Gene Information

Name : dapA1 (YP_2647)
Accession : NP_993962.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : N-acetylneuraminate lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0329
EC number : -
Position : 2935688 - 2936587 bp
Length : 900 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 YPO3024 and Yersinia pestis KIM y1458. Contains Dihydrodipicolinate synthetase (Interpro|IPR002220)

DNA sequence : 
ATGCGTATGAAAAAGTTAACCGGCCTGATCGCAGCTCCGCACACTCCCTTTGATGAACAGGGCGAGGTCAATTATCCGGT
CATTGACCAAATTGCCGAGCATCTGATCAATGATGGTGTGAAAGGCGTTTATGTCTGTGGTACCACTGGCGAAGGCATTC
ATTGCTCAGTTGATGAGCGCAAGAAAATTGCTGAACGCTGGGTAAATGCCGCTCAAGGCAAACTGAGCATTACCTTACAC
ACCGGTGCTCTCAGTATTAAAGATGCGGTTGATCTCTCTCGTCATGCGGAAACACTGGATATCTTCGCAACCTCAGCCAT
CGGCCCCTGTTTCTTTAAACCGGGTAATCTGGATGACCTAATCGCTTATTGTCAGGCAATAGCCGCGGCAGCACCGTCGA
AGGGCTTCTATTACTACCACTCCGGTATGTCCGGTGTAAATTTGGACATGGAACAGTTTCTGATCAAAGCGGAATCCAAG
ATCCCTAACTTGTCAGGAATTAAATTCAATAACGCTGATTTGTATGAGTTTCAACGCTGTTTACGTGTGAGTGGCGGTAA
ATTTGATATTCCGTTTGGCGTTGATGAACATCTGCCAGGTGGATTAGCTGTAGGGGCTATTGGCGCTGTTGGCAGCACTT
ATAACTATGCCGCTCCGCTGTTCCATAAAATTATCGCTGACTTTAATGCGGGTGATCAGGTTGCGGTACAGCGTGGAATG
GATCACGTTATCGCCCTGATCCGTGTGCTGGTCGAATTCGGTGGTGTTGCCGCCGGTAAGGCCGCGATGCAATTACATGG
TATTGATGCCGGTAACCCACGTCTGCCACTGCGTGCCTTGACCAAAGAACAGAAGCAAACCGTGGTTAACAGAATGCGTG
ACGCTATTACGTTGCAGTAA

Protein sequence : 
MRMKKLTGLIAAPHTPFDEQGEVNYPVIDQIAEHLINDGVKGVYVCGTTGEGIHCSVDERKKIAERWVNAAQGKLSITLH
TGALSIKDAVDLSRHAETLDIFATSAIGPCFFKPGNLDDLIAYCQAIAAAAPSKGFYYYHSGMSGVNLDMEQFLIKAESK
IPNLSGIKFNNADLYEFQRCLRVSGGKFDIPFGVDEHLPGGLAVGAIGAVGSTYNYAAPLFHKIIADFNAGDQVAVQRGM
DHVIALIRVLVEFGGVAAGKAAMQLHGIDAGNPRLPLRALTKEQKQTVVNRMRDAITLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1776 NP_231411.1 N-acetylneuraminate lyase Not tested VPI-2 Protein 3e-102 76
VC0395_A1374 YP_001217317.1 dihydrodipicolinate synthetase family protein Not tested VPI-2 Protein 3e-102 76
VPI2_0024c ACA01841.1 dihydrodipicolinate synthase/N-acetylneuraminate lyase Not tested VPI-2 Protein 8e-102 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dapA1 NP_993962.1 N-acetylneuraminate lyase VFG1109 Protein 1e-102 76