Gene Information

Name : ysuD (YP_1422)
Accession : NP_992786.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : iron-siderophore transport system, ATP-binding component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 1571622 - 1572470 bp
Length : 849 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 YPO1533 and Yersinia pestis KIM ysuD. Contains ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687, (GO:0005524)). Contains ABC transporter (Interpro|IPR003439, (GO:0016020)). Contains AAA ATPase (Interpro|IPR0

DNA sequence : 
GTGAGATCCCAAAGAGAGCTAACATCCCCCATGACACCATTGGAGAACCCGGGCGATATCAGTGATAAACCGCGTTTAAC
CACCCAAAAACTGTCACTGGGCTACGGCCAGCAACTTATTATCAATAAGCTTAGCCTGAGCATTAAAAACGGCGCGTTCA
GCGTCATTATCGGCCCAAACGGTTGTGGTAAATCGACGTTGTTGCGAGCGCTCAGCCGTAGCTTGTTACCACAAAATGGC
AGTATCAGGTTAGATCAACAGGATATTCAGCACTACAAAGCCAAGGTCTTTGCCCGCCAGTTATCGCTACTTTCTCAGGG
CGCAAGTATTTCTGAAACCTTGACCGTGTTTGATCTGGTTTCCCGTGGCCGTTACGCCCATCAATCATTCTTTCATCAAT
GGTCGACGGAAGATGAACGTATCGTAAAAGCCGCTATCAGCGCCGTTAATCTGGAGAGTCTGGTGCAGCAGAGAGTCAGT
GAACTCTCTGGTGGTCAGCGGCAACGTGCGTGGTTTGCCATGACACTGGCTCAACATACACCGATTGTTTTATTGGATGA
ACCGACCACATATTTGGATATCGCGCACCAAATTGAAATGCTGGATTTATGCCAAGAACTGCAACAACAGGGGAAAACGC
TGGTATTGGTGCTACACGATATTAATCAGGCTCTGCGTTATGCCACCCACCTGATTATGTTGAAAGAGGGGCAAATTTAT
GCAGAAGGTTTACCAGAATCTATCGTTACTGAAGACAGCATTGCCGCCGTTTTTGGGCTACGTTGCCGGATCATTACTGA
CCCTGAATCCGGCAAGCCTTTGGTGATACCCCGCCGTCAGTCGCGTTAG

Protein sequence : 
MRSQRELTSPMTPLENPGDISDKPRLTTQKLSLGYGQQLIINKLSLSIKNGAFSVIIGPNGCGKSTLLRALSRSLLPQNG
SIRLDQQDIQHYKAKVFARQLSLLSQGASISETLTVFDLVSRGRYAHQSFFHQWSTEDERIVKAAISAVNLESLVQQRVS
ELSGGQRQRAWFAMTLAQHTPIVLLDEPTTYLDIAHQIEMLDLCQELQQQGKTLVLVLHDINQALRYATHLIMLKEGQIY
AEGLPESIVTEDSIAAVFGLRCRIITDPESGKPLVIPRRQSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-49 47
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-49 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-45 45
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 8e-58 45
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 8e-58 45
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 7e-58 45
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-58 45
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-48 44
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-47 42
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-50 41
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-50 41
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-50 41
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-50 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ysuD NP_992786.1 iron-siderophore transport system, ATP-binding component BAC0164 Protein 1e-45 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ysuD NP_992786.1 iron-siderophore transport system, ATP-binding component VFG0925 Protein 2e-63 55
ysuD NP_992786.1 iron-siderophore transport system, ATP-binding component VFG1042 Protein 1e-45 45