Gene Information

Name : intA1 (YP_1057)
Accession : NP_992430.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Unknown
Product : prophage CP4-57 integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1138213 - 1139445 bp
Length : 1233 bp
Strand : +
Note : highly similar to Yersinia pestis KIM intA. Contains Phage integrase (Interpro|IPR002104, (GO:0015074))

DNA sequence : 
ATGGACGTATACCAATTAAGGGAAGAACCATACATGGCAAGGACAACACGCCCCCTCACCCACACCGAAGTACAAAAAGC
AAAAGCCACCGACAAAGACCTAACCCTCCATGATGGTGATGGTTTATTTTTGCTAGTCAAAACTACCGGCAAGAAAATTT
GGCGTTTCCGCTATCAGCTTCCCAACAGTAGCAAGCGCACTATGATCAGCCTCGGTGCTTACCCAGCACTATCCCTCGCA
GATGCCAGAGAGATACGCGCAGAAAAACTAGCGATGTTAGTCAGAGGGACAGACCCTCAAACGAGGGCTGGTGAAGAGGC
TGAAAAGCTCCAGATAGCGGAGGAAAGCATTTTTGTGAATGTCGCCCGCAAATGGTTCGAGTTGAAAGAAAGCCATGTTA
GCGCAGCCCATGCGAAAGATATTTGGCGTTCTATTGAAAAAGACATCTTACCCAGCATCGAAAATATTCCCATCCAAGAA
CTTAAAGCACGAACTCTGATTCAAGTATTGGAGCCAATCAAAGCACGTGGAGCATTAGAGACGGTCAGGCGATTGGTACA
ACGTATAAACGAGATAATGATCTATGCGGTCAATGTAGGTTTGATTGATGCTAACCCAGCTTCAGGTATCGGTAATGCTT
TTGAACGCCCCAAGAAGCAGCATATGCCCACCATCAGACCTGAAGAACTACCTAAACTCATGCGTACCATTGCCATGAGC
AATCTCTCACTGCCAACCCGCTGCTTACTTGAATGGCAATTACTAACTCTGATACGCCCCGCTGAAGCATCAGCAACAGC
TTGGATAGAGATCGATTTAGAGAATAAGCAGTGGTGTATACCGGCAGAACGAATGAAAGCAAAGCGCGACCATATAGTCC
CGTTGTCGGAACAAGCCTTAGAGTTGCTGGAAATAATGCGTCCAATTAGTGGTAATCGTCAGCACGTATTCCCAAGTCGC
AATGACCCACGTAATCACATGAATAGCCAAACAGCAAATGCAGCCTTGAAACGTATTGGTTATGGAGGGAAGCTCGTTGC
TCACGGTTTACGTTCTATCGCCAGTACAGCCATGAATGAGGCTGGGTTTAATGCTGATGTGATTGAGGCTGCGCTAGCGC
ATAGTGATAAGAATGAAGTCAGGAAAGCTTATAATCGTTCTACCTATCTCATACAACGCCAAGAGTTAATGAATTGGTGG
GGATTAGAGATATACACTAAAAGAAGTATTTAA

Protein sequence : 
MDVYQLREEPYMARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLA
DAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQE
LKARTLIQVLEPIKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMS
NLSLPTRCLLEWQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSR
NDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWW
GLEIYTKRSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0516 NP_230167.1 phage integrase Not tested VSP-2 Protein 3e-102 53
VC0847 NP_230494.1 phage family integrase Not tested VPI-1 Protein 3e-97 50
VC0395_A0372 YP_001216328.1 phage family integrase Not tested VPI-1 Protein 3e-97 50
int AAK20773.1 integrase Not tested VPI Protein 2e-97 50
int AAK20803.1 integrase Not tested VPI Protein 2e-97 50
unnamed AAA82714.1 integrase Not tested VPI Protein 2e-97 50
VPI2_0001 ACA01818.1 phage family integrase Not tested VPI-2 Protein 3e-85 46
VC1758 NP_231394.1 phage family integrase Not tested VPI-2 Protein 6e-85 46
VC0395_A1357 YP_001217300.1 phage family integrase Not tested VPI-2 Protein 6e-85 46
int AAD44730.1 Int Not tested SHI-2 Protein 3e-66 42
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 9e-65 41
ECs4534 NP_312561.1 integrase Not tested LEE Protein 9e-65 41
int AAC31482.1 CP4-like integrase Not tested LEE Protein 7e-65 41
int ACU09430.1 integrase Not tested LEE Protein 7e-65 41
int CAC39282.1 integrase Not tested LPA Protein 7e-65 41
aec33 AAW51716.1 Int Not tested AGI-3 Protein 4e-65 41
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 6e-65 41
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 6e-65 41
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 5e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intA1 NP_992430.1 prophage CP4-57 integrase VFG1092 Protein 3e-85 46
intA1 NP_992430.1 prophage CP4-57 integrase VFG0783 Protein 4e-65 41
intA1 NP_992430.1 prophage CP4-57 integrase VFG0598 Protein 3e-65 41