Gene Information

Name : yfeC (YP_2229)
Accession : NP_993558.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : chelated iron transport system membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 2477126 - 2478010 bp
Length : 885 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 yfeC and Yersinia pestis KIM yfeC. Contains ABC transporter, family 3 (Interpro|IPR001626, (GO:0016020))

DNA sequence : 
ATGCTGGAACTTTTACTGCAACCGTTTAATTATAATTATATGGTCAAGGCCATTTGGGTTAGTGCGATTGTGGGGGCCGT
TTGTGCTTTTCTATCCGCTTATCTGATGCTAAAAGGCTGGTCGCTGATGGGTGATGCGTTATCACACTCAGTCGTGCCTG
GGGTTGCAGGGGCTTATGCTCTTGGTTTTCCCTATGCCGCTGGCGCTTTCTTTACGGGTATGCTTGCCGCCTTGGCAATG
ACGCTAGTACGCCACATTACCCGCCTACGTGAAGATGCCATTATCGGTTTTATCTTTTCTACCTTTTTTGCTGTTGGGCT
TTTAATCGTTTCACTCAATCCCACATCAGTGAATGTTCAGTCGATCATCTTCGGCAATATTCTGGGTATTGCTGATGAAG
ATGTCTTGCAGGTAGAAATCATTATTTTGGTTTCTTTTGTGATTTTATGTTTGATCTGGAAAGATTTATTAGCGGTGTTT
TTCGATGAAAGCCACGCCATGTCAATTGGTTTATCCCCACTGCGCTTAAAAATCTTATTCTTTACGCTCCTGAGCGCCTG
TACTGTCGCCGCTTTACAAACCGTGGGGGCCATTTTAGTGATAGCTATGGTCGTCACTCCAGGGGCAACAGCCTATTTAC
TGACCGATCGTTTCGGCCGCTTGCTCATTATTGCCATTGCTATTGGGGCCATTACCAGTGCTTTCGGCGCGTATCTCAGT
TTTTATCTGGATGGGGCAACCGGTGGCGTTATTGTCACCTTACAAACACTGGTATTCCTGCCGGCTTTCTTCTTTGCCCC
CAAACACGGATTACTGGCAACCCGATACCGCACACGGTTGAAACGTCGTCATCCGCCGGTTCATCTTCCGGAGGATAACC
TATGA

Protein sequence : 
MLELLLQPFNYNYMVKAIWVSAIVGAVCAFLSAYLMLKGWSLMGDALSHSVVPGVAGAYALGFPYAAGAFFTGMLAALAM
TLVRHITRLREDAIIGFIFSTFFAVGLLIVSLNPTSVNVQSIIFGNILGIADEDVLQVEIIILVSFVILCLIWKDLLAVF
FDESHAMSIGLSPLRLKILFFTLLSACTVAALQTVGAILVIAMVVTPGATAYLLTDRFGRLLIIAIAIGAITSAFGAYLS
FYLDGATGGVIVTLQTLVFLPAFFFAPKHGLLATRYRTRLKRRHPPVHLPEDNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 3e-80 66
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-80 66
sitC NP_461784.1 permease Virulence SPI-1 Protein 5e-80 66
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 4e-80 66
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 4e-80 66
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-44 43
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 5e-45 43
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 1e-44 43
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 1e-44 43
sitD NP_461785.1 permease Virulence SPI-1 Protein 7e-45 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeC NP_993558.1 chelated iron transport system membrane protein BAC0441 Protein 9e-126 100
yfeC NP_993558.1 chelated iron transport system membrane protein BAC0351 Protein 2e-80 66
yfeC NP_993558.1 chelated iron transport system membrane protein BAC0352 Protein 3e-45 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeC NP_993558.1 chelated iron transport system membrane protein VFG0527 Protein 2e-80 66
yfeC NP_993558.1 chelated iron transport system membrane protein VFG0528 Protein 3e-45 43