Gene Information

Name : iutA (YP_3446)
Accession : NP_994729.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : ferric siderophore receptor
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1629
EC number : -
Position : 3913677 - 3915857 bp
Length : 2181 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 iutA and Yersinia pestis KIM iutA. Contains TonB-dependent receptor protein (Interpro|IPR000531, (GO:0016020))

DNA sequence :
ATGAAACACAAACACCTCTGGGTATTAAATCCGTGTCTGCTGGTCATGCTCACACCAGCGGCGTGGGCAGAGGATCAACT
TGTGGTTTCAGCCAACCGCTCACACCGCAGCGTGGCAGAAATGGCGCAAACAACTTGGGTGATTGAAGGCCAGGAACTTG
AACAACAAGTTCAAGGCGGCCTGGAAATCAAAGACATCTTGGCTCAATTGATCCCAGGTATCGACGTCAGCAGCCAAGGC
CGTACCAACTACGGCATGAACATGCGTGGCCGCTCAATCATGGTGATGATCGACGGCGTGCGGCTGAACTCTTCACGTAG
CGACAGCCGCCAACTCGATTCGATCGATCCGTTTAATATTGCACACATTGAAGTCATCTCCGGTGCGACGTCACTTTATG
GCGGGGGTAGCACGGGGGGCTTGATCAATATCGTGACCAAAAAAGGCCAGGAAGGAAAACAGGTTGAGTTGCAAATTGGC
GGCAAAACCGGCTTTAACAGCCATAACGACCACGATGAGAACATCTCGGCCGCCATGAGTGGGGGGACTGAGCGCGCATT
CGGCCGATTCTCTGTTTCTTATCAACGTTATGGGGGGTGGTACGACGGCAAAGGCAATGAGGTTTTGATCGACAACACCC
AGACCGGCTTGCAATATTCTAACCGTCTGGACGTGATGGGCACGGGAACCCTCAATATCGACGAAAACCAGCAATTGCAG
CTAACCACTCAGTATTTCAACAGCGAATCCGATGGCAAACACGGCTTGTATCTGGGGCAAAACTTCTCAGCAGTAACGGG
TACCGGGCAGGCCTCCAACAGCGCAGCGCTAAATTCAGACCGTATTCCGGGTACCGAACGCCATCTCATCAACTTGCAAT
ACTCCAACACGGATTTCTGGGGGCAGGATTTAGTGGCGCAAGTGTATTACCGTGATGAATCACTAACCTTCTACCCATTC
CCAACACTGAAAGATGGCAAGGTGAGCACTATCGGTGCATCACAGCAAAAAACCGATTTCTACGGCAGTAAACTGACATT
GAACAGTGAACCTATCGATAGCCTAACACTGACTTACGGTATCGATTTGGAACATGAAAGTTTCAATGCCAATCAACAGT
TCTTTAATCTGGCGAAGGCACAGCAATCCGGCGGCATGACGTTAGAAAATGCCTACAACGTTGGCCGTTACCCAAGTTAT
ACCACCACCAACCTGGCTCCCTTCTTACAAACCCGCTATGACATCAACCCGATTTTCACTCTGAGCGGCGGTGTGCGTTA
CCAGTACACAGAGAACAAGGTTGATGATTTTGTGGGTTACGCACAACAACAAGCGATTGCCAGCGGCTCCGCGACTTCCG
CTGATCCCGTACCTGGTGGGAAAACGGATTACAACAACTTCCTGTTCAATGCCGGTTTACTGGCGCACCTGACAGAAAGC
CAGCAGACCTGGTTCAACTTTTCACAAGGATTTGAGATCCCGGATCTGGCGAAATATTACGGTTCTGGCTCCTACACGCT
GGTTAACGGTCACTATCAGTTGCAAAACAGTGTCAACGTGAATGACTCCAAACTGGAGGGCATCAAGGTTGATTCCTATG
AGCTGGGCTGGCGCTATACCGGCGATAACCTGCGCACCCAAATGGCGGGTTATTACTCGCTTTCTGATCAGACTATCTCG
ATCAACAAAACAGACATGACCATCAATGTGTTACCGGATAAGCGCCGAATCTATGGGGTAGAAGGCGCAGTAGATTACTT
CTTCGATAACAGCGAATGGAGTGCCGGTGCAACATTTAACCTAATTAAGTCGGAAACTAAGGTTAGCGGTAAGTGGCAGA
AACTGACTATCGATGCTGCCAGCCCGTCGAAAGCCACCGCCTACATTGGCTGGGCACCGGGTGATTGGAATCTGCGCGTG
CAATCCCAACAAACGTTCGATGTTTCCGATAGCAAGGGTGACAAAATAGACGGTTACAACACCATCGATTTTCTCAGTAG
TTACGCCCTACCCGTGGGAAAACTCAGTTTCAGTATCGAAAACTTGCTGGACAAAGAGTACACCACCGTTTGGGGTCAGC
GCGCACCGATTCTGTATAGCCCAACCTACGGCTCACCCAACTTATACAGCTATAAGGGCCGTGGCCGGACTTTTGGTGTG
AACTACTCAGTGTTGTTCTGA

Protein sequence :
MKHKHLWVLNPCLLVMLTPAAWAEDQLVVSANRSHRSVAEMAQTTWVIEGQELEQQVQGGLEIKDILAQLIPGIDVSSQG
RTNYGMNMRGRSIMVMIDGVRLNSSRSDSRQLDSIDPFNIAHIEVISGATSLYGGGSTGGLINIVTKKGQEGKQVELQIG
GKTGFNSHNDHDENISAAMSGGTERAFGRFSVSYQRYGGWYDGKGNEVLIDNTQTGLQYSNRLDVMGTGTLNIDENQQLQ
LTTQYFNSESDGKHGLYLGQNFSAVTGTGQASNSAALNSDRIPGTERHLINLQYSNTDFWGQDLVAQVYYRDESLTFYPF
PTLKDGKVSTIGASQQKTDFYGSKLTLNSEPIDSLTLTYGIDLEHESFNANQQFFNLAKAQQSGGMTLENAYNVGRYPSY
TTTNLAPFLQTRYDINPIFTLSGGVRYQYTENKVDDFVGYAQQQAIASGSATSADPVPGGKTDYNNFLFNAGLLAHLTES
QQTWFNFSQGFEIPDLAKYYGSGSYTLVNGHYQLQNSVNVNDSKLEGIKVDSYELGWRYTGDNLRTQMAGYYSLSDQTIS
INKTDMTINVLPDKRRIYGVEGAVDYFFDNSEWSAGATFNLIKSETKVSGKWQKLTIDAASPSKATAYIGWAPGDWNLRV
QSQQTFDVSDSKGDKIDGYNTIDFLSSYALPVGKLSFSIENLLDKEYTTVWGQRAPILYSPTYGSPNLYSYKGRGRTFGV
NYSVLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iutA NP_839219.1 ferric siderophore receptor Virulence SHI-2 Protein 0.0 66
iutA NP_709458.2 ferric siderophore receptor Virulence SHI-2 Protein 0.0 66
iutA AAD44750.1 IutA Virulence SHI-2 Protein 0.0 66
iutA AAK71635.1 IutA Virulence SHI-3 Protein 0.0 66
iutA YP_002414042.1 Ferric aerobactin receptor Virulence Not named Protein 0.0 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iutA NP_994729.1 ferric siderophore receptor VFG0619 Protein 0.0 66
iutA NP_994729.1 ferric siderophore receptor VFG1085 Protein 0.0 66
iutA NP_994729.1 ferric siderophore receptor VFG0936 Protein 0.0 66