Gene Information

Name : psaC (YP_1287)
Accession : NP_992653.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : outer membrane usher protein PsaC
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 1407327 - 1409840 bp
Length : 2514 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 psaC and Yersinia pestis KIM psaC. Contains Fimbrial biogenesis outer membrane usher protein (Interpro|IPR000015, (GO:0016020))

DNA sequence :
TTGAAAAAATTAATAGTTCAATTTACTACTATTACTCTATTGATGAGCACTTCATTTTTAGTGGGTGCCCAGCGTTATTC
TTTTGATCCCAATCTGCTAGTGGATGGCAATAACAACACTGATACCTCGTTATTTGAACAGGGCAATGAATTACCGGGCA
CCTATTTGGTGGATATTATCTTGAATGGGAATAAAGTGGACTCTACGAATGTGACATTTCATTCGGAGAAATCGCCATCA
GGAGAGCCTTTCTTGCAATCTTGCTTAACCAAGGAGCAGCTATCCCGCTATGGTGTGGATGTTGATGCCTATCCCGAGTT
ATCTCCAGCATTAAAAAACTCACAGACAAACCCGTGTGTCAATTTAGCCGCTATCCCTCAGGCCAGTGAAGAGTTCCAAT
TTTATAATATGCAGTTGGTACTGAGTATTCCACAAGCGGCTTTACGGCCTGAAGGTGAAGTGCCAATAGAACGCTGGGAT
GATGGTATTACGGCTTTTTTGCTGAACTACATGGCAAATATCAGTGAAACCCAGTTTCGTCAAAATGGTGGATACCGGCG
TTCACAATATATCCAGTTATATCCCGGTTTAAATTTGGGGGCGTGGCGTGTTCGTAATGCGACCAACTGGAGTCAATCTG
GCGATAGGGGGGGTAAATGGCAAAGTGCTTATACCTATGCCACTCGTGGGATTTATCGTTTAAAGAGCCGGGTGACCTTA
GGGGAGAGTTACACCCCAGGTGATTTTTTCGACAGCATTCCCTTTCGTGGCGTGATGTTGGGGGACGATCCTAATATGCA
GCCAAGTAACCAGCGGGATTTTATACCGGTGGTGCGTGGTATTGCCCGTAGTCAGGCGCAGGTGGAAATCAGACAAAATG
GTTATCTGATTTATAGTACGGTGGTGCCGCCGGGGCCGTTTGAACTCTCTGACGTGATCCCGAGTAAATCAGGCAGTGAC
CTACATGTTAGGGTGCTGGAAAGTAACGGGGCATCGCAGGCGTTTATTGTGCCTTATGAGGTGCCAGCCATTGCATTGCG
CAAAGGGCATTTGCGATACAATCTGGTGGCAGGGCAGTATCGCCCCGCCAATGCTGATGTTGAGACGCCTCCGGTCGCTC
AGGCAACCGTCGCCTACGGCTTGCCGTGGAACTTGACCGCATTTATCGGTGAGCAGTGGTCGCGGCATTATCAGGCAACC
TCTGCCGGATTAGGGGGGCTATTGGGGGAGTATGGCGCATTGTCATCCAGTATCACGCAGGCAACCAGTCAGTATCACCA
TCAACAACCGGTTAAAGGGCAAGCCTGGGAGGTTCGATACAACAAAACCTTACAAGCCTCTGATACGTCATTTTCATTGG
TGAATAGTCAATACAGCACTAATGGTTTCAGTACGTTATCTGATGTATTACAAAGTTACCGGCAGAGCGGGAGTGGCGAT
AATAGAGATAAAATTGACGAAAATTCTCGGTCAAGGGATTTGCGTAACCAAATCAGTGCGGTCATCGGGCAGTCATTGGG
CAAGTTTGGCTACCTGAACCTTAATTGGTCGCGGCAGGTCTACCGTGGGCCGATTCCGGCTAAGAATTCATTGGGAATAC
ACTATAACCTCAATGTCGGTAATAGTTTTTGGGCACTGAGTTGGGTGCAAAATGCGAATGAGAACAAGAATGATCGAATA
TTGAGTTTGTCTGTCAGTATTCCGCTGGGAGGTCATCACGATACTTATGCTTCCTATAGAATGACATCTTCCAACGGGAG
CAATGATCATGAGATAGGAATGTACGGCCAGGCTTTTGACTCTCGCTTGAGTTGGAGTGTGCGTCAGGCAGAGCATTATG
GTCAACCCAACTCAGGGCATAACAGCGGCTCACTCAGGTTGGGCTGGCAGGGTTCCTATGGCAATATCGCGGGAAATTAC
TACTATACTCCGAGCATACGTCAGTTATCCGCTGATGTTTCCGGAGGGGCGATCATCCATCGGCATGGGCTGACATTAGG
GCCGCAAATCAATGGCACCTCCGTGCTGGTTGAAGTTCCGGGCGTCGGCGGGGTGACCACCACAGAAGATCGCCGTCTGA
AAACAGATTTTCGCGGTTACAGCATTGTGTCTGGCCTCTCTCCTTATCAGGAGCACGATATCGTGTTGGAAACTGCAGAT
TTACCGCCGGATGCGGAGGTGGCAAAAACAGATACCAAGGTCTTGCCGACCGAGGGGGCGATTGTTCGTGCCAGTTTTAG
CCCGCAAATCGGGGCAAAGGCGCTGATGACGATCACCCGCGCTAATGGCCAAACCATTCCGTTTGGTGCGATGGCGAGCT
TGGTTAATCAGTCGGCCAATGCAGCCATTGTCGATGAAGGGGGGAAAGCCTATCTAACCGGGTTACCGGAAACAGGGCAG
TTATTGGTGCAATGGGGTAAAGATGCGGGCCAACAATGCCGGGTGGATTACCAGCTCTCGCCAGCGGAAAAAGGTGATAC
CGGGCTGTATATGCTCAGCGGAGTATGCCATTAA

Protein sequence :
MKKLIVQFTTITLLMSTSFLVGAQRYSFDPNLLVDGNNNTDTSLFEQGNELPGTYLVDIILNGNKVDSTNVTFHSEKSPS
GEPFLQSCLTKEQLSRYGVDVDAYPELSPALKNSQTNPCVNLAAIPQASEEFQFYNMQLVLSIPQAALRPEGEVPIERWD
DGITAFLLNYMANISETQFRQNGGYRRSQYIQLYPGLNLGAWRVRNATNWSQSGDRGGKWQSAYTYATRGIYRLKSRVTL
GESYTPGDFFDSIPFRGVMLGDDPNMQPSNQRDFIPVVRGIARSQAQVEIRQNGYLIYSTVVPPGPFELSDVIPSKSGSD
LHVRVLESNGASQAFIVPYEVPAIALRKGHLRYNLVAGQYRPANADVETPPVAQATVAYGLPWNLTAFIGEQWSRHYQAT
SAGLGGLLGEYGALSSSITQATSQYHHQQPVKGQAWEVRYNKTLQASDTSFSLVNSQYSTNGFSTLSDVLQSYRQSGSGD
NRDKIDENSRSRDLRNQISAVIGQSLGKFGYLNLNWSRQVYRGPIPAKNSLGIHYNLNVGNSFWALSWVQNANENKNDRI
LSLSVSIPLGGHHDTYASYRMTSSNGSNDHEIGMYGQAFDSRLSWSVRQAEHYGQPNSGHNSGSLRLGWQGSYGNIAGNY
YYTPSIRQLSADVSGGAIIHRHGLTLGPQINGTSVLVEVPGVGGVTTTEDRRLKTDFRGYSIVSGLSPYQEHDIVLETAD
LPPDAEVAKTDTKVLPTEGAIVRASFSPQIGAKALMTITRANGQTIPFGAMASLVNQSANAAIVDEGGKAYLTGLPETGQ
LLVQWGKDAGQQCRVDYQLSPAEKGDTGLYMLSGVCH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 2e-176 46
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 4e-162 44
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 5e-160 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
psaC NP_992653.1 outer membrane usher protein PsaC VFG0853 Protein 2e-160 43
psaC NP_992653.1 outer membrane usher protein PsaC VFG0944 Protein 3e-157 42
psaC NP_992653.1 outer membrane usher protein PsaC VFG0849 Protein 4e-148 41
psaC NP_992653.1 outer membrane usher protein PsaC VFG0857 Protein 1e-142 41