Gene Information

Name : nrdF (YP_2450)
Accession : NP_993774.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 2723501 - 2724472 bp
Length : 972 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAACGTAGTAAAACCAATAACACGTATCAGCGCCATCAACTGGAATAAAATTGAAGACGATAAAGATCTGGAAGTGTG
GAACCGCCTGACATCTAATTTTTGGCTGCCGGAAAAAGTCCCGCTGTCGAATGATATTCCGTCGTGGGCGACACTCACGC
CACATGAACAACAACTGACTATCCGGGTTTTTACCGGCCTCACGCTATTGGATACGATCCAGAATACACTGGGCGCACCT
GCATTAATTAAAGATGCGATTACCCCCCATGAGGAAGCGATATTTTCAAATATCAGCTTTATGGAGGCCGTACACGCACG
TTCTTATAGCTCTATTTTTTCTACACTTTGTCTGACATCAGATGTAGACGATGCCTACCGTTGGAGTGAGGATAATGGGC
CACTCCAAAAGAAAGCTGATATTATTTCACAGCATTACCATAATGACGATCCGCTGAAGAAAAAAATAGCCAGTGTATTT
TTGGAATCATTTTTATTCTATTCCGGATTTTATTTACCCATGTATTGGTCCAGTAGAGCTAAATTAACCAACACCGCAGA
TCTTATTCGGCTTATTATTCGGGACGAAGCTGTCCATGGATATTATATCGGCTATAAGTTTCAAAAGGGGTTGGGAAAAA
TAGATAGTGCCCATCGTCAGGAAATAAAGAATTTCGCTTTCGACCTACTGCAAGATCTCTATGATAATGAAGTGCGTTAT
ACCGAAGATCTGTATGACCACGTTGGCTGGACAGAGGATGTAAAAAAATTTCTCCACTACAATGCCAATAAAGCACTCAT
GAATTTAGGCTATGAGGCATTATTTCCCGCCAGCCAGGCGGCGGTCAGCCCTGCAATTCTGGCCGCGTTGTCGCCAAACG
CAGATGAAAACCACGATTTTTTCTCCGGATCAGGTTCATCTTATGTGATCGGTAAAGCGGTCAATACTGAAGACGAAGAT
TGGGATTTTTAA

Protein sequence :
MNVVKPITRISAINWNKIEDDKDLEVWNRLTSNFWLPEKVPLSNDIPSWATLTPHEQQLTIRVFTGLTLLDTIQNTLGAP
ALIKDAITPHEEAIFSNISFMEAVHARSYSSIFSTLCLTSDVDDAYRWSEDNGPLQKKADIISQHYHNDDPLKKKIASVF
LESFLFYSGFYLPMYWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKFQKGLGKIDSAHRQEIKNFAFDLLQDLYDNEVRY
TEDLYDHVGWTEDVKKFLHYNANKALMNLGYEALFPASQAAVSPAILAALSPNADENHDFFSGSGSSYVIGKAVNTEDED
WDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-107 67