Gene Information

Name : clpB2 (YP_3673)
Accession : NP_994944.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : Clp ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4183297 - 4185900 bp
Length : 2604 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 clpB and Yersinia pestis KIM y3669. Contains Chaperonin clpA/B (Interpro|IPR001270). Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains AAA ATPase (Interpro|IPR003593, (GO:000

DNA sequence :
ATGGGAGCGATAACGGTGTATCAACGCGAACGTCTTTTTAATCGATTGGGCACTTTTGCCTATAAAACTTTTGTTGAAGC
CACCCGTCTTTGCCGCAGTTATCGGCATGAGTATGTGGAGCTTGAACATTGGTTAAAAATTCTCATGGATCAACAGCGTG
GGGATATTCCTGCTCTACTGACGCATTACGGACTGAGCCAGACGGTTATCTCCACGCAATTGGATCGCATTATTCAGCAT
ATGCCCGTCACCAAAGCATCGGTGCAGGATTTATCATCACGCTTGGAGTCCGTGGTCGAAGGCGGATTGGTGTTGAGCCA
ATTGATGGCGTCACCTTCTCCTATCCGTACCTCGCATATTTTACTGGCACTATTACAGGATACCCAGCATCAGCGCTGGT
TATACCGCCTGTGCGATGAATTCAAAAAGCTGCCGGTCCCACAGGTTGCAGAGGAATATGAAGGCCTATTAGTTAACTCC
ATTGAACAGACCAGCGAGGTTCAAAGAGGCGACGCATTAGTGACGGAAACGGACAGCAGCTCATCAAAAGAAGCGCATGC
GGCATTGAACAAATGGTGTAACGACCTTACCCAGCAAGCCCGTGACGGTGAGATTGACCCCGTTATTGGTCGTGAAGCAG
AACTGCGTCAAGTGATTGATATTTTACTCCGTCGCCGTCAGAACAACCCTATTTTGGTTGGGGAAGCGGGGGTCGGTAAA
ACGGCGGTGGTTGAAGCGCTAGCGCGAAAACTGGCCAGTGGCGATGTCCCTCCGCTGTTGCAAGGGGCGCGTCTGCTTTC
TCTGGATTTGGGGAGGATGCAAGCCGGTGCCAGTATGCGCGGTGAATTTGAATCACGTCTTAAATCCCTGATCGATGGCA
TCAGCCAATCGGATACCCCGGTTATTCTGTTTTGTGATGAAGCCCATACGTTGGTGGGGGCAGGCGGGCAGGCGGGCACG
GGGGATGCGGTCAACCTGCTTAAACCGATGTTGGCGAGGGGCGCATTGCGCATGATCGCCGCCACCACCTGGTCAGAGTA
TAAACAGTTTATTGAACCTGACGCCGCGCTGACCCGGCGTTTCCAGCGGGTATTGATTGGCGAGCCAAACGAATCTACCG
CCGTCGATATGCTACGGGCGATTGCGCCACATTTTGCTCAACATCATAACGTCACTATCCGCGACGGTGCCATTCACGCG
GCGGTGCGCCTGTCATTACGCAACCTGCCTTCCCGGCAGTTGCCCGATAAAGCCATCAGTCTGCTCGACACCGCTTGCGC
GCGGGTCGCGCTCAGCCAATATGCCCAACCACAGGCGATTGAACAGTTATCGGCCCAACTGGATGTGCTCAAAACCGAGC
ATCAATATCTGGTACGGGAGAAGCAACTGGGCGAAGCGGTTGATCAACGGCTAGATGACGTTCAGACACAGATCCAGGCG
TTTGAACATGAACTAACCGCCTTGCAAAGCCGCCATCTGCATGAGCAACAGCTAGTGAGGGAGGTCCTGCCGGAGGGAGA
AGGCAGTGGCATGATGACGGAAAATGCCCGCTGGGGTGAACTGATGGCGTTACAGGAAGCGTCGCCACTGGTCTATCCAT
GGGTTGATGAGCAGAGCATCGCCGCGGTGCTTTCCGATTGGACCGGGATCCCGTCCGGCAAAATGTTGCAGGACGATATT
GAATGCGTCCTGAATCTTGAACAGCGTCTCGGTGATCATATTTTCGGGCAACGCAACGCTATCAAAGAGATTTCGCAGGC
GATACGTATTGCTCGGGCGGGCATCCAGTCTCAGGAGCGGCCACTCGGGATCTTCCTGCTGGCGGGGTCAACCGGTACGG
GCAAAACAGAAACGGCCAATGTACTGGTCGAAACCTTGTATGGCGGTGCTCATAACCTTATTACCTTCAATATGAGTGAG
TTCCAAGAGGCGCATACCTTATCCACGCTGAAAGGCGCACCTCCGGGCTATGTCGGCTATGGCAAGGGGGGGAAATTAAC
CGAAGCGGTAAGACGCAAACCTTATTCGGTCATCCTGCTTGATGAGTTTGATAAAGCTCACGCCGATATTCAGGACGCCT
TTTATCAGGTCTTCGACAAAGGGTGGATGGAAGATGCCGAAGGGCGTCGGGTCAGTTTCCGCCAGTGTTTCATCTTACTG
ACCTGTAATCAGGGCGCGGAAGAGATCGAACAGGCTTACCTCACCGCCAACGATATCAAACCCGGTGCATTAAAACCGTT
GGTATACGACGCCCTGTTGCGCCGCTTTGCGCCAGCGCTGTTAGCCAGGGTCAATATCATTCCTTATATCCCATTAGATC
AGGACGCTCTGGCACAGATCGCCTCTCATCATCTTGCGCGCTTACAAACGCGCCTGTGGGATGAAATTGGTGCCACTTTG
GTGACCGAGGGGGATATCCCCGGCTGGATCGCCTCACGGGTTTGCAGCCATCCGAACCATGGTCGTGCGGTGGAAGAACT
CTTGCGTCAAACCTTACTTCCCGCTGTTGGCAATGAAGTGTTGAAGCGTCGCCATGAGGCTGAACCGCTGAGAGAGATAC
GCCTGATTGTTGAGGAGACAGAACTGAGTATTGAGTTCGCGTAG

Protein sequence :
MGAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALLTHYGLSQTVISTQLDRIIQH
MPVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHILLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNS
IEQTSEVQRGDALVTETDSSSSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGK
TAVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTPVILFCDEAHTLVGAGGQAGT
GDAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRRFQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHA
AVRLSLRNLPSRQLPDKAISLLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQA
FEHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSIAAVLSDWTGIPSGKMLQDDI
ECVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQERPLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSE
FQEAHTLSTLKGAPPGYVGYGKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILL
TCNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQIASHHLARLQTRLWDEIGATL
VTEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEVLKRRHEAEPLREIRLIVEETELSIEFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-148 45
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-107 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB2 NP_994944.1 Clp ATPase VFG2076 Protein 4e-156 44
clpB2 NP_994944.1 Clp ATPase VFG2084 Protein 2e-123 41