Gene Information

Name : YP_3616 (YP_3616)
Accession : NP_994888.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : transposase for insertion sequence IS100
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG4584
EC number : -
Position : 4112799 - 4113821 bp
Length : 1023 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 YPO4010 and Yersinia pestis KIM y4031. Contains Integrase, catalytic domain (Interpro|IPR001584, (GO:0006310)). Contains IS21-like element transposase, HTH domain (Interpro|IPR007101)

DNA sequence :
ATGGTCACTTTTGAGACAGTTATGGAAATTAAAATCCTGCACAAGCAGGGAATGAGTAGCCGGGCGATTGCCAGAGAACT
GGGGATCTCCCGCAATACCGTTAAACGTTATTTGCAGGCAAAATCTGAGCCGCCAAAATATACGCCGCGACCTGCTGTTG
CTTCACTCCTGGATGAATACCGGGATTATATTCGTCAACGCATCGCCGATGCTCATCCTTACAAAATCCCGGCAACGGTA
ATCGCTCGCGAGATCAGAGACCAGGGATATCGTGGCGGAATGACCATTCTCAGGGCATTCATTCGTTCTCTCTCGGTTCC
TCAGGAGCAGGAGCCTGCCGTTCGGTTCGAAACTGAACCCGGACGACAGATGCAGGTTGACTGGGGCACTATGCGTAATG
GTCGCTCACCGCTTCACGTGTTCGTTGCTGTTCTCGGATACAGCCGAATGCTGTACATCGAATGGGCTGACAATATGCGT
TATGACACGCTGGAGACCTGCCATCGTAATGCGTTCCGCTTCTTTGGTGGTGTGCCGCGCGAAGTGTTGTATGACAATAT
GAAAACTGTGGTTCTGCAACGTGACGCATATCAGACCGGTCAGCACCGGTTCCATCCTTCGCTGTGGCAGTTCGGCAAGG
AGATGGGCTTCTCTCCCCGACTGTGTCGCCCCTTCAGGGCACAGACTAAAGGTAAGGTGGAACGGATGGTGCAGTACACC
CGTAACAGTTTTTACATCCCACTAATGACTCGCCTGCGCCCGATGGGGATCACTGTCGATGTTGAAACAGCCAACCGCCA
CGGTCTGCGCTGGCTGCACGATGTCGCTAACCAACGAAAGCATGAAACAATCCAGGCCCGTCCCTGCGATCGCTGGCTCG
AAGAGCAGCAGTCCATGCTGGCACTGCCTCCGGAGAAAAAAGAGTATGACGTGCATCTTGATGAAAATCTGGTGAACTTC
GACAAACACCCCCTGCATCATCCACTCTCCATCTACGACTCATTCTGCAGAGGAGTGGCGTGA

Protein sequence :
MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPPKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATV
IAREIRDQGYRGGMTILRAFIRSLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEWADNMR
YDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLCRPFRAQTKGKVERMVQYT
RNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNF
DKHPLHHPLSIYDSFCRGVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
y1094 CAC43410.1 IS100 transposase; transposase ORFA Not tested PAI III 536 Protein 2e-162 99
y2411 NP_669718.1 transposase Not tested HPI Protein 2e-163 99
unnamed CAB46599.1 IS100 transposase Not tested HPI Protein 1e-163 99
YPTB1585 YP_070113.1 transposase Not tested HPI Protein 2e-163 99
api83 CAF28557.1 transposase Not tested YAPI Protein 1e-163 99
unnamed CAA21403.1 - Not tested HPI Protein 2e-163 99
y1093 CAD33720.1 ORF A protein Not tested PAI I 536 Protein 8e-162 99
s0035 CAD33773.1 ORF A protein Not tested PAI I 536 Protein 2e-162 99
y1094 CAD42088.1 OrfA protein of IS100 transposase Not tested PAI II 536 Protein 2e-162 99
orfA CAE85182.1 OrfA protein, transposase, IS100 Not tested PAI V 536 Protein 2e-162 99
y1093 YP_002346890.1 transposase for insertion sequence IS100 Not tested HPI Protein 2e-163 99
unnamed AAG37051.1 unknown Not tested espC PAI Protein 1e-152 96

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YP_3616 NP_994888.1 transposase for insertion sequence IS100 VFG1626 Protein 1e-162 99
YP_3616 NP_994888.1 transposase for insertion sequence IS100 VFG1607 Protein 1e-162 99
YP_3616 NP_994888.1 transposase for insertion sequence IS100 VFG1461 Protein 4e-162 99
YP_3616 NP_994888.1 transposase for insertion sequence IS100 VFG1514 Protein 1e-162 99
YP_3616 NP_994888.1 transposase for insertion sequence IS100 VFG0780 Protein 7e-153 96