Gene Information

Name : citB1 (YP_0408)
Accession : NP_991802.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : two-component response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 434753 - 435385 bp
Length : 633 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 YPO0255 and Yersinia pestis KIM y0512. Contains Bacterial regulatory protein, LuxR family (Interpro|IPR000792, (GO:0006355)). Contains Response regulator receiver (Interpro|IPR001789, (GO:0006355))

DNA sequence : 
ATGAATACTAAATTATTGATTGTCGACGATCATGAACTCATTATTCATGGCATCAAGAATATGCTGGCCGCCTATCCGCG
CTACCTGATTGTAGGCCAAGCGGATAATGGACTTGAAGTGTATAACTTGTGCCGCCAAACTGAACCTGACATGGTCATTC
TGGATTTAGGATTACCCGGTATGGATGGCCTTGATGTTATCATTCAGTTGCTTCGCCGTTGGCCAGCCCTGAAGATCCTG
ACGTTAACCGCCCGCAATGAAGAACACTATGCCAGCAGAACATTCAACAGTGGAGCCTTAGGTTATGTGCTGAAGAAAAG
TCCCCAGCAAATCCTGATGGCAGCCATTCAAACCGTCGCAATAGGTAAACGTTATATTGACCCCGCCCTTGATGCCTCTA
TGGTAATAAAACTGACCCAAGGATCCGATAATACGCCCCCGGTTCTGACACCTCGCGAGCGGCAGATATTAAAACTTATC
ACCGAGGGATCGTGTAATCGAGTTATTGCTGCTCAACTTTCTATCAGCCAAAAAACCGTCGAAACACATCGGCTGAATAT
GATGAAAAAATTGGATGTACATAAAGTCGCAGAACTTATTCACTGGTCATACCGATTAGGCTTGAATGTCTAA

Protein sequence : 
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPGMDGLDVIIQLLRRWPALKIL
TLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVAIGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLI
TEGSCNRVIAAQLSISQKTVETHRLNMMKKLDVHKVAELIHWSYRLGLNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0255 YP_002345335.1 two-component response regulator Not tested Not named Protein 7e-89 100
ssrB YP_216399.1 secretion system transcriptonal activator Virulence SPI-2 Protein 6e-41 56
ssrB NP_456137.1 putative two-component response regulator Virulence SPI-2 Protein 5e-41 56
ssrB NP_805062.1 two-component response regulator Virulence SPI-2 Protein 5e-41 56
ssrB NP_460356.1 transcriptional activator Virulence SPI-2 Protein 5e-41 56
ssrB CAB09344.1 SsrB Virulence SPI-2 Protein 1e-35 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
citB1 NP_991802.1 two-component response regulator VFG0492 Protein 2e-41 56
citB1 NP_991802.1 two-component response regulator VFG2440 Protein 1e-25 41