Gene Information

Name : iucD (YP_3447)
Accession : NP_994730.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : siderophore biosynthesis protein IucD
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : -
Position : 3915929 - 3917257 bp
Length : 1329 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 iucD and Yersinia pestis KIM iucD. Contains Flavin-containing monooxygenase FMO (Interpro|IPR000960, (GO:0006118)). Contains Sugar transporter superfamily (Interpro|IPR005829, (GO:0016020))

DNA sequence :
ATGAATCAGCCTCTGGATTTCATCGGCATTGGCATCGGCCCATTTAACCTCAGTATTGCCGCACTTGGCAGTGAAGTTTC
TGGCTTTAACAGTAAATTTCTCGAACGTAAACCGCACTTTTCCTGGCACCCTGGCATGATGGTGCCGGACTGCCATATGC
AGACCTGCTTCCTGAAAGACTTGGTCAGCGCAGTCTCCCCGACTAACACGTACAGCTTTCTTAACTATCTGGTGCAGCAT
AAGAAATTCTACCGTTTTCTGACCACCGAGCACCGGACCGTTTCCCGTGAGGAGTTTGCGGACTACCTCCGTTGGGCCGC
CAGTGGCATGAGTTCGCTCGAGTTTAGCCAAGATATTCAGAGCGTGGACTTTGACGACCAGCAGCGCCATTTTGTCGTTA
CCACCCCGCGTAATGTCTACCACGCGCGCCACGTTTGCCTGGGGATAGGCAAACGCATCAAATTGCCAGACTGCGTGACC
GAGCAAAATGACCGCTGCTTCCATGCCAGCGAAATGGCACTGCGTAATCCAGATCTGACCGGTAAACGCGTCACCATTGT
GGGCGGCGGCCAGAGCGGGGCGGACCTGTTCCTGAACATCTTTCTCGCTGCATGGGGGCAGCCAAAGCAGCTGAACTGGA
TTTCACGCCGTAACAACTACAACGCGCTGGATGAAGCCGCTTTTGCCAATGAGTACTTCATGCCGGAATACGTTGAGAGT
TTCTACACCCTGAACGACAGCGCCAAACAGCATATGCTGGCAGAACAGAGAATGACCTCTGACGGCATTACCAGTGAATC
ACTACTGGCGATTTACCGTGCTATGTACCACCAATTTGAAGTGTTACATGAAAAACCGTGGGCGCGCCTGCTCCCCAGCC
GCTCACTGACCAATATGCATACGCGCGGCAACGGTTACCAATTACTCACCCATCACCATCTCGATCAAGGCACAGAAACT
TTTGATACCGATGTGGTAATCTTCGCCACGGGTTATCAGCAGGATCGACCGGCGTTTCTCGATCCATTAGCTGATCGTCT
GCAAACCACCGCCGATTGCCAGTACCAAGTGGCTCCAGATTTTGTCCTCGACTGGCAAGGCCCGCGTGAAAACTGCTTGT
TCGCCGTGAATGCCGGTATGCATAGCCACGGCATTGCCGAACCTCAGCTCAGCCTGATGGCTTGGCGATCAGCACATATT
CTCAACCGGGCTTTAGGGCGCACTCAGTTCGATTTAACTTCCACCCCGGCGGTGATCCAATGGCGCAGCCAACAGTCGGG
TGTCCCTGCCCACCCGGAACATCCCGTGCTCAACTGCATCGACATTTAA

Protein sequence :
MNQPLDFIGIGIGPFNLSIAALGSEVSGFNSKFLERKPHFSWHPGMMVPDCHMQTCFLKDLVSAVSPTNTYSFLNYLVQH
KKFYRFLTTEHRTVSREEFADYLRWAASGMSSLEFSQDIQSVDFDDQQRHFVVTTPRNVYHARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMALRNPDLTGKRVTIVGGGQSGADLFLNIFLAAWGQPKQLNWISRRNNYNALDEAAFANEYFMPEYVES
FYTLNDSAKQHMLAEQRMTSDGITSESLLAIYRAMYHQFEVLHEKPWARLLPSRSLTNMHTRGNGYQLLTHHHLDQGTET
FDTDVVIFATGYQQDRPAFLDPLADRLQTTADCQYQVAPDFVLDWQGPRENCLFAVNAGMHSHGIAEPQLSLMAWRSAHI
LNRALGRTQFDLTSTPAVIQWRSQQSGVPAHPEHPVLNCIDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 2e-136 60
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 7e-137 60
iucD AAD44749.1 IucD Virulence SHI-2 Protein 1e-136 60
iucD AAK71634.1 IucD Virulence SHI-3 Protein 5e-137 60
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 2e-136 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucD NP_994730.1 siderophore biosynthesis protein IucD VFG0618 Protein 8e-137 60
iucD NP_994730.1 siderophore biosynthesis protein IucD VFG1084 Protein 3e-137 60
iucD NP_994730.1 siderophore biosynthesis protein IucD VFG0937 Protein 3e-137 60