Gene Information

Name : yfeA (YP_2227)
Accession : NP_993556.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : periplasmic-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 2475268 - 2476239 bp
Length : 972 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 yfeA and Yersinia pestis KIM yfeA. Contains Periplasmic solute binding protein (Interpro|IPR006127, (GO:0030288)). Contains Adhesion lipoprotein (Interpro|IPR006128, (GO:0007155)). Contains Adhesin B (Interpro|IPR006

DNA sequence : 
GTGATGTTAATTAAGAAAAAAAGTCCTTATCTCAAAATGATAGAACGACTAAACTCCCCTTTTCTACGGGCTGCAGCCTT
GTTTACAATTGTCGCATTCTCATCGCTGATCAGTACCGCTGCTTTAGCAGAAAATAATCCCAGCGATACAGCCAAAAAAT
TCAAAGTTGTGACTACATTCACAATCATTCAGGATATTGCACAAAATATCGCCGGTGATGTTGCCGTGGTGGAGTCAATA
ACCAAGCCAGGCGCAGAGATTCATGACTATCAACCTACCCCACGAGATATTGTAAAAGCACAGTCAGCAGACCTTATCTT
ATGGAATGGCATGAATCTGGAGCGTTGGTTTGAGAAGTTCTTCGAAAGTATTAAAGATGTCCCGTCTGCCGTCGTGACCG
CAGGTATTACACCCCTGCCTATCCGTGAAGGCCCCTATAGCGGCATTGCCAACCCACATGCCTGGATGTCGCCATCAAAT
GCGCTAATATATATTGAGAATATCCGCAAAGCGTTAGTTGAACACGATCCCGCTCATGCAGAAACCTATAACCGTAACGC
GCAAGCCTATGCTGAAAAAATTAAGGCGCTAGATGCTCCACTGCGTGAGCGTTTATCTCGTATTCCTGCGGAACAGCGTT
GGTTAGTAACCAGTGAAGGGGCATTTAGTTATCTTGCCAAAGACTATGGTTTTAAAGAGGTTTACTTATGGCCAATCAAT
GCAGAGCAACAAGGTATTCCGCAACAAGTTAGACACGTGATTGATATTATTCGCGAAAATAAAATTCCGGTGGTGTTTAG
TGAGAGTACTATTTCCGACAAACCCGCCAAACAAGTGAGTAAAGAAACCGGTGCACAATATGGCGGCGTGCTATATGTTG
ATTCTCTGTCGGGCGAAAAAGGCCCGGTCCCCACTTACATCAGTTTAATTAACATGACTGTAGATACTATCGCTAAAGGA
TTCGGTCAATGA

Protein sequence : 
MMLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESI
TKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSN
ALIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPIN
AEQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKG
FGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-84 63
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 4e-84 63
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 4e-84 63
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 4e-84 63
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 3e-84 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeA NP_993556.1 periplasmic-binding protein BAC0439 Protein 2e-135 100
yfeA NP_993556.1 periplasmic-binding protein BAC0349 Protein 2e-84 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfeA NP_993556.1 periplasmic-binding protein VFG0525 Protein 2e-84 63