Gene Information

Name : clpB3 (YP_3467)
Accession : NP_994748.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : Clp ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3939616 - 3942264 bp
Length : 2649 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 clpB3 and Yersinia pestis KIM clpB. Contains Chaperonin clpA/B (Interpro|IPR001270). Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains AAA ATPase (Interpro|IPR003593, (GO:000

DNA sequence :
ATGACAACGCATTCAGCACACTTATTACGCCGCTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCTGCCACCCTGTG
TCAGACCCGCGCCCATGCCGAGATCACTGTCGAACACTGGTTGTTAAAACTGCTGGAGCAGGGCGAAGGCGATATCACGG
TGATTGCCCGGCGTTATGAGTGGGACATGGACAGCTTGTGGCAAGGGTTACTGGCCTATCTGGATACTTTGCCGCGCACG
GTACAGGGTAAACCCCAACTGTCCGCCGCGTTGCAGCAACTGATCAAAAGTGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATAAATTCGCCATCATTATTGGCCGCCGATGCCGCCTGGC
CGTTGCTCAGCCTGAGCACTACCCAACTACACCGCTTGTTGCCGTTGCTGGACAGCCAATCCGACGAACGCCCTGAAATA
CAGCAGGCCGCAGCACTGGCAGACAGCCCGGTCAATCTGACCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTTACCCTCGATGTCACCGCCAAAGCCCGTGCCAACCAGATTG
ATCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGACATCCTGTCGCGCCGCCGTAAAAACAACCCGATTTTG
GTGGGTGAACCGGGTGTGGGGAAAACCGCCTTGGTTGAAGGGCTGGCACTGCGCATTGCCGAGGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGTGCCGGGGTCAAAGGCGAGTTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTGCAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCCAACCTGCTGAAACCGGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAG
TGGACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCAT
ATTCTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTCCTGACCGGCCGCCAACTGCCGGACAAAGCGGT
GGATCTGCTCGATACCGCCGGTGCCCGGGTGCGCATGAGCATTGACACCTTGCCGACTGCGCTGATGGCGATTAACGCCG
AGCTGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACCTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTA
CCTGAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAAAAACGGCT
GACCACCCTGATTATCGAGGCGCGTCAGGATATCGCCAACGTGGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGA
GCCAAGGCAACGCGCCGCTGCTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGCGTG
CCGCTGAGCAGTCTGTTGAAAGACGAACAGACCGATTTGTTGCAACTGGAAAACCATCTCGCCACCCGCGTAGTCGGGCA
GGATACGGCGCTGGGTGCGCTGGCGCAACGGCTGCGGGCGGCGAAAACCGGGCTGACATCAGAGAATGGCCCGCTGGGGG
TGTTCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGCTGGCACTGGCCGACAGCCTGTTCGGCGGCGAG
AAATCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCTCACACCGTCTCCCAGTTGAAAGGGTCGCCCCCAGGTTA
TGTTGGCTACGGTCAGGGTGGTGTATTAACCGAAGCGGTACGTAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTGG
AAAAAGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGGGGGTTCATGCGCGACGGTGAAGGGCGCGAA
ATTGATTTTCGTAACACAGTGATCCTAATGACGGCCAATTTAGGCAGTGATCATCTGATGCAGTTACTGGATGAACAACC
GGAAGCGACGCACAGTGATTTACACGAGCTGCTGCGCCCGATCCTGCGCGATCATTTCCAGCCCGCGCTATTAGCCCGCT
TCCAGACCTTGATCTACCGCCCACTGAATGCCATCGCATTGCGCACCATCGTCGAGATGAAACTGGCACAGGTCGCTAAA
CGCCTGAACAAACATTACGGCCTGCACTGCACCATTGAGGAAAGCCTCTACGACACACTGGTCGCCGCCTGCCTGCTGCC
GGACACCGGCGCACGCAACATCGACAGCCTGCTCAATCAACAAATCTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCA
TGAGCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGGATGAAGCCGACGGCATTACCCTTGAATTTGAAGGAGGC
GAAAAATGA

Protein sequence :
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLAYLDTLPRT
VQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEI
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQSQGNAPLLSLDVDVRTVAAVIADWTGV
PLSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYRPLNAIALRTIVEMKLAQVAK
RLNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGG
EK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-136 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB3 NP_994748.1 Clp ATPase VFG2084 Protein 2e-135 43
clpB3 NP_994748.1 Clp ATPase VFG2076 Protein 2e-150 43