Gene Information

Name : hpcR (YP_1632)
Accession : NP_992987.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Resistance
Product : homoprotocatechuate degradative operon repressor
Function : -
COG functional category : K : Transcription
COG ID : COG1846
EC number : -
Position : 1782558 - 1783034 bp
Length : 477 bp
Strand : +
Note : highly similar to Yersinia pestis CO92 hpcR and Yersinia pestis KIM hpaR. Contains Bacterial regulatory protein, MarR family (Interpro|IPR000835, (GO:0006355))

DNA sequence :
TTGTTACTTATGCATGAATCACTGACCATCGCATTATTGCAGGCTCGTGAAGCCGCTATGGCTTTTTTTCGGCCTATCTT
GAAAGCCAATCATCTGACTGAGCAGCAATGGCGGATCATTCGAGTGCTCGCGGATAATCGCTCAATTGATTTTCATGGGC
TGGCCCGCCAAACCTGTATTTTACGTCCAAGCCTAACGGGGATTTTGACGCGAATGGAGCGTAACAATTTGATTTTTCGC
CTCAAACCCGTCAACGATCAGCGCAAACTTTATGTCTCCTTAACTCAGGAGGGACAAAATTTGTATGACAACGCTCGGCC
ACAGGTTGAAGAAGGTTACAGGCTAATTGAGGCAGCATTTTCACCAGATAAAATGGCGCAACTCTCTTTACTGCTGGATG
AATTCATTACCGTGGGTAATAAACATCGGCAAGCGAATGAGATGTCAGAAAATGAGATGTTAGAAGATGAAGAGTGA

Protein sequence :
MLLMHESLTIALLQAREAAMAFFRPILKANHLTEQQWRIIRVLADNRSIDFHGLARQTCILRPSLTGILTRMERNNLIFR
LKPVNDQRKLYVSLTQEGQNLYDNARPQVEEGYRLIEAAFSPDKMAQLSLLLDEFITVGNKHRQANEMSENEMLEDEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpcR AAO17176.1 HpcR Not tested tcd island Protein 3e-51 77

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hpcR NP_992987.1 homoprotocatechuate degradative operon repressor BAC0505 Protein 6e-34 55