Gene Information

Name : smpB (LJ0878)
Accession : NP_964733.1
Strain : Lactobacillus johnsonii NCC 533
Genome accession: NC_005362
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 784464 - 784919 bp
Length : 456 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAAACAAAAAGCAGATAATTTGATTGCTCAAAATAAAAAAGCAAGTCATGATTATTTTATTAAAGAAACTCTTGAAGC
CGGAATTGCGTTAACTGGGACGGAGATTAAATCAATTCGTGCACGTAGAATTAATTTACGGGACGGATATGTTCAAATTA
TTAATGGATCTGCTTTTTTAGAAAATGTTCATATTAGTGAATATAAAGAAGGTAATCGCTATAATCATGATCCTTTACGA
TCACGGCGCTTGTTGCTTCATAAGAGAGAAATTGCTCGCCTAGCTGGAATTCAAGCTCAACAGGGAATGGCTATTATTCC
TTTAAAAGTCTATTTAAAACATGGATTTGCTAAAGTTTTAATTGGTGTGGGACAAGGTAAGAAGCAATATGATAAACGTC
AAACTATTAAAAAGCGTGATCAAGACCGTGAAATTCATCGTAAGTATGGGATTTAG

Protein sequence :
MKQKADNLIAQNKKASHDYFIKETLEAGIALTGTEIKSIRARRINLRDGYVQIINGSAFLENVHISEYKEGNRYNHDPLR
SRRLLLHKREIARLAGIQAQQGMAIIPLKVYLKHGFAKVLIGVGQGKKQYDKRQTIKKRDQDREIHRKYGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-37 59
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-26 44