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Name : mexB (YP_3760) Accession : NP_995031.1 Strain : Yersinia pestis 91001 Genome accession: NC_005810 Putative virulence/resistance : Resistance Product : multi-drug efflux protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0841 EC number : - Position : 4282748 - 4285834 bp Length : 3087 bp Strand : - Note : highly similar to Yersinia pestis CO92 YPO0421 and Yersinia pestis KIM mexB. Contains Polycystic kidney disease type 1 protein (Interpro|IPR000434). Contains Acriflavin resistance protein (Interpro|IPR001036) DNA sequence : ATGAAGCTGACTGATAATTTTATCAATAATAATACCCGTATCTGGCTAACGATTCTGTTGCTAGGTATTGGTGGCATTAT TGCCTATCTCAATATAGGCAGGCTGGAAGACCCGGCTTTTACCATCAAAACCGCGGTCGTTGTCACCCGCTATGATGGCG CATCGGCACAACAGGTTGAAGAAGAAGTCACGCTACCGTTGGAGAATGCCATTCAGGAACTCTCCTATGTGGATGACGTA ACCTCCATTTCCAGTGCCGGTTTATCGCAGATAACCATTAATATTCGTGCGCAATACGGCGCGAATGAGTTACCGCAAAT CTGGGATGAGCTGTGGCGTAAAATTAGCGATAACAGTGTTCGCCTACCACCAGGGGCCAGTGCCCCCATGGTCAACGATG ATTTTGGCGATGTTTACGGTTTCTTCTTCTCACTGACCGGTGACGGCTACAGTAATCAGGATCTGCGTAATTTTGCCGAG CAATTGCGGCGTGAATTAGTGTTGGTGCCCGGTGTGGGTAAAGTCGGCATCGTGGGTATTTTACCGGAAGAAGTTCAGGT AGAAATTTCCCGTGCGCAGATGACGGCCGCGGGTATTACACCGCAGCAGCTATCCGACTTGCTGAGTCGCCAAAACGTCG TGTCCGATGCAGGCCAGTTGCAGGTGGGCAGTGAGTCGATTCGCTTGCACCCGACTGGCGAATTCCAAAGCGTACAAGAG CTGGGGAATTTACTGGTCAGCCAACCCGGTAGCCCAAAAAGTGTCTATCTGCGCGATATTGCCACGGTAACCCAAGGCTT TGGTCATTCACCGACCAATATTTATCGCGCGAACGGTCAACCGGCATTGGCGTTAGGGATCTCGTTTGCTCCCAATGTTA ACGTGGTAAATGTTGGGAATGCGATTAAATCCCGTCTGGCGCAGCTTGAAGGTGAGCGCCCGTCCGGGATGCATATCAAT GTGTTCTACGATCAGTCTAAGGAAGTTGAAGGTGCGGTTAACGGCTTCATTCTTAACTTCCTGTTGGCACTGTTGATTGT TGTCGTTACCCTGCTGATCTTTATGGGGGTACGCAGCGGCGTGGTTATTGCCATCTCGCTGGCACTTAACGTGCTCGGAA CGTTGCTCATCATGTGGCTGTTTAACATCGAGCTACAGCGGGTATCGTTAGGGGCGCTGATCATTGCGCTGAGTATGCTG GTGGATAACGCCATCGTGGTGGTGGAAGGGGTGGTCGTTGGGCGTCAGCGCGGCGATAGCATTTCTACTGCTATCGGTAA TGTGGTGAAACGCTCGAAGATGCCGTTGCTGGGTGCGACCATTATTGCCATTTTGGCCTTTGCGCCTATCGGCCTGTCCA ATGATGCTACCGGCGAATATTGTAAGTCGCTATTCCAGGTGTTGCTCATCTCGTTAATGTTGAGCTGGATCACTGCGTTA ACGTTAACACCGGTGTTTGCCAAGTGGGCATTCCAGAACCAAAAACAGCCTGAAGCTGATGCGGATAAGCCGGTTAAACA ACCGTATGACGGCTGGTTATTCCGCTATTATCGGGTGGTGTTGAATAAATTACTGCAACACCGCAGTATTACATTGGTGC TCTTGGCCGCGTTATTAGTGGCGTCGGTTATCGGTTTTGGTCATGTTCGACAGAGCTTCTTCCCGCCTTCTAACACACCA ATCTTCTTTGTGGATATTTGGCTGCCTTATGGTACGGATATCAGCTATACCGAAGATATTGCAGCCAAAATTGAACAGCA TATCAAGCAGCAAAAAAATGTAGCGGATACCATGACAACCATAGGTCAGGGCGCAATGCGCTTTATGCTGACCTACAATG GTCAACGTCATTATCCTAACTATGCGCAGGTGATGGTCCGTACTGAGCAACTGGAGCAAATACCGGGCTTGATTGATGAA ATCGAGTCATATATGCATGACGAATATCCGCAGGTTGATGCGCAGATCAAACGCATCATGTTCGGGCCGTCAAACAACAG TTCTATTGAAGCTCGCTTTATTGGCCCCGATCCAGATGTGCTACGCACCTTGGCAGCCCAGGCGGAACAGGCGATTATCG CTGACCCAATGGCCGATGGTGCAAGGCATGACTGGCAGGATCGTAGCAAGATGATCCGGCCACAATTCTCCGATTATCTG GGCCGCGAGTTGGGGGTCGATAAACGCGAGGTGGATGGTACGTTGCGCATGAGTTTTGGTGGCTTGCCGGTTGGGTTATA CCGCGATGGTACCCGCCTGATACCTATTGTCCTACGCACACCGGACTCTGAGCGGCTCAATGCTGAGCGGTTGAACGATG TGATGGTCTGGAGCCAGGCGCGCCAAGCCTTTATCCCGATCGACAACGTGGTCACCAGTTTTGAAACCGAGTGGGAAGAT CCACTGATTATGCGTCTGGATCGTAAGCGGACACTGACGGTACAAACGGATCCAACCCATCAGGGCGGTGAGACCTCTTC CGAGTTGTTGCAACGGATCAAGCCGGGCGTTGAAGCCATTACCTTGCCACGGGGCTATGAACTGGAGTGGGGCGGCGATT ACGAAAGTACCAAAGAAGCACAGCGGGGTATTTTCATTAGCTTGCCGATCGCGTTTCTGCTTATGTTTGTTGTGACCGTG CTGATGTTTAGCTCGGTGCGTAATGCACTGGCTATTTGGCTGACGGTACCACTGGCATTAATTGGTGTGACCTTCGGCTT CCTACTGACGGGGATTCCGTTCGGCTTTATGGCCTTGCTGGGGTTATTAAGCCTGAGTGGGATGTTGATCCGTAATGGTA TTGTACTGGTCGAAGAGATTGGTCTACAGCGGCAAGAGAAACCGTTGCGTGAGGCGATTATCGATGCTTCCACCGCGCGT TTACGGCCGATCATGCTGACCGCATTTACCACTGTGTTGGGGCTGGCTCCGCTGCTGAGCGATGCCTTCTTCCAGAGTAT GGCGGTGGTGATTATGTTTGGCTTGGGCTTCGCGACAGTACTGACATTGCTGGTACTGCCAGTGATTTACAGCAGTATGA ATCCAGAGCCTAAAGAAAAGATCCACGATGAGCCAGTGAGTGAATAA Protein sequence : MKLTDNFINNNTRIWLTILLLGIGGIIAYLNIGRLEDPAFTIKTAVVVTRYDGASAQQVEEEVTLPLENAIQELSYVDDV TSISSAGLSQITINIRAQYGANELPQIWDELWRKISDNSVRLPPGASAPMVNDDFGDVYGFFFSLTGDGYSNQDLRNFAE QLRRELVLVPGVGKVGIVGILPEEVQVEISRAQMTAAGITPQQLSDLLSRQNVVSDAGQLQVGSESIRLHPTGEFQSVQE LGNLLVSQPGSPKSVYLRDIATVTQGFGHSPTNIYRANGQPALALGISFAPNVNVVNVGNAIKSRLAQLEGERPSGMHIN VFYDQSKEVEGAVNGFILNFLLALLIVVVTLLIFMGVRSGVVIAISLALNVLGTLLIMWLFNIELQRVSLGALIIALSML VDNAIVVVEGVVVGRQRGDSISTAIGNVVKRSKMPLLGATIIAILAFAPIGLSNDATGEYCKSLFQVLLISLMLSWITAL TLTPVFAKWAFQNQKQPEADADKPVKQPYDGWLFRYYRVVLNKLLQHRSITLVLLAALLVASVIGFGHVRQSFFPPSNTP IFFVDIWLPYGTDISYTEDIAAKIEQHIKQQKNVADTMTTIGQGAMRFMLTYNGQRHYPNYAQVMVRTEQLEQIPGLIDE IESYMHDEYPQVDAQIKRIMFGPSNNSSIEARFIGPDPDVLRTLAAQAEQAIIADPMADGARHDWQDRSKMIRPQFSDYL GRELGVDKREVDGTLRMSFGGLPVGLYRDGTRLIPIVLRTPDSERLNAERLNDVMVWSQARQAFIPIDNVVTSFETEWED PLIMRLDRKRTLTVQTDPTHQGGETSSELLQRIKPGVEAITLPRGYELEWGGDYESTKEAQRGIFISLPIAFLLMFVVTV LMFSSVRNALAIWLTVPLALIGVTFGFLLTGIPFGFMALLGLLSLSGMLIRNGIVLVEEIGLQRQEKPLREAIIDASTAR LRPIMLTAFTTVLGLAPLLSDAFFQSMAVVIMFGLGFATVLTLLVLPVIYSSMNPEPKEKIHDEPVSE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0395_A1355 | YP_001217299.1 | AcrB/AcrD/AcrF family transporter | Not tested | VPI-2 | Protein | 3e-166 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| mexB | NP_995031.1 | multi-drug efflux protein | BAC0519 | Protein | 0.0 | 51 |
| mexB | NP_995031.1 | multi-drug efflux protein | BAC0428 | Protein | 0.0 | 51 |
| mexB | NP_995031.1 | multi-drug efflux protein | BAC0526 | Protein | 0.0 | 48 |
| mexB | NP_995031.1 | multi-drug efflux protein | BAC0425 | Protein | 1e-166 | 41 |
