Gene Information

Name : leuS (YP_1103)
Accession : NP_992472.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1185466 - 1188048 bp
Length : 2583 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGCCCAGAAGATATCGAAACGCAAGTACAGCTTCACTGGCAAGAGAAGCAAACCTTTAAAGTCAC
TGAAGACGCCAGCAAAGAAAAATATTATTGCCTATCTATGCTGCCATACCCTTCAGGACGCCTGCATATGGGGCACGTTC
GTAATTACACCATTGGCGACGTTATCTCTCGTTACCAGCGTATGTTGGGCAAAAACGTCTTGCAGCCAATTGGCTGGGAT
GCGTTTGGCCTGCCCGCTGAAGGGGCTGCGGTAAAAAACAATACCGCCCCCGCACCTTGGACTTACGACAACATCGAATA
CATGAAGAACCAGTTGAAATTACTGGGCTTCGGCTATGACTGGGATCGAGAAATTGCCACCTGCAAACCTGATTATTATC
GTTGGGAGCAGTGGTTCTTCACCAAGTTGTATGAAAAAGGAATGGTCTACAAGAAGACCTCTGCGGTTAACTGGTGTCCA
CACGATCTCACTGTGCTGGCTAACGAGCAGGTCATTGACGGCTGCTGCTGGCGTTGTGACACCAAAGTTGAACGTAAAGA
GATCCCGCAGTGGTTTATCAAAATCACCGATTACGCTGAGCAGTTGCTCAACGATCTGGACACGCTGGAAAGCTGGCCAG
AGCAGGTGAAAACCATGCAACGTAACTGGATTGGCCGCTCTGAAGGGGTCGATATCGTTTTCGACGTCGTGGATAGCGAA
GAGAAACTGTCTGTTTATACCACCCGGCCAGACACCTTTATGGGCGTGACCTACGTAGCGGTTGCTGCTGGTCATCCTTT
GTCATTGCAAGCGGCGGCGACTAATCCGGCCCTGGCTGATTTCGTTGCTGAATGCCGTAATACCAAGGTTGCCGAAGCTG
AAATGGCAACCATGGAGAAAAAAGGCATGGCGACGGGTCTGTATGCCATCCATCCATTAACTGGCGAGAAACTGCCTATA
TGGGCCGCTAACTTTGTCTTGATGGATTACGGTACTGGCGCAGTGATGGCCGTTCCGGGCCACGATGCACGTGACTGGGA
ATTTGCCACCAAATATAACCTGCCAATCAAACCGGTTATTTTGGCCGCGGATGGCAGTGAGCCAGACTTGAGTCAGGAAG
CCATGACCGAGAAAGGCACGCTGTTTAACTCTGGTGAGTTTGATGGCCTGAATCATGAAGATGGTTTTAATGCCATTGCC
GATAAACTGGTCGCACTCGGTGTTGGGCAGCGCAAAGTAAACTATCGTCTGCGTGACTGGGGTGTTTCTCGCCAGCGTTA
TTGGGGTGCCCCGATCCCAATGGTTACGTTGGAAGATGGGACTGTCGTTCCTACCCCAGAAGATCAACTGCCGGTTATCC
TGCCAGAAGATGTGGTAATGGACGGTATTTCCAGCCCGATCAAGGCCGATCCTGAGTGGGCTAAAACCACCGTTAACGGT
ATTCCGGGTCTGCGTGAAACCGATACCTTCGATACCTTTATGGAATCATCTTGGTATTACGCGCGCTACACCTGCCCGCA
ATATGATGACGGTATGCTGGACCCCGCAGCCGCTAACTACTGGTTACCTGTCGATCAGTATGTTGGGGGCATTGAACATG
CCATTATGCATCTGATGTATTTCCGCTTCTTCCACAAATTACTGCGTGACGCCGGTCTGGTGGACTCCGATGAACCCGCC
AAACGCCTGTTATGTCAGGGGATGGTACTGGCTGACGCCTTCTATTACACCGGTAATAACGGTGAGCGTATTTGGGTTTC
ACCGGTCGATGCGATTGTCGAACGTGATGACAAAGGCCGTATCGTTAAAGCTGTAGATGCGGAAGGCCATGAGCTGGTGT
ACGCCGGCATGAGTAAAATGTCGAAATCGAAAAACAACGGTATCGACCCGCAAGTCATGGTAGAAAAATACGGCGCGGAT
ACCGTACGTCTGTTTATGATGTTTGCCTCACCAGCAGAAATGACGCTGGAATGGCAGGAGTCGGGCGTTGAAGGGGCTAA
CCGCTTCCTGAAGCGTGTTTGGCGTCTGGCCTTTGATCACACCGCGAAAGGTGCAGTGAAGCCACTGGATATTGCCAGCC
TGACTGAAGAACAGAAATCCCTGCGTCGCGACCTGCATAAAACCATTGCGAAAGTGACCGATGATGTTGGCCGCCGTCAA
ACCTTCAACACGGCAATTGCTGCTGTGATGGAGTTGATGAACAAGCTGGGCCGTGCACCTCAGGAAACGGAGCAAGACCG
CGCACTGATGCAAGAAGCTTTACTGGCGGTAGTCCGGATGCTTTATCCATTCACCCCTCACGTCTGCTTCAGTTTGTGGC
AAGCTTTGGGTGGAGAAGGCGATATCGATACTGCGCCGTGGCCAATTGCTGATGAACAAGCGATGGTTGAAGACTCTAAA
TTAGTGGTCGTACAGGTCAATGGCAAAGTGCGTGGCAGAATTACAGTGCCCGCCGATGCCACTGAACAGCAAGTCCGTGA
ACGCGCTGGTCAGGAGCACTTGGTGGCTAAATATCTGGATGGCGTTACTGTACGTAAAGTCATCTATGTCCCTGGCAAAT
TGCTTAATCTGGTTGTGGGTTAA

Protein sequence :
MQEQYRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDREIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCP
HDLTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSE
EKLSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMATMEKKGMATGLYAIHPLTGEKLPI
WAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKPVILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIA
DKLVALGVGQRKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILPEDVVMDGISSPIKADPEWAKTTVNG
IPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHAIMHLMYFRFFHKLLRDAGLVDSDEPA
KRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVERDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTDDVGRRQ
TFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQALGGEGDIDTAPWPIADEQAMVEDSK
LVVVQVNGKVRGRITVPADATEQQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-158 42