Gene Information

Name : guaA (Bd2080)
Accession : NP_968932.1
Strain : Bdellovibrio bacteriovorus HD100
Genome accession: NC_005363
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1989829 - 1991349 bp
Length : 1521 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCGTGGTTTTGTCATTCTTGATTTTGGTTCCCAGTTCACACAATTGATTGCCCGTCGTCTGCGCGAGATGGGTTTTTA
TTCAGAAATTCATTCCTTCGAATATCCCACGGAAGAAATCCGTAAGAAAAATCCTTACGGCATCATCTTAAGCGGCGGTC
CGAATTCAGTTTATGAAGCCGGTTCACCGCAAAGAAATGTGGCTGAACTTCGTAACATAAGTCCTGTGATGGGCGTTTGT
TATGGAATGCAGCTTTTGACTCACCAGTTAGGCGGCAAGGTGACTCGCGCTGAACACCGTGAGTATGGTCTGAATTATGT
AACATGGTCCAGTCCGGTCCAGGGTGTTCCTGAAAGACAAAAAGTTTGGATGAGTCACGGCGACGTGGTTGAAAAAGCCC
CCGAGGGTTTTAAAATCATCGCAAATTCCGACGGCCATCATCCCGCAGCCATGCAGGGTCCCGGCGTTTTGGCGGTGCAG
TTCCATCCCGAGGTGGCGCACACCGATCACGGAATGGATCTGTTGAAATATTTCGCGCAAGGCATGTGTAAAGCTCCGGC
GGACTGGGATGCTCCTCACATCAAGGATATTTTGATCAAGGAAGCGCAAGACAAAGTCGGACCTACGGATCATGTTCTGG
TGGGTTTAAGTGGCGGCGTTGATTCCACGGTGGTGGCGACTCTGCTGACCAAGGCTTTGGGTGCTGAGCGTGTTCACTGC
GTGTTTGTTGATAACGGTCTTTTGCGTAAAAACGAGTACGAAGCAGTGCTTGAGTCTTATCATCGCATTGGGCTGAATGT
GCGCGGTGTGGATGCTTCTGAAGAGTTTCTTTCAGCCCTTCAAGGAAAGTCTGATCCTGAAGACAAGCGTAAAACCATCG
GACGTGTGTTTATTGAAGTCTTTGATAAAAGCTATGATCACAAACTTCCGATCAAATGGCTGGCGCAAGGAACACTTTAT
CCGGATGTGATTGAAAGTGTGTCGTCAGTGGGCGGCAGTGTGACCATCAAGTCGCACCACAATGTGGGTGGTCTGCCGGA
AAAAATGAAATTGGGTCTGGTGGAGCCAGTTCGCGAATTGTTCAAAGATGAAGTGCGCGCTCTGGGGGCACAGCTTGGAC
TTCCAAAAGAAATGCTGTGGCGTCATCCGTTCCCGGGGCCGGGCTTGGCAATTCGTGTGTTGGGTGAAGTGACGAAAGAA
AAACTGCAAATTCTTAAAGAAGCAGATGATGTTTATATTTCAGAACTTCGCCGCCGCGGCCTTTACGAAAAAATCTGGCA
GGCGTTCTGTGTTTTGCTTCCGGTAAAAACCGTGGGCGTGCAGGGGGACTCCAGAACTTACGATCACGTTCTGGCCTTGC
GTGCAGTCACCTCCAGTGACGGCATGACCGCAGACTGGTATCCTTTCGAATTCCAGTTCCTGCGTGAGGTCTCCAATCTG
ATCACTAACAAAGTCAAAGGCGTCAACCGCGTCGTCTACGACGTCACCAGCAAACCCCCCGGCACCATCGAGTGGGAATA
A

Protein sequence :
MRGFVILDFGSQFTQLIARRLREMGFYSEIHSFEYPTEEIRKKNPYGIILSGGPNSVYEAGSPQRNVAELRNISPVMGVC
YGMQLLTHQLGGKVTRAEHREYGLNYVTWSSPVQGVPERQKVWMSHGDVVEKAPEGFKIIANSDGHHPAAMQGPGVLAVQ
FHPEVAHTDHGMDLLKYFAQGMCKAPADWDAPHIKDILIKEAQDKVGPTDHVLVGLSGGVDSTVVATLLTKALGAERVHC
VFVDNGLLRKNEYEAVLESYHRIGLNVRGVDASEEFLSALQGKSDPEDKRKTIGRVFIEVFDKSYDHKLPIKWLAQGTLY
PDVIESVSSVGGSVTIKSHHNVGGLPEKMKLGLVEPVRELFKDEVRALGAQLGLPKEMLWRHPFPGPGLAIRVLGEVTKE
KLQILKEADDVYISELRRRGLYEKIWQAFCVLLPVKTVGVQGDSRTYDHVLALRAVTSSDGMTADWYPFEFQFLREVSNL
ITNKVKGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-116 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-116 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-116 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-111 49