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Name : thyA (YP_2875) Accession : NP_994180.1 Strain : Yersinia pestis 91001 Genome accession: NC_005810 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 3190447 - 3191241 bp Length : 795 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGAAACAGTATCTGGATTTGATGAAAAAAGTGCTGGAAGAAGGCACACCTAAAGCTGACCGTACCGGTACCGGCACTCT GTCAATTTTTGGGCATCAGATGCGTTTCAATTTACAAGACGGTTTCCCATTGGTCACCACCAAGCGTTGCCACCTACGTT CGATTATCCATGAGTTGTTATGGTTCCTGAATGGCGATACCAACATTGCTTATCTGAAGGAAAATAATGTCTCAATCTGG GATGAATGGGCAGATGAAAACGGCGATCTTGGTCCGATTTATGGTAAACAATGGCGTGCTTGGGGGGCTGCTGATGGCCG AAAAATTGACCAGTTGAGTAACGTAGTCAATCAACTGAAGCAGGACCCTGATTCGCGCCGGATTATTGTTTCTGCGTGGA ATGTGGGCGAACTGGATCAAATGGCGTTGGCACCATGCCATGCCTTTTTCCAGTTCTACGTGGCTGATGGCAAACTTTCT TGCCAACTGTACCAACGCTCTTGCGATGTGTTCCTTGGCTTGCCATTTAACATTGCCAGCTATGCGTTATTAGTTCACAT GATGGCGCAGCAGTGTGATCTGGCCGTAGGCGATTTTGTCTGGACTGGCGGGGATACTCACTTGTATAGCAACCATATTG ACCAGGCGCATCTGCAATTGAGCCGTGAGCCACGAGTATTACCGAAACTGGTGATCAAACGTAAACCTGATTCATTGTTT GACTACCATTTCGATGATTTTGATATTGAGGGCTACGATCCTCACCCTGGTATTAAAGCCCCTATCGCGATTTAA Protein sequence : MKQYLDLMKKVLEEGTPKADRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLNGDTNIAYLKENNVSIW DEWADENGDLGPIYGKQWRAWGAADGRKIDQLSNVVNQLKQDPDSRRIIVSAWNVGELDQMALAPCHAFFQFYVADGKLS CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVGDFVWTGGDTHLYSNHIDQAHLQLSREPRVLPKLVIKRKPDSLF DYHFDDFDIEGYDPHPGIKAPIAI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 2e-85 | 63 |
| thyA | YP_189147.1 | thymidylate synthase | Not tested | ¥ÕSP¥â | Protein | 2e-56 | 45 |
