Gene Information

Name : fliI (YP_3029)
Accession : NP_994327.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 3369665 - 3371005 bp
Length : 1341 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGAGTGAATCTCCGGCTCTCGATCATGCCCTGAAATCTATCGAAAACATTCATCTGGCCCGAGTGGCGGGCCGGTTAGT
GCGAGTGACGGGGCTGCTGCTGGAAAGTGTCGGCTGCCGTTTGGCTATCGGCCAGCGCTGTCGGATTGAGAGTGTCGATG
AGACCTTTATTGAGGCGCAGGTGGTTGGGTTTGATCGAGACATCACCTATCTGATGCCCTTCAAGCATCCCGGTGGGGTG
CTAGGCGGGGCGCGGGTGTTCCCGAGTGAGCAGGACGGTGAGTTGTTGATCGGCGATAGCTGGCTCGGGCGAGTTATTAA
TGGGTTAGGAGAACCCCTTGATGGCAAAGGCCAACTGGGCGGGAGTACGCCACTGCAACAGCAACTACCGCAAATCCATC
CATTACAACGGCGGGCGGTAGACACCCCGTTGGATGTCGGCGTCAACGCCATTAACGGCCTGCTGACTATCGGCAAAGGC
CAGCGGGTGGGGCTGATGGCGGGCAGTGGGGTCGGTAAAAGTGTGTTGCTCGGCATGATAACCCGCTATACCCAGGCGGA
TGTGGTGGTGGTGGGGCTGATTGGCGAGCGTGGCCGCGAGGTAAAAGAGTTTATCGAGCATTCACTCCAGGCCGCCGGTA
TGGCGAAATCCGTGGTGGTGGCGGCACCTGCCGACGAGTCACCGCTGATGCGCATCAAGGCCACCGAACTCTGCCATGCC
ATTGCGACCTACTACCGTGACAAAGGCCACGATGTGCTGCTACTGGTGGATTCACTGACCCGTTATGCCATGGCCCAGCG
GGAAATTGCCCTCTCACTGGGGGAGCCGCCCGCCACCAAAGGCTACCCGCCGTCCGCTTTTAGCATTATCCCCAGATTGG
CTGAAAGCGCCGGTAACAGCAGCGGTAACGGCACCATGACCGCGATTTATACCGTATTGGCCGAAGGTGACGATCAACAA
GATCCCATTGTCGATTGCGCCAGAGCGGTCTTGGACGGCCACATTGTGTTATCGCGTAAACTGGCCGAAGCGGGGCACTA
TCCGGCGATTGATATCAGCCAGTCGATCAGCCGTTGCATGAGCCAGGTTATCGGTAGCCAGCAGGCCAAAGCCGCCAGTC
TACTGAAACAGTGCTATGCCGATTATATGGCGATCAAACCTTTGATCCCATTGGGCGGTTATGTGGCAGGGGCAGATCCG
ATGGCTGATCAGGCGGTGCATTACTACCCGGCGATTACCCAATTTCTGCGCCAGGAGGTAGGCCACCCGGCACTATTTTC
TGCCAGCGTTGAACAACTGACCGGGATGTTCCCCTCCTTTGCCCCCACTGACGAGGCGTAA

Protein sequence :
MSESPALDHALKSIENIHLARVAGRLVRVTGLLLESVGCRLAIGQRCRIESVDETFIEAQVVGFDRDITYLMPFKHPGGV
LGGARVFPSEQDGELLIGDSWLGRVINGLGEPLDGKGQLGGSTPLQQQLPQIHPLQRRAVDTPLDVGVNAINGLLTIGKG
QRVGLMAGSGVGKSVLLGMITRYTQADVVVVGLIGERGREVKEFIEHSLQAAGMAKSVVVAAPADESPLMRIKATELCHA
IATYYRDKGHDVLLLVDSLTRYAMAQREIALSLGEPPATKGYPPSAFSIIPRLAESAGNSSGNGTMTAIYTVLAEGDDQQ
DPIVDCARAVLDGHIVLSRKLAEAGHYPAIDISQSISRCMSQVIGSQQAKAASLLKQCYADYMAIKPLIPLGGYVAGADP
MADQAVHYYPAITQFLRQEVGHPALFSASVEQLTGMFPSFAPTDEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-73 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-80 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-80 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 6e-81 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-81 44
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-82 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-81 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-82 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-82 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-82 44
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 8e-68 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-70 44
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-77 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-69 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 7e-70 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-70 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-73 44
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-64 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-70 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-62 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 5e-68 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 5e-68 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 6e-70 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-68 42
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-68 42
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-65 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-65 42
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-66 41
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-65 41
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-65 41
escN NP_290268.1 hypothetical protein Virulence LEE Protein 8e-66 41
ECs4568 NP_312595.1 EscN Virulence LEE Protein 8e-66 41
escN AAC31513.1 L0034 Virulence LEE Protein 6e-66 41
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-66 41
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-65 41
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-65 41
escN AAC38383.1 EscN Virulence LEE Protein 7e-66 41
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-65 41
escN AAK26715.1 EscN Virulence LEE Protein 3e-65 41
escN AAL57542.1 EscN Virulence LEE Protein 3e-65 41
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI NP_994327.1 flagellum-specific ATP synthase VFG1254 Protein 1e-106 55
fliI NP_994327.1 flagellum-specific ATP synthase VFG2499 Protein 2e-100 54
fliI NP_994327.1 flagellum-specific ATP synthase VFG2331 Protein 2e-97 53
fliI NP_994327.1 flagellum-specific ATP synthase VFG0192 Protein 7e-79 44
fliI NP_994327.1 flagellum-specific ATP synthase VFG0048 Protein 6e-80 43
fliI NP_994327.1 flagellum-specific ATP synthase VFG0390 Protein 1e-75 42
fliI NP_994327.1 flagellum-specific ATP synthase VFG0515 Protein 2e-68 42
fliI NP_994327.1 flagellum-specific ATP synthase VFG0812 Protein 3e-66 41
fliI NP_994327.1 flagellum-specific ATP synthase VFG0730 Protein 4e-66 41
fliI NP_994327.1 flagellum-specific ATP synthase VFG1778 Protein 2e-53 41