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Name : leuS (YP_1103) Accession : NP_992472.1 Strain : Yersinia pestis 91001 Genome accession: NC_005810 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1185466 - 1188048 bp Length : 2583 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAGCAATACCGCCCAGAAGATATCGAAACGCAAGTACAGCTTCACTGGCAAGAGAAGCAAACCTTTAAAGTCAC TGAAGACGCCAGCAAAGAAAAATATTATTGCCTATCTATGCTGCCATACCCTTCAGGACGCCTGCATATGGGGCACGTTC GTAATTACACCATTGGCGACGTTATCTCTCGTTACCAGCGTATGTTGGGCAAAAACGTCTTGCAGCCAATTGGCTGGGAT GCGTTTGGCCTGCCCGCTGAAGGGGCTGCGGTAAAAAACAATACCGCCCCCGCACCTTGGACTTACGACAACATCGAATA CATGAAGAACCAGTTGAAATTACTGGGCTTCGGCTATGACTGGGATCGAGAAATTGCCACCTGCAAACCTGATTATTATC GTTGGGAGCAGTGGTTCTTCACCAAGTTGTATGAAAAAGGAATGGTCTACAAGAAGACCTCTGCGGTTAACTGGTGTCCA CACGATCTCACTGTGCTGGCTAACGAGCAGGTCATTGACGGCTGCTGCTGGCGTTGTGACACCAAAGTTGAACGTAAAGA GATCCCGCAGTGGTTTATCAAAATCACCGATTACGCTGAGCAGTTGCTCAACGATCTGGACACGCTGGAAAGCTGGCCAG AGCAGGTGAAAACCATGCAACGTAACTGGATTGGCCGCTCTGAAGGGGTCGATATCGTTTTCGACGTCGTGGATAGCGAA GAGAAACTGTCTGTTTATACCACCCGGCCAGACACCTTTATGGGCGTGACCTACGTAGCGGTTGCTGCTGGTCATCCTTT GTCATTGCAAGCGGCGGCGACTAATCCGGCCCTGGCTGATTTCGTTGCTGAATGCCGTAATACCAAGGTTGCCGAAGCTG AAATGGCAACCATGGAGAAAAAAGGCATGGCGACGGGTCTGTATGCCATCCATCCATTAACTGGCGAGAAACTGCCTATA TGGGCCGCTAACTTTGTCTTGATGGATTACGGTACTGGCGCAGTGATGGCCGTTCCGGGCCACGATGCACGTGACTGGGA ATTTGCCACCAAATATAACCTGCCAATCAAACCGGTTATTTTGGCCGCGGATGGCAGTGAGCCAGACTTGAGTCAGGAAG CCATGACCGAGAAAGGCACGCTGTTTAACTCTGGTGAGTTTGATGGCCTGAATCATGAAGATGGTTTTAATGCCATTGCC GATAAACTGGTCGCACTCGGTGTTGGGCAGCGCAAAGTAAACTATCGTCTGCGTGACTGGGGTGTTTCTCGCCAGCGTTA TTGGGGTGCCCCGATCCCAATGGTTACGTTGGAAGATGGGACTGTCGTTCCTACCCCAGAAGATCAACTGCCGGTTATCC TGCCAGAAGATGTGGTAATGGACGGTATTTCCAGCCCGATCAAGGCCGATCCTGAGTGGGCTAAAACCACCGTTAACGGT ATTCCGGGTCTGCGTGAAACCGATACCTTCGATACCTTTATGGAATCATCTTGGTATTACGCGCGCTACACCTGCCCGCA ATATGATGACGGTATGCTGGACCCCGCAGCCGCTAACTACTGGTTACCTGTCGATCAGTATGTTGGGGGCATTGAACATG CCATTATGCATCTGATGTATTTCCGCTTCTTCCACAAATTACTGCGTGACGCCGGTCTGGTGGACTCCGATGAACCCGCC AAACGCCTGTTATGTCAGGGGATGGTACTGGCTGACGCCTTCTATTACACCGGTAATAACGGTGAGCGTATTTGGGTTTC ACCGGTCGATGCGATTGTCGAACGTGATGACAAAGGCCGTATCGTTAAAGCTGTAGATGCGGAAGGCCATGAGCTGGTGT ACGCCGGCATGAGTAAAATGTCGAAATCGAAAAACAACGGTATCGACCCGCAAGTCATGGTAGAAAAATACGGCGCGGAT ACCGTACGTCTGTTTATGATGTTTGCCTCACCAGCAGAAATGACGCTGGAATGGCAGGAGTCGGGCGTTGAAGGGGCTAA CCGCTTCCTGAAGCGTGTTTGGCGTCTGGCCTTTGATCACACCGCGAAAGGTGCAGTGAAGCCACTGGATATTGCCAGCC TGACTGAAGAACAGAAATCCCTGCGTCGCGACCTGCATAAAACCATTGCGAAAGTGACCGATGATGTTGGCCGCCGTCAA ACCTTCAACACGGCAATTGCTGCTGTGATGGAGTTGATGAACAAGCTGGGCCGTGCACCTCAGGAAACGGAGCAAGACCG CGCACTGATGCAAGAAGCTTTACTGGCGGTAGTCCGGATGCTTTATCCATTCACCCCTCACGTCTGCTTCAGTTTGTGGC AAGCTTTGGGTGGAGAAGGCGATATCGATACTGCGCCGTGGCCAATTGCTGATGAACAAGCGATGGTTGAAGACTCTAAA TTAGTGGTCGTACAGGTCAATGGCAAAGTGCGTGGCAGAATTACAGTGCCCGCCGATGCCACTGAACAGCAAGTCCGTGA ACGCGCTGGTCAGGAGCACTTGGTGGCTAAATATCTGGATGGCGTTACTGTACGTAAAGTCATCTATGTCCCTGGCAAAT TGCTTAATCTGGTTGTGGGTTAA Protein sequence : MQEQYRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWD AFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDREIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCP HDLTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSE EKLSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMATMEKKGMATGLYAIHPLTGEKLPI WAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKPVILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIA DKLVALGVGQRKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILPEDVVMDGISSPIKADPEWAKTTVNG IPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHAIMHLMYFRFFHKLLRDAGLVDSDEPA KRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVERDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTDDVGRRQ TFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQALGGEGDIDTAPWPIADEQAMVEDSK LVVVQVNGKVRGRITVPADATEQQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 6e-158 | 42 |
