Gene Information

Name : cks (Bd0807)
Accession : NP_967763.1
Strain : Bdellovibrio bacteriovorus HD100
Genome accession: NC_005363
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 756879 - 757622 bp
Length : 744 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAATTGTCGGTGTGATCCCCGCTCGTTTTGGCTCTACACGCTTCCCCGGAAAACCCCTGGTGAACTTGAAAGGCCG
CCCCCTGATTCAGTGGACGGTTGAAGGAGCCAAGAAGTCGAAACTTCTGAGCGAGGTGATTGTCGCCACCGATCACGAAG
GCATCAAAGCCGCCGCCGAAGCTGTCGGTGTTAAAGTCGTCATGACGGACAGCGATCTTCCCACCGGAAGCGACCGAATC
AATGCTGCCATTAAAGATGTTGCCTGTGATGTCGTTGTCAATATCCAGGGGGATGAACCGCTGGTGACCGGCGAGTTGAT
TGACCGCCTGGCGCAGGTGTTTGTCGATGATCCGAAAATGGACATGGCCACGCTGGCTCATCCGATCAGTGCTGAAGAGC
TGCAATCCATGAACTCGGTGAAAGTTGTTGTGAACTGCCGTGACGAGGCTCTTTATTTCAGCCGCTATCCAATGCCTTAT
TCCCGTATGTCGGCACAAGAGGCCGGCAGCATGGATGGTTGTCTGAAACACATCGGCATGTATGCCTATTCCAGAAATTT
TTTAAAACAGTTCTGCGAAGCTCCTCCGGCCCTCATTGAAAAAGCCGAGAGTCTGGAGCAGCTGCGCGCTCTGTATTTAG
GTGCAAAAATCAAAGTAATCAGAGTCAAGGAAGCCAGTGTCGGGGTGGATACTCCCGAAGATCTGGCGCGACTCGAAAAA
CTCTTAAGCTCACAGGGGATGTAA

Protein sequence :
MKIVGVIPARFGSTRFPGKPLVNLKGRPLIQWTVEGAKKSKLLSEVIVATDHEGIKAAAEAVGVKVVMTDSDLPTGSDRI
NAAIKDVACDVVVNIQGDEPLVTGELIDRLAQVFVDDPKMDMATLAHPISAEELQSMNSVKVVVNCRDEALYFSRYPMPY
SRMSAQEAGSMDGCLKHIGMYAYSRNFLKQFCEAPPALIEKAESLEQLRALYLGAKIKVIRVKEASVGVDTPEDLARLEK
LLSSQGM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-38 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-38 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-38 43