Gene Information

Name : leuS (LJ0680)
Accession : NP_964532.1
Strain : Lactobacillus johnsonii NCC 533
Genome accession: NC_005362
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 567734 - 570148 bp
Length : 2415 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGTATAATCACAAAACTGTAGAAAAAAAGTGGCAAAAATACTGGGCTGAGCATGATACTTTTAAGACAGGCACTGATCC
TAAGAAAAAGAATTATTATGCTTTAGATATGTTCCCATTTCCATCTGGTAAAGGTCTTCATGTAGGACACCCAGAAGGAT
ATACTGCAACTGATATTGTTTCAAGAATGAAGAGAGCCCAAGGCTATAATGTTCTTCATCCAATGGGCTGGGATGCATTT
GGTCTTCCAACTGAACAATATGCCTTAAAGACTGGTGAAGACCCAGAAAAAGTTACTAAAGAAAATATTGCTAATTTTAA
AAAGCAACTGAATAAGCTTGGTTTTTCGTATGATTGGGACCGCGAAGTTACTACTTCTGATCCAAATTACTATAAGTGGA
CTCAATGGGTTTTTGAACAAATGTATAAGAAGGGCTTGGCATATGAAGCTGAAGTTCCTGTTAACTGGTCTCCAGATCTA
GGCACAGTTGTTGCAAATGAAGAGATTATTGATGGTAAAACTGAACGTGGTGGTTATCCAGTTTACCGTCGTAATATGCG
TCAATGGATGCTTAAGATGACAGCTTATGCTGATCGCTTGCTCGAAGATTTAGATGATTTAGATTGGCCAGAGCCAGTTA
AAGAAATGCAAAGAAACTGGATTGGTCGCTCAGAAGGAGCTCAAGTTACTTTTAAGGTTAAAGATAGTGATAAAACATTT
GATGTGTTTACTACACGTCCTGATACCTTATTTGGTGTTAGTTACACTGTCTTAGCTCCTGAAAGTAAGTTAGTTCAAGA
AATTACAACTCCTGAACAAAAAGAAGCTGTGGATGCTTACATTAAGAAAATTGAATCAAAGTCTGATCTAGAAAGAACTG
ATCTAAATAAAGACAAGACCGGTGTCTTTACTGGTGCCTATGCAGTTAATCCAGTAAATGGAAAAGAAGTTCCAATTTGG
ATTTCTGATTATGTTTTAGCAAGTTATGGTACTGGTGCAGTAATGGCGGTACCAGCTCATGATGATCGTGACTATGCTTT
TGCAACTAAATTTGGCTTGCCGATCAATCGAGTTATTGAAGGTGGAAATTTAGAAAAAGAAGCCTTTGGTGGAGATGGTA
AACACATCAATTCTGAATTCTTAGATGGTTTAAACAATGAAGAAGCTAAGAAGAGAATGATTGAGTGGCTTGAAGATCAC
AATGTAGGTGAAAAGAAGGTTAATTATAAACTTCGTGACTGGGACTTTAGTCGTCAACGTTACTGGGGTGAACCAATTCC
TGTAATTCACTGGGAAGATGGTACTACTTCACTAGTTCCAGAAGATGAATTACCATTACGTTTGCCACATGCAACTGACA
TTAAGCCATCAGGTACTCCAGAAAGTCCACTTGCCAATTTGACTGATTGGGTAAACGTTGTTGATGAAAACGGTCGAAAA
GGTAAGCGTGAAACTAATACTATGCCTAACTGGGCAGGTTCAAGTTGGTACTACTTACGCTATATTGATCCACATAACGA
TAAAGAATTGGCTGACTATGATTTACTTAAGAAGTGGCTCCCTGTAGATCTTTACATTGGTGGGGCAGAACACGCTGTTC
GTCACTTACTCTATGCTAGATTTTGGCACAAGGTTCTTTATGACTTGGGTGTTGTACCAACTAAAGAGCCATTCCAAAAG
CTTTATAATCAAGGTTTGATTTTAAAGAATCATGAAAAGATGTCTAAGTCTAAAGGAAATGTTGTTAACCCTGATGAAGT
AATCGATGAATATGGTGCAGATTCACTTAGAATGTACGAAATGTTCATGGGTCCATTAGATGCTTCAATTGATTGGGATG
ATAATGGTCCTGCATCTACTAAGAAATTCTTAGATCGTGTATGGCGCTTATTTGTTAACGATCTTGACCTAAAGGCAATT
CCTCAAGAAAAGATTGTTGACGAAAATGATGGTGAACTTGATAAGGTATATGCCGAGACTGTCAAAAAGGTTACAGAAGA
CTTTGAAGCTTTACACTTTAATACTGCAATTAGTCAAATGATGGTCTTTATGAATGCAGCTCAAAAAGCTAAGACTATTC
CACGTGAATATGCAGAAGGATTTGTACAACTTCTTGCTCCTGTTGCACCTCACATGATGGAAGAAATCTGGTCAGTATTT
GGTCATGATGAATCTATTGCATATGCGAAATGGCCAGAATATGATCCTGCAAAATTAGTTGAATCAACAGTTGAAATTAT
GGTTCAAGTTAATGGTAAGCTTCGCGGCAAATTTAAGGCTGCTAAGGATAGTGATAAAGATACCTTAGAAAAAGAAGCTC
TTGCTCTTGATCATGTTCAAAAATTCTTAGAAGGAAAAGATGTCAAGAAAGTCATCGTTATTCCAAACAAAATTGTTAAT
ATTGTTGCTAAGTAA

Protein sequence :
MYNHKTVEKKWQKYWAEHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVSRMKRAQGYNVLHPMGWDAF
GLPTEQYALKTGEDPEKVTKENIANFKKQLNKLGFSYDWDREVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDL
GTVVANEEIIDGKTERGGYPVYRRNMRQWMLKMTAYADRLLEDLDDLDWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF
DVFTTRPDTLFGVSYTVLAPESKLVQEITTPEQKEAVDAYIKKIESKSDLERTDLNKDKTGVFTGAYAVNPVNGKEVPIW
ISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINRVIEGGNLEKEAFGGDGKHINSEFLDGLNNEEAKKRMIEWLEDH
NVGEKKVNYKLRDWDFSRQRYWGEPIPVIHWEDGTTSLVPEDELPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK
GKRETNTMPNWAGSSWYYLRYIDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYARFWHKVLYDLGVVPTKEPFQK
LYNQGLILKNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDRVWRLFVNDLDLKAI
PQEKIVDENDGELDKVYAETVKKVTEDFEALHFNTAISQMMVFMNAAQKAKTIPREYAEGFVQLLAPVAPHMMEEIWSVF
GHDESIAYAKWPEYDPAKLVESTVEIMVQVNGKLRGKFKAAKDSDKDTLEKEALALDHVQKFLEGKDVKKVIVIPNKIVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65