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Name : azi; div (LJ0388) Accession : NP_964412.1 Strain : Lactobacillus johnsonii NCC 533 Genome accession: NC_005362 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 430140 - 432506 bp Length : 2367 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGCTAACAGATAGGTTAAGACTAAAAAAAGCCAGGAAATTATTAAATAAAATTAATAAATTAGGTCCTAAAATGCAGGC AATGAGTGATGAAAAACTGCAAGGACAAACTGCTATTTTTAAAAAGCAACTTAAAGAAGGTAAAAGTTTAGATGATATTT TACCAGAAGCTTATGCCACTGTAAGGGAAGCAGATAAAAGAATTTTGGGGATGTTCCCCTATGATGTACAGGTTTTAGGG GCAATTGTATTACATAATGGCTCCATTGCTGAAATGAAAACTGGGGAAGGTAAAACTTTAGTTGCGACAATGGCTCTTTA TCTAAATGCTTTAGAAGGTAAAGGCGCAATGTTAGTGACTCCAAATGGTTATCTTGCATCTCGTGATAAAAAAGAGTTAG CTCCAGTTTATGAGTGGCTAGGTTTAAGTGTTAGCTTAGCTTTTGCAGAAGAGAAAGATAGTAAAAAGAAAATAACTGCT AAAACTAAAAGAAAATGGTATAACTCCGATATTGTATATACTACTGCTTCTTCTTTAGCTTTTGATTATTTGTTTAATAA TCTTGCCAGCTCCAAAGAAAATCAATATTTACGCCCATTTAATTATGTTATTGTCGATGAAGTGGATGAGGTTTTATTAG ATGAAGCACAGACTCCATTCGTGGTCTCCTCTAGTCCTAATGTTCAATCAAATCTATATCATTTGGCAGATCAGTTTGTA AGACTATTAGATCCCGAGGTGGACTATGTATTTAAAAAGGATGATCAATTATTTTGGTTAACAGCCCACGGTATTGAAAA AGCTGAGCAATTTTTTAAACTAGATAGCTTATTTTCTAATGAGAGCAGGAGTGTTTATCGCCATATTATTTTAGCGATGG GTGCGCACTTAACTATGAGACGAGGACATGACTACTTAGTTGTAAAAGGCGAAGTGGTCTTGTTAGATGAAGATAGCGGT AGATTAAAACGTGGAGTTCAGGTAAGTACAGGAATTCACCAGGCTGTTGAAGCTAAAGAAAAGGTTGAGTTGACTAAAAT TCAGAAAACAGCAGCTTCAATAACATTTCCAGCTTTATTTGCATTGTTTAATAAAGTAAGTGGAATGAGTGGAACTGCTA AAGTTAATGAAGAAGAGTTTTTACAGACCTATAATTTAAAAGTGGTAACTATCCCTACAAGAGTGCCGGTAATTAGAAAA GATTATCGCCCACTTATTTTCTTAACTACAATAGATAAATTAATGACAGCTGTAGATGATGTAGTAGAAATGCATAAAAC TGGTCGGCCTGTGTTACTTGTTGCTGGTTCTGTAGAAAATTCAGAAATTATTTCAGAACTATTACTCAATATTGGTATTC CTCATAATGTTTTAAATGCCTATAATGCAGCCTATGAAGCGCAAATTATTAAAAATGCAGGTCAAAAAAATGCTGTAACT ATTGCAACAAATATGGCTGGTAGAGGAACTGATATTAAGCTAGGACCCGGAGTTAAGGAACTAGGTGGCTTAGCAGTAAT TGGAACTGAAATGTTACCTAAAAGGGTGGAATTGCAGCTAGCGGGGCGTGCTGGCAGACAAGGAGATCCAGGTAGCAGCC AATTTCTGATTTCCTTAGAGGATTCATTTATTTCTTCTAATAATACTCCTCGTCAGAAGAAGTATTACCGCAAATTAATG AAGAAGAAGTCAAAGGGAAAGGATATTACTCTTCTCTCAGGTCCGCGAATTCGATTTAGTTTGCTCATGCTGAGAACCCG TAAAGAAGATCTTAATGAGTTGATGAGAAGTCAAACTAATAAGATGGAAATAATTTTATCGCTTCAACGGAAGAATTTTT ATACTAGAAGAGACAAAATTATGAAAACTGATGATTTACAGGAAGATGTAGATCGGATCATCGATAATGCACTGAATCTT TATTTAGAAAAACAGGATTTATCAAATAAGAGTGATTTAAAGTACTTTATTAACCAGCATGTTACTTATCAACAGGTTAA TGTACCAGATAATTTGAAAACTAAAAAAGCAATTAAAGACTTTTTGAAAGAATTAGCTTACAAGATTCTTGATGAGAAGA AGCATGTATTAATTAACAAAAAACAAGCAAATGATTTTTACCAACAAGTGATTATTTCATCAATGGATGGAAATTGGATT GATCAAGTAGATAGAATTGAAAAAATAAAGATTAATGCACAGCAATGGGGAAGAAGTGGAAGACCGCAAGATCTTCTCCA CCAAGAAAAGGCTTTTGAAGCGTATAAAGATTTCTTAGATAAAATTACCTTGTCTACCTTTGATAATCTTTTATTAAGCA AGATTTTTACGAATGAAAAAGGACAATTAGTTGTAGTATTTAATTAG Protein sequence : MLTDRLRLKKARKLLNKINKLGPKMQAMSDEKLQGQTAIFKKQLKEGKSLDDILPEAYATVREADKRILGMFPYDVQVLG AIVLHNGSIAEMKTGEGKTLVATMALYLNALEGKGAMLVTPNGYLASRDKKELAPVYEWLGLSVSLAFAEEKDSKKKITA KTKRKWYNSDIVYTTASSLAFDYLFNNLASSKENQYLRPFNYVIVDEVDEVLLDEAQTPFVVSSSPNVQSNLYHLADQFV RLLDPEVDYVFKKDDQLFWLTAHGIEKAEQFFKLDSLFSNESRSVYRHIILAMGAHLTMRRGHDYLVVKGEVVLLDEDSG RLKRGVQVSTGIHQAVEAKEKVELTKIQKTAASITFPALFALFNKVSGMSGTAKVNEEEFLQTYNLKVVTIPTRVPVIRK DYRPLIFLTTIDKLMTAVDDVVEMHKTGRPVLLVAGSVENSEIISELLLNIGIPHNVLNAYNAAYEAQIIKNAGQKNAVT IATNMAGRGTDIKLGPGVKELGGLAVIGTEMLPKRVELQLAGRAGRQGDPGSSQFLISLEDSFISSNNTPRQKKYYRKLM KKKSKGKDITLLSGPRIRFSLLMLRTRKEDLNELMRSQTNKMEIILSLQRKNFYTRRDKIMKTDDLQEDVDRIIDNALNL YLEKQDLSNKSDLKYFINQHVTYQQVNVPDNLKTKKAIKDFLKELAYKILDEKKHVLINKKQANDFYQQVIISSMDGNWI DQVDRIEKIKINAQQWGRSGRPQDLLHQEKAFEAYKDFLDKITLSTFDNLLLSKIFTNEKGQLVVVFN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 6e-140 | 45 |
