Gene Information

Name : irp5 (PSPPH_2902)
Accession : YP_275084.1
Strain : Pseudomonas syringae 1448A
Genome accession: NC_005773
Putative virulence/resistance : Virulence
Product : yersiniabactin synthetase, salycilate ligase component Irp5
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 6.3.2.-
Position : 3369443 - 3371011 bp
Length : 1569 bp
Strand : +
Note : identified by similarity to GB:AAO56101.1; match to protein family HMM PF00501

DNA sequence : 
ATGCACACCGAACTTGCCTTCAAAGACCCGCTACACCCCTTCGCCGACCAGACCCTCCCTCAACGCTTGCGTCGATGGGC
AAGCCAGCACGGCTCACGCACAGCGCTGGTCGCAGGTGCCGTACGCGTGAGCTATGCGCAACTGGACCTGCGAGTCGACC
GCCTGGCCGGCGGCCTTGGCGCGCTGGGCATAAAAGCCGGTGACAGGGTGATGCTGCAACTGCCCAACGGCGTCGGCTTT
GTCTGCGCATTCTTTGCCGTAATGCGCATCGGTGCGGTGCCGGTATTGGCCATGCCCACTCAGCGTGCAGAGGACATCGC
GGCACTTTGCCGGTTGGCAGACCCCGTGGCCTACCTGATTCCCGATCGCCTTCGGGACTTCGATTTTCGCGAGATGGCCG
CCGGGATTATCGAGCACCAGCCCTCACTGGCGCATGTCATTGTCGACGGCGAACACGGACCTTTCAAAGCGCTGTCGGCG
CTGGATGCACCCTGCCCGGCGGACCCGCTGGCAGACCCGCGCGGTATGGCCTTGCTGCTGCTTTCAGGTGGCACCACCGG
CACCCCGAAACTGATTCCGCGCAGCCACGCCGACTACGCCTACAATTTTTCTCATTCAGCCAGGCTCTGCGAACTGGACA
GCAACAGCGTGTACCTGGCGGTGTTGCCGACCGCGCACAATTTCACCCTCGCCTGCCCCGGCGTACTGGGCAGCCTGGCC
GCAGGTGCAACCGTGGTACTGGGTGACAGCGCCAGTTGCGATGCAGCCATGCCCCTGATCGAACGTGAAGGTGTCACCCA
TGTGGCGCTGGTCCCTCCGCTGGCGCAACTCTGGGCCCAGGGGCGCGACTGGGAAGACAGCGATCTGTCCAGCCTGAAGC
TGCTGCAGGTGGGTGGATCTCGACTGGACCCGGCGCTCGCTACAGATGTGCTTGATGCGCTGGATTGCCGAGTGCAGCAG
GTGTTCGGCATGGCCGAGGGTCTGCTGTGCTATACCCGGCCGGACGATCCGCTGGAGGTCGTGCTCAACACCCAGGGTCG
TCCACTGTCACCGTTCGACGAGGTTCGTCTGGTGGACGCCGACCTGCACGACGTCGCTCCCGGCCAGACCGGTGAACTGC
TGACCCGCGGCCCGTACACCATTACCGGGTATTACCAGGCGGCAGAACACAACGCGCGCAGCTTCACCCACGACGGTTAC
TACCGCAGCGGCGACCTTGCGCGCTGGACGCCCGAAGGCAACCTGATCGTCGAAGGACGTATCAAGGAACAGATCCAGCG
CAGCGGTGAAAAGATCTCGGCAGCACACATAGAAAACCACCTTGCCGCCCTGCCCGACATTGATTCTGCCGTAGTGGTCG
CCGTGCCGGATGCGCTGCTGGGCGAGCGCATTTGCGCGTTCATCCTGGGCGAACAGCCTGCCGGCGCGGCTCAATACGTG
CGCGACCAACTGCGTCTGCAGGGGCTGGGCGAGGACAGCCTGCCCGATCAGTTCGAGTGGGTTGCTGCGTGGCCACTGAC
CGCTGTGGGCAAGATCGACAAACGTCAACTGGCCGTTATGGCCCAGTGA

Protein sequence : 
MHTELAFKDPLHPFADQTLPQRLRRWASQHGSRTALVAGAVRVSYAQLDLRVDRLAGGLGALGIKAGDRVMLQLPNGVGF
VCAFFAVMRIGAVPVLAMPTQRAEDIAALCRLADPVAYLIPDRLRDFDFREMAAGIIEHQPSLAHVIVDGEHGPFKALSA
LDAPCPADPLADPRGMALLLLSGGTTGTPKLIPRSHADYAYNFSHSARLCELDSNSVYLAVLPTAHNFTLACPGVLGSLA
AGATVVLGDSASCDAAMPLIEREGVTHVALVPPLAQLWAQGRDWEDSDLSSLKLLQVGGSRLDPALATDVLDALDCRVQQ
VFGMAEGLLCYTRPDDPLEVVLNTQGRPLSPFDEVRLVDADLHDVAPGQTGELLTRGPYTITGYYQAAEHNARSFTHDGY
YRSGDLARWTPEGNLIVEGRIKEQIQRSGEKISAAHIENHLAALPDIDSAVVVAVPDALLGERICAFILGEQPAGAAQYV
RDQLRLQGLGEDSLPDQFEWVAAWPLTAVGKIDKRQLAVMAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-124 57
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-123 57
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-124 57
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-122 57
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-122 57
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-122 57
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-122 57
ybtE CAA21394.1 - Virulence HPI Protein 1e-122 57
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-122 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp5 YP_275084.1 yersiniabactin synthetase, salycilate ligase component Irp5 VFG0168 Protein 2e-100 50
irp5 YP_275084.1 yersiniabactin synthetase, salycilate ligase component Irp5 VFG1817 Protein 4e-93 49
irp5 YP_275084.1 yersiniabactin synthetase, salycilate ligase component Irp5 VFG0932 Protein 7e-74 43