Gene Information

Name : LJ0676 (LJ0676)
Accession : NP_965579.1
Strain : Lactobacillus johnsonii NCC 533
Genome accession: NC_005362
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1686282 - 1687592 bp
Length : 1311 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATTAAAGTAATTCGAGAGAATTTAGACTGGTCAAAGAAAAAATTAGCTACACGAGGAATTAAACCAGAGGA
ATTAGATAAATTAGTAGCTATTGATAAAGAAAGACGTGAAGCTTTAACTAAGAGTGAACAATTAAAGCAAAAGCGTAATG
AAGTATCTGATCAAATTGCTCAAGCTAAACGCAATAAAGAAGATGCAAGTGATGCTATTAAAGCAATGCGTGAAGTAGGT
AAAGAAATTAAGGATTTAGATAAAGAAGTAGAAGATTTAACTCAAAAACAAAACTATATCTTACTTCGTTTACCTAACTT
CCCAGCAGACTCAGATCCTATTGGACCTGATGAAAGTTACAATGAAGAAGTGCGTAAGTGGCATGAGCCTACTAAACTTG
ATTTTGAACCAAAACCTCACTGGGAAATTGGAACAGAATTGAATATTTTAGACTGGGATACTGCTGCTAAAGTTTCAGGT
GCCCGCTTTGTTTATTACAAAGGTGCAGGTGCATTGCTTGAACGTGCAGTTTCAAACTTCTTCTTAGATGAAAATACTAA
AGATGGATATACTGAAGTAATTCCACCATACTTAGTTAACGATGCTTCTATGCAAGGAACTGGTCAATTCCCTAAGTTTA
CTGAAGATGTTTATACAATTGTAGATAATGATGATCCTGATAAGCCACGTGATTTAACTTTAATTCCAACTGCTGAAGTA
CCATTAGTTAATTACTTCCGTGGCAAGATTTTAGATGGAGAGCAATTACCAATTAATGTAACTGCATTCTCTCCAGCATT
TAGAAGTGAAGCGGGATCAGCTGGACGTGACACTCGTGGATTAATCAGAATGCACGAATTTAGAAAAGTTGAAATGGTAA
AAATTGTTGACGAAGAAAGTTCATGGGATGAATTGGAAAAATTAACCCATAATGCTGAACATTTACTTCAAAAACTTGGT
TTACCATATCATGTTGTTGCTCTTTCAACTGGGGATGCAAGTTTTACTAGTGCAAAAACTTATGATCTAGAAGTTTGGAT
GCCAGCACAAGATAAGTATCGTGAAATTTCAAGTTGTTCAAACTGTACTGACTTCCAAGCACGTCGTAGTTTGATTCGTT
ACAGAGACGAAAATGGTAAACTTCATTTAGCACATACTTTAAATGGTTCTGGTCTAGCTGTAGGTAGAACAGTAGCTGCT
ATTTTGGAAAATTACCAAAACGAAGACGGAACTGTAAATGTTCCAGAAGCTTTACAACCATATATGCATGGAATGAAAGT
TATTACTAAAGAGCCAAAATTTGGTGAATAA

Protein sequence :
MLDIKVIRENLDWSKKKLATRGIKPEELDKLVAIDKERREALTKSEQLKQKRNEVSDQIAQAKRNKEDASDAIKAMREVG
KEIKDLDKEVEDLTQKQNYILLRLPNFPADSDPIGPDESYNEEVRKWHEPTKLDFEPKPHWEIGTELNILDWDTAAKVSG
ARFVYYKGAGALLERAVSNFFLDENTKDGYTEVIPPYLVNDASMQGTGQFPKFTEDVYTIVDNDDPDKPRDLTLIPTAEV
PLVNYFRGKILDGEQLPINVTAFSPAFRSEAGSAGRDTRGLIRMHEFRKVEMVKIVDEESSWDELEKLTHNAEHLLQKLG
LPYHVVALSTGDASFTSAKTYDLEVWMPAQDKYREISSCSNCTDFQARRSLIRYRDENGKLHLAHTLNGSGLAVGRTVAA
ILENYQNEDGTVNVPEALQPYMHGMKVITKEPKFGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-126 63