Gene Information

Name : hpaE (YP_1630)
Accession : NP_992986.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1779404 - 1780801 bp
Length : 1398 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 hpaE and Yersinia pestis KIM hpaE. Contains Aldehyde dehydrogenase (Interpro|IPR002086, (GO:0008152), (GO:0016491))

DNA sequence :
ATGAAGATTGTTAACCATTGGATTGATGGGAAAAATATTACCAGCAATGACTATTTCACAACAATCAATCCGGCCACTGG
CGAGGTGCTGGCTGACGTGGCAAGCGGGGGGATAAAAGAGATCAACCAAGCCGTTGCTGCCGCGAAAAGTGCTTTCCCTC
ACTGGGCTAACCTGCCGATGAAAGTGCGTGCCCGTCTAATGCGCCGTCTGGGGGAGTTGATTGAGCAACAGATCCCAGAA
ATAGCGCAGATGGAAACGCAGGATACCGGCCTGCCCATTTATCAAACGCAAAATGCCTTGATCCCGCGGGCAGCACATAA
CTTCGAATTTTTTGCCGAAATTTGTCAGCAAATGAATGGCCAGACGTATCCGGTTGACGATCAAATGTTGAATTACACCT
TGGTGCAACCCGTGGGAGTGTGTGCGTTGGTCTCCCCTTGGAATGTCCCTTTTATGACGGCGACCTGGAAGGTCGCGCCT
TGTTTGGCGCTGGGTAACACCGCGATATTGAAAATGTCGGAGCTATCGCCACTGACCGCAGACAAACTGGGTGAACTGGC
CTTAGAGGCGGGTATACCGGCGGGGGTTCTCAACGTGGTACAAGGATATGGGGCCACTGTCGGTGATGCATTGGTATGTC
ATCAGGATGTCCGAGCTATCTCTTTTACCGGCGGCACCGCGACGGGAAACCGCATCATGCAACGTGCCGGGTTGAAAAAA
TACTCCATGGAACTCGGTGGTAAATCCCCGGTACTTATCTTCGACGATGCTGATATCGAACGGGCTATGGATGCGGCGCT
ATTTTCCATCTTCTCTCTCAATGGTGAACGTTGCACGGCGGGTTCGCGCATTTTTATTCAAGAGAGTCTCTATTCGGCAT
TTATTCAACGTTTTGCTGAGCGGGCCAGCCGTTTACGTGTGGGGGACCCACAAGATCTCGACACTCAAGTTGGCGCATTG
ATCAGTAAACCGCATTGGGACAAAGTTTCCGGCTATATCCAGTTGGGGATAGAGGAGGGGGCCACGTTGTTGGCAGGGGG
GCCGGATAAACCCATCGACCTACCTGCTCATCTGCGCGGAGGGCACTTCCTGCGTCCAACGGTGTTGGCCGATGTTGATA
ACCGAATGCGGGTTGCTCAGGAAGAGATTTTTGGACCGGTCGCTTGCCTGATCCCCTTTAAGAATGAAGACGCCGGACTG
CGTTTGGCCCGAAGTATTGAAGCCGGCATGGTGTTCGTGAATACCCAGAATGTGCGGGATCTCCGCCAGCCATTTGGCGG
CATCAAGGCATCGGGAACCGGGCGTGAAGGGGGAAAGTACAGTTTTGATGTTTTTGCTGAAGTGAAAAACGTCTGTATTT
CCATGGGGGAGCATCCGATCCCCCGTTGGGGGATGTAA

Protein sequence :
MKIVNHWIDGKNITSNDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPMKVRARLMRRLGELIEQQIPE
IAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNGQTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAILKMSELSPLTADKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAERASRLRVGDPQDLDTQVGAL
ISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRGGHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGL
RLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGEHPIPRWGM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 81