Gene Information

Name : tcaC1 (YP_3866)
Accession : NP_995134.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : insecticidal toxin complex
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4394795 - 4399285 bp
Length : 4491 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 YPO3678 and Yersinia pestis KIM tcaC1 ( residues 1 to 1496 of 1496 are highly similar to residues 21 to 1516 of 1516 from Yersinia pestis KIM tcaC1). Contains Regulator of chromosome condensation, RCC1 (Interpro|IPR0

DNA sequence :
ATGGAAAACAGTAAACAGCAAGTGGCCGTTGCTCCCTTGTCGCTCCCTAAAGGGGGCGGTGCGATTACCGGTATGGGCGA
TAGTTTAGGTCCTATCGGCCCCAGTGGCATGGCAACACTGACGCTGCCTCTGCCGATCTCCGCAGGCCGCGGTTACGCCC
CCTCGCTCACGCTAAGTTACAGTAGCGGCAGTGGTAACGGCCCGTTTGGCCTTGGCTGGCAACTCGGCACCATGGCGATT
CGCCGCCGAACCAACGCCCAAGTGCCACGTTACGATGAGTATGATGAATTTCTGGCTCCCAATGGGGAAGTCATGGTGGT
TGCCGCGGATCCGCAGGGCAGTATCGAACGCACTGAACAGTCACTAAATGGGGAACAATTCAGCGTAATTCGTTACTTAC
CACGTATTGAAGGCAATTTTCATCGCATTGAGTATTGGCGACCCCGGACAAATAACAGCCAGGCACCGTTTTGGTTAGTC
CACAGTTCAGATGGCCAAAAACACTGTTTGGGGTATTCCGCTGCCGCGCGAATTGCCGATCCACTGCACCCTGAGCATAT
TGCTGAATGGCTACTGGAAGAGTCGGTGTCTCTGAGCGGTGAGCATATCGGCTACCAGTATCAGGCAGAAGATGAACAAG
GCATTGATGAGCCTAGTATTTATAAGGCTGAAAAACAAAATCATCCAGCAGCCAGTGCGCAACGCTATCTGAAACGCGTG
GTTTATGGTAATCGCCAAGCGGCGTATGAACTCTATTGTCTGACTCAGCAACCTGCGCCGACAAGCTGGTTATTTAGCCT
GATTTTTGATCACGGCGAATACAGTAATATCGCGGAGCAAGTGCCGGTAATCATAAAAGGAAAATCCTGGAATTTCCGTC
AGGACGCCTTCTCACACTTTAACTATGGCTTTGAAGTGCGTACCCGCCGCTTGTGTCAGCAAGTGTTGATGTACCATAAT
TTGTCAGCACTTAAAGGTGATGAACCCGATGCTCAAGCCACGCTGGTTAGCCGTCTGCGTTTACACTATCAGCACGATGC
TTATGCCACCCAACTGGTCGGTTGCCAACAGTTAGCCCATGAACCCGATGGCACCAAACGTAGCCTGCCACCGCTAGAAT
TTGATTATCAGGATTTTTCCACTCGCGACGCCCTTGGTTGGCAACCACTTACTGATTGGGCTGAATTTAACTATCAGTAC
CAAATGGTGGATCTGAACGGCGAAGGGATGCCGGGGATGTTGTATCAGGACAGCGGTCACTGGATTTATCGCCCACCGGT
TCGCCAACCAGGCACCGCCGACGGCATCACTTTTGGCGCGGCCCAACGGTTACCGAGCCTACCCGCGATGCGCGAAAATG
CCATGTTGATGGATATCAATGGTGACGGCAAGCTGGATTGGGTGATCAGTCAACCGGGCTTAGCGGGCTACTTTAGCCGT
GATCCTGACCTTAGCCGTGATCCTGATCTTAGCTGGACCCAATTCATCCCGTTATCTACCTTGCCAGCGGAGTATTTCCA
TCCACAAGCGCAACTGGTCGATTTAGCCGGCAGCGGGTTATCTGATCTGGCGTTAGTCGGGCCAAAAAGTGTCCGCGTGT
ATACCAATCTGTGTGACAGTTTTGCTGCCGCAACCCAAGTAGCACAAGATGATGACATCACGCTACCACTACCCGGAGTT
CACTTCACTGAACTGGTGGCGTTCAGCGATGTGATGGGTTCGGGCCAACAACATCTGGTGCGAATACGCCACAATAGCGT
CACCTGCTGGCCCAATCTCGGCCATGGCCGCTTTGGTCACCCCCTCTCTTTACCGGGATTTAATCAGCCAGTTGAGCAAT
TTAATCCACTAGCGATCTATCTGGCAGATATTGATGGCTCCGGTACCATTGACCTTATTTATGCCACCACCAGCCAACTG
CTCATTTACCGCAACCAGAGTGGTAACCGCTTTGCCGAACCACTGGCTATCGCGTTGCCAACAGGCATTCGCTTTGATAA
TAGCTGCCAACTGTCACTGGCAGATATTCAGGGGCTGGGCGTGGCCAGCATTATGTTGAGTGTGCCGCACCCCACCACAC
AACATTGGCGCTATGATTTTGTCGCCAGTAAACCCTATTTACTGTGCACCACCAACAATAATATGGGCGCAGAGAGTCAG
TTGCTTTACCGCAGTTCTGTCCAATTCTGGTTGGATGAAAAAGCACAGGCGGCCAAACAGGGCCGATCACTGGCCTGCCA
ATTGCCCTTCCCGATCCATCTATTAGCGCAAACCACGCAATTTGATGAGATAACCGGTAACAGCCTGAGCCAAACCGCCC
GCTACTTCCATGGTTTTTATGATGGTGTGCAACGTGAATTCAGTGGTTTTGGCCGTGTCGATACGCTGGATACCGATACC
TCGGCACAAGGCAGTGCCGCTGAACGCACTGCGCCGACCAAAAGCAGTCGCTGGTTCCACACTGGCCGGGCAGGCAATGA
AACACTATGGCAAAGTGAGTATTGGCAGGGCGATGACCAAGCCTACTCATTGCTGCCTACCCGCCTGACAAAATTTATTA
ACAATACCCAAGGTGACGAATTACTCAGTGAACTCGATGATAATCAAACGTTTTGGTTGCACCGGGCGCTGAAAGGTTCA
TTGCTACGCAGCGAACTCTATGGTCTGGACGACAGCGAACTGGCGACACAACCGTATAGCGTTAACAGCTCTCGCTATCA
GGTGCGGCAAATTCAATCCTCTGCTGATGGAATCTCATCCCCGGTAGCCTTACCGATGGTGCTGGAACAACTCAGTTATC
ACTACGAACGTATCGCGCAAGACCCGCAATGCAGCCAGCAGATTGTGCTGCGTTGCAATGAATATGGTCACCCACTACAC
AGTGTGACAATCAATTATCCACGCCGCGATAAAGCCCGTATTTCCCCGTACTCCTGGCTGGCAAAGGAACATTGGGATAG
CCATTTTGACGAGCAACAGCAACAGTTGCGCATCACTGAAAGCCAGCAATCTTATCACCATGAGATCAGTGATAAATTCT
ATGTGCTGGGCCTGCCTGCCGGGCAGCGCAGTGATGTACTGACCTATCCCGACAATTTCGTGCCTACCGCGGGGATTCAT
TGGGAAGAATTACAGCAGCCAGAGGGCCTGCTTGGTACTAAAGCAGAGCGAACCTTTACCGCGCAGCAGCAGGTTTTCTA
CACCTCGGACACCATTCCGGGCCTGGTTGCCTACAGTCAACAGGCAGAATTTGACGATCAAACCTTGGTCGCATTGGATG
AATTATTACCAGCGAATGAGCGTAAACAGCAGCTTATCAAGGCCGGTTATCAAATAGCACCCCGTCTATTTGCTCGCACC
GGAGAAACGGATATTTGGGTCGCCCAAAGTGGGTTTACTGACTATGGTGATGCCTCCCGCTTCTATCGCCCCATCAGTCA
ACGTAGTACGCAATTAGTCGGGAAAACCATTTTGGAATGGGATGCCACCTGCTGTGCTGTCAGTGACATTATATTGGCCG
ATTACAGCATCACCCATGCTGAATACGATTATCGCTTTATCACCCCTTATCTGCTGATAGATATCAATGATAATCAACAT
TATATCGAGCTAGATGCGCTGGGGCGGGTTACCTCCAGCCGTTTTGCGGGCACCGAGATTGATCCACAAACCAATAAAGT
CATTGAAACCGGTTTTCCTTCCATCGCGGAACAGCCCTTTAGCGCCCCCAATTCAGTTGATAAAGCTCTCAGCCTGGAGA
ATACCCGCATTCCCGTCGCGCAGTTCTCTGTCTATCAACCTCAGAGTTGGATGATTTCATTACAGCTTGATGACATTGAA
ATATGGATTAGAGCCAATAACATTACTCCAGAATATCTATTCCAAAATCATATTCTGATCGATAACTATTATCTTTGCCC
CCTTGCGCTACGCCGCTGGGGAAGACAAAACAACCTTCTCATCACTGAAGGTGTTGGCCTGACATTGAAAAATCCCATGC
GCCAACCGCCTCATATATTAACCGTCGTCGTGGATAACTACTTTTCTGCTTCTGAACCACAACAGCATCAACAAACTCTC
GCTTTCAGTGACGGCTTTGGCCGCGTATTACTCAGCGCACGACGGGTGGAGACAGGACCCTCTTACTCATTCGATCCGGA
AAACGGCCTCTTAGTTGATGACAAAGGCAATCTGGTGCAACTCGAAGTCGATCAACGCTGGGCGGTCTCTGGCCGTACCG
AGTACGACAATAAAGGTCTGCCACGCCGCCGTTATCAACCTTATTTTTTCGACAACTGGATCTGGCTTTATATCGCCAAT
AACAGAACCCTCAAAGAGGCTTACGCCGATACCCATATTTACGACCCACTCGGGCGAGAAATAAAAGTGATCACCGCGAA
AGGTTATCTGCGACGAACTCACTATTTCCCGTGGTTTGTTATCAGTGAGGATGAAAATGACACGGCGTCAGAAATCACGC
CGAATCCCTAA

Protein sequence :
MENSKQQVAVAPLSLPKGGGAITGMGDSLGPIGPSGMATLTLPLPISAGRGYAPSLTLSYSSGSGNGPFGLGWQLGTMAI
RRRTNAQVPRYDEYDEFLAPNGEVMVVAADPQGSIERTEQSLNGEQFSVIRYLPRIEGNFHRIEYWRPRTNNSQAPFWLV
HSSDGQKHCLGYSAAARIADPLHPEHIAEWLLEESVSLSGEHIGYQYQAEDEQGIDEPSIYKAEKQNHPAASAQRYLKRV
VYGNRQAAYELYCLTQQPAPTSWLFSLIFDHGEYSNIAEQVPVIIKGKSWNFRQDAFSHFNYGFEVRTRRLCQQVLMYHN
LSALKGDEPDAQATLVSRLRLHYQHDAYATQLVGCQQLAHEPDGTKRSLPPLEFDYQDFSTRDALGWQPLTDWAEFNYQY
QMVDLNGEGMPGMLYQDSGHWIYRPPVRQPGTADGITFGAAQRLPSLPAMRENAMLMDINGDGKLDWVISQPGLAGYFSR
DPDLSRDPDLSWTQFIPLSTLPAEYFHPQAQLVDLAGSGLSDLALVGPKSVRVYTNLCDSFAAATQVAQDDDITLPLPGV
HFTELVAFSDVMGSGQQHLVRIRHNSVTCWPNLGHGRFGHPLSLPGFNQPVEQFNPLAIYLADIDGSGTIDLIYATTSQL
LIYRNQSGNRFAEPLAIALPTGIRFDNSCQLSLADIQGLGVASIMLSVPHPTTQHWRYDFVASKPYLLCTTNNNMGAESQ
LLYRSSVQFWLDEKAQAAKQGRSLACQLPFPIHLLAQTTQFDEITGNSLSQTARYFHGFYDGVQREFSGFGRVDTLDTDT
SAQGSAAERTAPTKSSRWFHTGRAGNETLWQSEYWQGDDQAYSLLPTRLTKFINNTQGDELLSELDDNQTFWLHRALKGS
LLRSELYGLDDSELATQPYSVNSSRYQVRQIQSSADGISSPVALPMVLEQLSYHYERIAQDPQCSQQIVLRCNEYGHPLH
SVTINYPRRDKARISPYSWLAKEHWDSHFDEQQQQLRITESQQSYHHEISDKFYVLGLPAGQRSDVLTYPDNFVPTAGIH
WEELQQPEGLLGTKAERTFTAQQQVFYTSDTIPGLVAYSQQAEFDDQTLVALDELLPANERKQQLIKAGYQIAPRLFART
GETDIWVAQSGFTDYGDASRFYRPISQRSTQLVGKTILEWDATCCAVSDIILADYSITHAEYDYRFITPYLLIDINDNQH
YIELDALGRVTSSRFAGTEIDPQTNKVIETGFPSIAEQPFSAPNSVDKALSLENTRIPVAQFSVYQPQSWMISLQLDDIE
IWIRANNITPEYLFQNHILIDNYYLCPLALRRWGRQNNLLITEGVGLTLKNPMRQPPHILTVVVDNYFSASEPQQHQQTL
AFSDGFGRVLLSARRVETGPSYSFDPENGLLVDDKGNLVQLEVDQRWAVSGRTEYDNKGLPRRRYQPYFFDNWIWLYIAN
NRTLKEAYADTHIYDPLGREIKVITAKGYLRRTHYFPWFVISEDENDTASEITPNP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tcaC'(2) CAI77376.1 putative insecticidal toxin complex protein Not tested tc-PAIYe Protein 0.0 58
tcdB1 AAL18487.1 TcdB1 Virulence tcd island Protein 0.0 49
tcdB2 AAO17202.1 TcdB2 Virulence tcd island Protein 0.0 49