Gene Information

Name : fimC6 (YP_3012)
Accession : NP_994311.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : fimbrial chaperone protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 3352157 - 3352876 bp
Length : 720 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 YPO0699 and Yersinia pestis KIM y3479. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains Bacterial pili assembly chaperone (Interpro|IPR001829, (GO:0030288))

DNA sequence :
ATGAAGAAGCTCTCATTAATCGCGTTGACCAGCACAGTGGTATTCACCAGTTATACCGCCAATGCTGCGATTGCATTAGA
CCGGACGCGAATTATTTATAACGGGCAGGATAAGTCCATTAGCCTGAATATCAGTAATGAAAATAAAACACTGCCCTATT
TAGCACAGGCGTGGATTGAGAATGAACAACAGCAAAAAGTCACCACCCCGTTAGTGGCAACGCCACCAGTTCAGCGAGTA
GAAGCGGGTAAGAAAAGCGCGGTGCGTATCTCTGCCACCCCTGAGGCGCTGAAATTGCCACAAGATCGCGAGTCACTGTT
CTACTTCAATCTGCGTGAAATTCCGCCTCGCAGTGAAAAATCTAATGTCATGCAGATTGCCTTACAAACCAAAATCAAAC
TGTTCTACCGGCCAGAAGGGATTACCCCTGCTACGGGCCAAATCTGGCAGGAACAACTGGTTCTGCATAAAACGGCGCAA
GGTTTTCGGCTAGAGAACCCCACTCCCTATTACATTACGGTCGTTGGGCTGGCGGAGAAAGGTAAGTCATCGGCTGACAG
CAATTTTCAACCTTTGATGGTTGCGCCCAAATCCAGTGCTGAGCTGAAATCTGCCAGTTTCACCGCCCCCGTCCTGACCT
ACATTAACGATTATGGTGGCCGACCAGAACTGAGTTTCAGTTGCAGCGGCAGTACTTGCCGGGCAGCTAAAGCGATTTAA

Protein sequence :
MKKLSLIALTSTVVFTSYTANAAIALDRTRIIYNGQDKSISLNISNENKTLPYLAQAWIENEQQQKVTTPLVATPPVQRV
EAGKKSAVRISATPEALKLPQDRESLFYFNLREIPPRSEKSNVMQIALQTKIKLFYRPEGITPATGQIWQEQLVLHKTAQ
GFRLENPTPYYITVVGLAEKGKSSADSNFQPLMVAPKSSAELKSASFTAPVLTYINDYGGRPELSFSCSGSTCRAAKAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
papD NP_755464.1 PapD protein Virulence PAI I CFT073 Protein 3e-66 62
pixD CAE85158.1 PixD protein Not tested PAI V 536 Protein 9e-74 61
papD YP_854253.1 pilus assembly protein chaperone PapD Virulence PAI I APEC-O1 Protein 2e-74 59
papD AAZ04423.1 P pilus chaperone Virulence PAI I APEC-O1 Protein 1e-74 59
prfD CAD42028.1 PrfD protein Virulence PAI II 536 Protein 2e-74 59
papD AAL67413.1 PapD Virulence PAI II CFT073 Protein 2e-74 58
papD_2 NP_757033.1 PapD protein Virulence PAI II CFT073 Protein 2e-74 58
papD YP_002414014.1 Chaperone protein PapD Not tested Not named Protein 2e-74 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fimC6 NP_994311.1 fimbrial chaperone protein VFG0885 Protein 1e-66 62
fimC6 NP_994311.1 fimbrial chaperone protein VFG1547 Protein 9e-75 59
fimC6 NP_994311.1 fimbrial chaperone protein VFG0896 Protein 1e-74 58