Gene Information

Name : int2 (YP_1660)
Accession : NP_993013.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1826607 - 1827869 bp
Length : 1263 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 int and Yersinia pestis KIM y2393. Contains Phage integrase (Interpro|IPR002104, (GO:0015074)). Contains Phage integrase (Interpro|IPR002104, (GO:0015074))

DNA sequence : 
ATGTCCCTTACCGACGCAAAAATCCGCACCCTCAAGCCTTCTGATAAACCCTTTAAAGTCTCCGATTCTCACGGTCTGTA
TCTGCTGGTCAAGCCGGGTGGCTCCCGCCACTGGTATCTCAAATACCGTATTAGCGGTAAAGAATCCCGCATTGCGCTGG
GTGCCTATCCAGCCATCTCCCTGTCTGATGCGCGACAGCAACGTGAAGGTATCCGTAAAATGCTGGCGCTGAATATCAAC
CCGGTACAGCAGCGGGCTGCTGAACGTGGCTCACGAACACCGGAGAAAGTTTTTAAAAACGTGGCGCTGGCGTGGCATAA
AAGTAACAGGAAATGGTCGCAGAACACCGCCGACCGTCTGCTTGCCAGCCTGAACAATCACATCTTTCCGGTCATCGGGA
ACCTACCTGTATCAGAACTTAAACCCCGTCATTTCATTGACCTGCTGAAAGGGATCGAGGAAAAAGGTCTGCTGGAGGTT
GCGTCCCGCACACGGCAGCACCTGAGTAACATAATGCGCCATGCGGTCCATCAGGAGTTAATCGATACGAACCCTGCAGC
AAACCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCGCTGGAGCGGCTGCCTGAACTGCTTG
AACGTATTGGGGCATATCATCAGGGCCGTGAACTGACCCGGCATGCCGTTCTGCTGATGCTGCATGTGTTCATTCGCTCC
AGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCGCGACGCGAGAACCCAT
TATTGGCGTGCGTTATTCCGGCCGCGGGGCAAAAATGCGAATGCCGCATATCGTCCCCCTCTCAGAACAGTCCATCGCCA
TTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACTGATCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAATAAGGCACTGCGGGTGATGGGTTACGACACGAAAAAGGATATCTGCGGTCACGGCTTCCGGGCAAT
GGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGGAGCACAATA
CCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTAGAAGCCCGCAAAGCGATGATGCAGTGGTGGTCGGATTATCTG
GAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Protein sequence : 
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAISLSDARQQREGIRKMLALNIN
PVQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int2 NP_993013.1 integrase Not tested HPI Protein 0.0 100
int CAA21384.1 - Not tested HPI Protein 0.0 100
int YP_002346908.1 integrase Not tested HPI Protein 0.0 100
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 0.0 100
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 9e-150 99
unnamed AAD17660.1 unknown Not tested HPI Protein 0.0 99
int CAB59974.1 integrase Not tested HPI Protein 0.0 99
int CAA08754.1 integrase Not tested HPI Protein 0.0 99
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 4e-135 99
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-116 59
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-116 59
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-106 56
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 7e-113 56
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 7e-113 56
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 3e-106 55
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-106 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-106 55
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-106 55
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 2e-106 55
int AAK00456.1 Int Not tested SHI-1 Protein 5e-98 55
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-101 55
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-107 55
int AAL51003.1 CP4-like integrase Not tested LEE Protein 1e-107 55
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 9e-108 55
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 7e-108 55
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 9e-108 55
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-106 55
int AAL51028.1 CP4-like integrase Not tested LEE Protein 7e-108 55
int-phe AAL60261.1 Int-phe Not tested LEE Protein 7e-108 55
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-108 55
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-108 55
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-108 55
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 5e-107 55
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 2e-107 55
int CAC81896.1 integrase Not tested LEE II Protein 2e-99 55
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 6e-92 49
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-95 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
int2 NP_993013.1 integrase VFG0626 Protein 6e-107 55
int2 NP_993013.1 integrase VFG1536 Protein 6e-102 55
int2 NP_993013.1 integrase VFG1693 Protein 1e-107 55