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Name : guaA (LJ0229) Accession : NP_964244.1 Strain : Lactobacillus johnsonii NCC 533 Genome accession: NC_005362 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 264154 - 265707 bp Length : 1554 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : GTGGCTAAGACTAATCTAAATGATTTTGACAAGATTATTGTGCTTGATTTTGGTAGTCAATATAACCAATTGATTACTCG TCGAATTCGTGACTTTGGTATCTATTCAGAACTTTTACCACATGACTTAAGTATTGAAAAGATCAAAGAAATGGCCCCTA AGGGAATTATCTTTTCCGGTGGTCCAAACAGTGTTTACGATAAGGGTGCTTTAAAAGTTGATCCTGAAATTTTCAAGCTT GGTATTCCAATTTTGGGGATTTGTTATGGGATGCAACTCATGAGTTACGATTTAGGCGGTAAGGTTGAAAAGGCTGATAA TTCCGAATATGGTCGTGCTGATATTGAGGTAATTGATCCTAATGCAGTTTTATTTGAGGGCTTGCCAAGAGAACAATACG TTTGGATGAGTCATGGTGACTTAGTAACTAAGGCTCCAGAAGGCTTTACTATAACTGCTAAGAGTAAGAATTGTCCAATT TCTGCAATTGCTAACGACGAGAAGAAGTTCTATGGAATTCAATTCCATGCCGAAGTTCGTAATTCCGAATATGGTTTAGA TATTTTGAAGAACTTTGCATTTAAGGTTTGTGGTGCCAAAGCTAACTGGACCATGGATGACTTTATCGAGATGCAAGTTG ATGAAATTCGTAAAAAAGTTGGCGATAAGAAGGTTATCTTAGGCCTTTCTGGTGGGGTCGATTCTAGTGTTACTGCAACT CTTCTTCACAAGGCAATTGGCGATCAGTTAACTGCGATTTTTGTTGATCACGGGATGCTTCGTAAAGATGAAGGCGATCA AGTAATGCAAGCTTTGAATAAGGATCTTGGGGTTAATATTATTCGCGTGAATGCCCAAGAGCGTTTCTTGAATAAGCTCA AGGGAGTAACTGATCCTGAACAAAAACGTAAGATCATCGGTAAAGAATTCATTGAAGTCTTCAACGAAGAAGCTAAAAAG TTAAAGGATGTTGACTTCTTAGCCCAAGGTACTTTATATACTGATGTTATTGAGTCCGGAACTAATACTGCTCAAACTAT TAAGTCACACCACAATGTTGGTGGCCTTCCTGAGGACATGCACTTTGAATTAATTGAACCACTTCGTAAACTTTTCAAGG ATGAAGTTCGTGAACTTGGTGAAAAGCTCGGTATTCCTCATGATTTGGTATGGCGTCAACCATTCCCAGGTCCAGGTCTT GGTATTCGTGTTATTGGTGAAGTTACTGAAGACAAGCTTAAGATTGTGCGTGAATCAGATGCGATTTTACGTGAAGAAAT CAAGAATGCTGGTCTTCAAGAAGATATTTGGCAATACTTCACGGTTCTTCCAGGTATTCGCTCAGTTGGGGTTATGGGAG ATGGGCGTACTTACGACTACACTATCGGTATTCGTGCCGTAACTTCAATTGATGGTATGACTGCTGATTTTGCCCAAATT CCATGGGATGTTTTGAGCAAGATTTCTACTAGAATTGTAGATGAATGTGACCACATTAACCGCGTAGTTTACGATATTAC CAGTAAGCCACCTTCCACTATTGAATGGGAATAA Protein sequence : MAKTNLNDFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIEKIKEMAPKGIIFSGGPNSVYDKGALKVDPEIFKL GIPILGICYGMQLMSYDLGGKVEKADNSEYGRADIEVIDPNAVLFEGLPREQYVWMSHGDLVTKAPEGFTITAKSKNCPI SAIANDEKKFYGIQFHAEVRNSEYGLDILKNFAFKVCGAKANWTMDDFIEMQVDEIRKKVGDKKVILGLSGGVDSSVTAT LLHKAIGDQLTAIFVDHGMLRKDEGDQVMQALNKDLGVNIIRVNAQERFLNKLKGVTDPEQKRKIIGKEFIEVFNEEAKK LKDVDFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPEDMHFELIEPLRKLFKDEVRELGEKLGIPHDLVWRQPFPGPGL GIRVIGEVTEDKLKIVRESDAILREEIKNAGLQEDIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDGMTADFAQI PWDVLSKISTRIVDECDHINRVVYDITSKPPSTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 7e-179 | 70 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 5e-179 | 70 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 5e-179 | 70 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 4e-132 | 51 |
