAACGAGCGGCTGAGCAGGCTAACCGCCGTAAAAGCGACCATCTGACCACGATCAGCCATGAAATCCGT
ACACCGCTCAACGGGGCGTTGGGGGCGGTTGAATTATTACAAAATACACCACTGGATGCTGGCCAAATGAGGTTAGCGGA
AACGGCCCACCAATGTTCGTTGTCACTGCTCGCGATCATTAACAACCTGTTAGATTTTTCACGTATTGAATCAGGGCAGA
TGACACTGTCGCTGGAGAAAACGGCCCTACTGCCTTTACTGGATCAGGCGATGTTAACCATTCATAGCCAGGCACTGAGT
AAGTCATTAGCGCTGTCCACGTTTATCAGTGCCAATATCCCGCTGGAACTTGAGCTGGATACACTGCGCTTAAGACAGAT
TCTGGTTAATTTATTAGGTAATGCCGTTAAATTCACACCACAGGGCCGTATTCAACTCAGGGTCAGGCGTCAAAACCAAA
CGCTTTGTTTTACCGTTGAGGACACCGGTTGTGGTATTGACGTGCAACACCAACAAACAATATTCCAACCTTTTATGCAG
ACCAGTGACCATGAACAAGGAACGGGTTTGGGGCTGGCTATCGCAGATAATCTGGCCAAAATGATGGGAGGGCACCTGAC
AGTATTCAGTGAACCGGGTCAAGGTAGCTGTTTTTCATTATGCCTCCCCTTCAATGCAATCACCCCGCCAATGCCTTTTC
ATGGCGAGCTATTCGCACCACAACGCTTACACGCCCAATTATCAGCCTGGGGCATGACCTGCCAGCCAGAATTAGCTAAT
CAGCCATCACGGCACTTTGTGGATAACGCATTGTGTTACTTACCCGGCCGGTTATACGCCAAGCTGAAACAATATCTACA
AGGTGCTGAGACTGAAGCGCTAAAGAGCCTTCCGCTGCAACCTTGGCAGATGCACATTCTATTGGTTGATGACTCCGAAA
CTAATCGCGATATTACCGGAATGATGTTGCAGCAACTGGGGCATCAGGTCACGCGGGCAGACAGTGGCACAACCGCATTG
GCGATTGGCCGCCAACACCGTTTCGATTTAGTGCTAATGGATATTCGAATGCCTGTCCTGGACGGGCTGGCCACCACAGC
ACGCTGGCGTCATGATCCGGCGAACATTGATAGCCACTGCATGATCACCGCCCTGAGCGCCAATGCCAGCCCGGATGAGC
AAATCAAAACCAGTCAGGCGGGGATGAATCACTACCTTTCCAAGCCTGTCACCCTCGGCCAATTGGCTGAAATGTTAGAT
CTGACCGCACAATTCCAGCTTGAGCGTGGGGTCGATCTATCACCACAACTCTCCGAGCCTCAGCCATTACTGGATCTCGC
GGACAGCGCGTTGTCCCTGAAACTTTATCAATCACTGCAAGTATTAATTCAACAGGCCAAAGACGCTATTGAGAACTTGC
CCGTATTATCCCATACGCTTCACACCATAAAAGGCTGTGCCGGGCAAGCTGGGCTAATTGAATTACAAGATGCGGTCATT
CAATTAGAACACGCTCTCGATACTCATGAAACGCTGACACAGCAAGAGATCATTCAACTTGATGAAATAATTCATGTGCT
GCTACAGCCCCCCACTACCTGCGAATCCACGTTTATCATCAGCCAGGGCCAGTCCCTTATGGTTAAATAA

Protein sequence :
MTLLMGVTLTVIWLILIATTAFFSYENTRQILINELTHMASMRADLSNHQFEGAERDAASLISRRESLQSTSPLPEISIK
HYDSYYIPFNLDSCNINQHKNDLWIIQAYGTAGQTYYLDSFIIKQKEGIVLFPPQKSSSDYLNQRRKDLLLLPKFPTHNN
IYWGAPTYTPQGGWHVSVAVCDKVGTLAGFALKLNDLIAYNHPVEQRDINLLLDKNGELLPISQQATSSNQLHEILNQLK
NSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRMGFAWEALKPALYQLPFALAILLLLTSVLSLLLRYYLAIPLWNFIN
IIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLEMKVKERTLALAEAKRAAEQANRRKSDHLTTISHEIR
TPLNGALGAVELLQNTPLDAGQMRLAETAHQCSLSLLAIINNLLDFSRIESGQMTLSLEKTALLPLLDQAMLTIHSQALS
KSLALSTFISANIPLELELDTLRLRQILVNLLGNAVKFTPQGRIQLRVRRQNQTLCFTVEDTGCGIDVQHQQTIFQPFMQ
TSDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCFSLCLPFNAITPPMPFHGELFAPQRLHAQLSAWGMTCQPELAN
QPSRHFVDNALCYLPGRLYAKLKQYLQGAETEALKSLPLQPWQMHILLVDDSETNRDITGMMLQQLGHQVTRADSGTTAL
AIGRQHRFDLVLMDIRMPVLDGLATTARWRHDPANIDSHCMITALSANASPDEQIKTSQAGMNHYLSKPVTLGQLAEMLD
LTAQFQLERGVDLSPQLSEPQPLLDLADSALSLKLYQSLQVLIQQAKDAIENLPVLSHTLHTIKGCAGQAGLIELQDAVI
QLEHALDTHETLTQQEIIQLDEIIHVLLQPPTTCESTFIISQGQSLMVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0256 YP_002345336.1 two-component sensor/regulator Not tested Not named Protein 0.0 99
spiR AAC44299.1 SpiR Virulence SPI-2 Protein 7e-143 46
ssrA NP_456136.1 putative two-component sensor kinase Virulence SPI-2 Protein 2e-150 45
ssrA NP_805063.1 two-component sensor kinase Virulence SPI-2 Protein 6e-151 45
ssrA YP_216400.1 secretion system regulator:sensor component Virulence SPI-2 Protein 5e-151 45
ssrA NP_460357.1 sensor kinase Virulence SPI-2 Protein 5e-150 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
baeS1 NP_991803.1 two-component sensor/regulator VFG0493 Protein 2e-150 44