Gene Information

Name : guaA (PSPPH_1334)
Accession : YP_273592.1
Strain : Pseudomonas syringae 1448A
Genome accession: NC_005773
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1545226 - 1546803 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCTCGACATTCACGCCCACCGTATCCTGATCCTCGACTTCGGTTCCCAGTACACCCAGCTGATCGCCCGCCGCGT
GCGTGAAATCGGCGTGTACTGCGAGCTGCATCCGTTTGACATGGACGACGAAGCGATTCGCGAATTCGCTCCAAAAGGCG
TGATCCTCGCCGGCGGCCCCGAGTCCGTACACGAAGCTAACAGCCCACGCTGCCCGCAAGCAGTATTTGACCTGGGTGTG
CCGGTGTTCGGTATCTGCTACGGCATGCAGACCATGGCCGAGCAGTTGGGCGGCAAGGTTGCCGGTTCCGAGCTGCGCGA
GTTCGGCTACGCTCGCGTTGACGTAGTCGGCAAAAGCCGTCTGCTCGATGGTATCGAAGACCATATCGACGCCGACGGCC
TGTTTGGCCTCGACGTATGGATGAGTCACGGTGACAAGGTCACCAAACTGCCGGAAGACTTCCACATTCTGGCCAGTACC
CCGAGCTGCCCGATTGCCGGTATGGCTGATGACGCCCGCGGTTACTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CAAGCAGGGCGGTCGCATCCTGTCGCGCTTCATCCTCGACATCTGCGGCTGTGAAGCGCTGTGGACCCCGTCGAAGATTG
CTGAAGACGCTATCGCTCAGGTTCGCGCCCAGGTAGGCACCGACAACGTCCTGCTGGGCCTGTCCGGCGGCGTTGACTCG
TCTGTCGTTGCCGCGTTGCTGCACAAGGCCATCGGCGATCAACTGACCTGCGTATTCGTCGACAACGGCCTGCTGCGCCT
GCATGAAGGCGAGCAAGTGATGGCCATGTTCGCCGAGAACATGGGCGTCAAGGTGATCCGCGCCAATGCCGAAGAGCAGT
TCCTGAACAACCTGGAAGGCGAGAGCGACCCAGAGAAGAAGCGCAAGATCATCGGCCGTACCTTCATCGACGTGTTCGAT
GCCGAGTCCTGCAAGCTGGACAACATCAAATACCTGGCGCAAGGCACCATCTACCCGGACGTCATCGAGTCCGCTGGCGC
GAAAAGCGGCAAGGCCCACGTCATCAAGTCGCACCACAACGTGGGCGGCCTGCCGGAAGAAATGAACCTCAAGCTGGTCG
AGCCACTGCGCGAGCTGTTCAAGGACGAAGTCCGCCGCCTGGGCCTCGAACTCGGCCTGCCGTACGACATGGTCTACCGC
CACCCATTCCCAGGCCCAGGCCTGGGCGTGCGCATCCTCGGCGAAGTGAAGAAGGAATACGCCGACCTACTGCGTCGTGC
CGACCACATCTTCATCGAAGAACTGCGCAAGGCCGACTGGTATCACAAAGTCAGCCAGGCGTTCGTGGTGTTCCAGCCGG
TCAAATCGGTTGGCGTCGTCGGCGACGGCCGCCGCTACGCCTGGGTCGTCGCACTGCGTGCGGTGGAAACCATCGACTTC
ATGACCGCTCGTTGGGCGCACCTGCCTTATGAGCTGCTGGAGACGGTGAGTGGCCGGATCATCAATGAGATCGAAGGGAT
TTCGCGGGTGACGTATGACGTGTCGAGCAAGCCGCCGGCTACTATTGAGTGGGAATGA

Protein sequence :
MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFAPKGVILAGGPESVHEANSPRCPQAVFDLGV
PVFGICYGMQTMAEQLGGKVAGSELREFGYARVDVVGKSRLLDGIEDHIDADGLFGLDVWMSHGDKVTKLPEDFHILAST
PSCPIAGMADDARGYYGVQFHPEVTHTKQGGRILSRFILDICGCEALWTPSKIAEDAIAQVRAQVGTDNVLLGLSGGVDS
SVVAALLHKAIGDQLTCVFVDNGLLRLHEGEQVMAMFAENMGVKVIRANAEEQFLNNLEGESDPEKKRKIIGRTFIDVFD
AESCKLDNIKYLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRRLGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADLLRRADHIFIEELRKADWYHKVSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDF
MTARWAHLPYELLETVSGRIINEIEGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-127 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-127 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-112 48