Gene Information

Name : metC1 (YP_0117)
Accession : NP_991519.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 122891 - 124132 bp
Length : 1242 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGTCCAGATGTATTGACGTCCGTAATTTGTGCGTCTACTCTGGCGTAACATTTTCTCGATCCCGGCTGGTGGAAATCAA
TATGACGCGTAAACAGGCAACAATAGCAGTCCGTAGCGGGTTGAATGATGACGAGCAATACGGCTGCGTTGTCCCCCCGA
TTCACCTTTCCAGTACCTACAATTTTATTGATTTTAATCAGCCGCGCACGCATGACTATTCACGTCGTGGTAATCCAACG
CGTGATGTTGTCCAACGGGCGCTGGCGGAATTGGAAGGGGGGGCCGGTGCCGTCATGACCAGCAGCGGGATGTCGGCGCT
TCATTTGGTTTGCACTACATTCTTACAGCCGGGCGATCTGTTGGTCGCTCCGCATGACTGTTACGGTGGCAGTTACCGTT
TATTTGACAGCTTGAGCAAGCGTGGTGCGTATCGGGTGTTATTTGTTGATCAGGGCGATGAAGCGGCACTAAACTGCGCA
TTGGCGGAGAAACCGAAGTTGGTCTTGATTGAAACACCGAGTAATCCATTGCTACGGGTTGTTGATATTGCCGCCATCTG
CCAAGCCGCCCGTGCTGCGGGCGCACTGACGGTTTGTGATAACACCTTCCTCAGCCCCGCCTTACAGCAGCCTCTCTCTC
TTGGGGCCGATTTAGTGGTGCACTCCTGTACCAAATATCTCAATGGTCACTCTGATGTGGTGGCTGGTGCTGTTATTGCG
AAAGATCCAGAACTGGTTGTCGAGCTGGCATGGTGGGCAAATAATATTGGTGTAACCGGTGCTGCGTTTGACAGCTATCT
ACTCCTTCGTGGTTTACGCACGTTATCACCACGCATGGCTCAACAGCAGCGTAACGCGGATGACATTGTGCGTTATTTAC
AGCAACAGCCTTTAGTGAAAAAGCTGTATCATCCTTCCCTGCCACAACATCCCGGCCACGAAATAGCCTGCCGTCAGCAA
TCAGGTTTTGGTGCAATGCTCAGTTTTGAGCTGGATGGTGATGAGCAGGTCATGCGCCGTTTCCTTTCTGCCCTTGAGCT
ATTTACCTTGGCAGAGTCTTTGGGGGGGGTAGAAAGCCTGATCTCCCATGCAGCGACCATGACCCACGCGGGTATGGCGG
CAGAGGCGCGTATTGCCGCAGGCATTACTGATAGTTTGTTGCGTATTTCCGTGGGTATTGAAGACAGTGAAGATTTGATT
GCTGATTTGGACCACGCGTTCCAATTGGCAGTAACGAGGTAA

Protein sequence :
MSRCIDVRNLCVYSGVTFSRSRLVEINMTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFIDFNQPRTHDYSRRGNPT
RDVVQRALAELEGGAGAVMTSSGMSALHLVCTTFLQPGDLLVAPHDCYGGSYRLFDSLSKRGAYRVLFVDQGDEAALNCA
LAEKPKLVLIETPSNPLLRVVDIAAICQAARAAGALTVCDNTFLSPALQQPLSLGADLVVHSCTKYLNGHSDVVAGAVIA
KDPELVVELAWWANNIGVTGAAFDSYLLLRGLRTLSPRMAQQQRNADDIVRYLQQQPLVKKLYHPSLPQHPGHEIACRQQ
SGFGAMLSFELDGDEQVMRRFLSALELFTLAESLGGVESLISHAATMTHAGMAAEARIAAGITDSLLRISVGIEDSEDLI
ADLDHAFQLAVTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-53 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-52 43