Gene Information

Name : yfeD (YP_2230)
Accession : NP_993559.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : chelated iron transport system membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 2478007 - 2478900 bp
Length : 894 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 yfeD and Yersinia pestis KIM yfeD. Contains ABC transporter, family 3 (Interpro|IPR001626, (GO:0016020)). Contains Sodium:dicarboxylate symporter (Interpro|IPR001991, (GO:0016020)). Contains Preprotein translocase Se

DNA sequence : 
ATGAATATGCTGTTCAGTTTGATCAGTGAGCCATTCGCCTACCCCTTTATGCAGCGGGCAATTGTCGCGGCAATCGTCAC
TGGTGTGGTCTGCGCGATACTCTCTTGCTACCTGGTACTCAAAGGGTGGTCGCTAATGGGAGATGCTATTTCTCATGCTG
TGCTGCCAGGGATTGTTCTGGCTTTTTGGCTCGGTATCCCTCTGGTCATCGGCGCTTTTGTCTCAGGGATATTTTGTGCC
GTGGCAACTGGCTATTTAAAAGAAAACAGCCGGGTTAAAGAAGATACCGTCATGGGGATTGTTTTTTCTGGCATGTTCGC
GTTCGGCTTAGTGCTGTTCTCCCGTATAGATACTGACCAGCACCTCAGCCACATTTTGTTCGGTAACATGCTGGGGATTT
CGCTGACAGAACTGAAACAGACCCTGTGGATCGCAGGTTTCACGCTATTGGTGGTGTTACTAAAGCGCAAAGACTTTATG
TTGTACTGTTTCGATCCAAACCATGCGCGGGTTATCGGGCTACCCGTTAAGTTTCTGCATTACGGTTTACTTTGCTTACT
GGCATTGACTATCGTCGCGTCATTGCAGGCAGTTGGCGTTATTCTCGTCATCGCCATGTTGATAGCGCCGGGTATTATCG
CCTTTATGATTTGTCGTAGTTTTGATCAAATGCTGGTTGTCGCGACACTGGTTTCAGTGGTCGCCTGTGTTTTAGGTACA
TTAATCAGTTTTCATATTGATGGTGCAACAGGCCCATGCATCGTGATTATTCAAGCTTTATTCTTTGTTGTCGCCCTCAT
TTACAACCATATAAAACCGATTAAAGACCGAAAAATGGCACCACTCACCAAGGCAGTAAATCCAGAAAATACAGCCCCAA
GTAACCTGCCATAG

Protein sequence : 
MNMLFSLISEPFAYPFMQRAIVAAIVTGVVCAILSCYLVLKGWSLMGDAISHAVLPGIVLAFWLGIPLVIGAFVSGIFCA
VATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRIDTDQHLSHILFGNMLGISLTELKQTLWIAGFTLLVVLLKRKDFM
LYCFDPNHARVIGLPVKFLHYGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMICRSFDQMLVVATLVSVVACVLGT
LISFHIDGATGPCIVIIQALFFVVALIYNHIKPIKDRKMAPLTKAVNPENTAPSNLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 6e-64 54
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 6e-64 54
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 6e-64 53
sitD NP_461785.1 permease Virulence SPI-1 Protein 3e-64 52
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 2e-64 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeD NP_993559.1 chelated iron transport system membrane protein BAC0442 Protein 4e-130 100
yfeD NP_993559.1 chelated iron transport system membrane protein BAC0352 Protein 1e-64 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeD NP_993559.1 chelated iron transport system membrane protein VFG0528 Protein 1e-64 52