Gene Information

Name : thyA (Bd3230)
Accession : NP_969988.1
Strain : Bdellovibrio bacteriovorus HD100
Genome accession: NC_005363
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3148009 - 3148803 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGCAGTATCACGATCTCATCAAAACAGTTCTAGAACATGGCGTGAAAAAAGAGGACCGCACAGGCACCGGCACTAT
TTCCATGTTCGGTTATCAGATGCGCTACAATCTGCAAGAGGGCTTCCCTCTGCTGACCACCAAAAAACTGCACACGCGCT
CGATCTTTCATGAACTGCTGTGGTTCCTGAAGGGTGAAACCAACATCAAGTATCTTCACGACAACAAAGTGACGATCTGG
GATGAATGGGCTGATGAAAACGGCAACCTGGGCCCGGTGTACGGAAAACAATGGCGCTCCTGGGAAACGGCCGACGGCCG
CACCATCGATCAGATCACCAACGTCGTAGAGCAAATCAAAAAGAATCCGAACTCCCGCCGCATGCTGGTGGTGGCGTTCA
ATCCGGGCGACGTTGACAAGATGGCTTTGCCGCCATGTCACGCCTTCTTCCAGTTCTATGTGGCGAACGGAAAGCTTTCC
TGCCAGCTGTATCAGCGCAGTGCTGATATCTTCCTGGGCGTGCCGTTCAATATCGCCAGCTACGCTTTGCTGACCCATAT
GATCGCGCAAGTTTGTGATCTTGAAGTGGGTGACTTTGTTCACACCCTGGGTGATGCGCATCTTTACCTGAATCACCTTG
AACAGGCGAACCTGCAACTGACCCGTGAATTCCGTCCACTGCCTCAGTTGAAACTGAACCCGGCAAAGAAGGATCTTTTC
GACTTCACTTACGAAGACATCGAAATCATCGGTTACGATCCGCACCCGGCCATCAAGGCTGAGGTGGCAGTATGA

Protein sequence :
MKQYHDLIKTVLEHGVKKEDRTGTGTISMFGYQMRYNLQEGFPLLTTKKLHTRSIFHELLWFLKGETNIKYLHDNKVTIW
DEWADENGNLGPVYGKQWRSWETADGRTIDQITNVVEQIKKNPNSRRMLVVAFNPGDVDKMALPPCHAFFQFYVANGKLS
CQLYQRSADIFLGVPFNIASYALLTHMIAQVCDLEVGDFVHTLGDAHLYLNHLEQANLQLTREFRPLPQLKLNPAKKDLF
DFTYEDIEIIGYDPHPAIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-83 63