Gene Information

Name : thyA (LJ1471)
Accession : NP_965273.1
Strain : Lactobacillus johnsonii NCC 533
Genome accession: NC_005362
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1335834 - 1336790 bp
Length : 957 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGGCAACTTTAGAGCAACCATATTTAGATTTACTAAGTAAAATAATGAGTGAAGGGCATGACAAGGAAGATAGGACTGG
TACAGGTACTAGAAGCTTGTTTGGAGCCCAAATGAGATTTGATTTAAATGATGGCTTTCCTATTTTAACTACTAAAAAAA
TACCTTTTGGACTTATTAAGAGCGAATTGTTATGGTTTTTACGAGGAGACACTAATATCCGTTTTTTGCTAGAACATAAT
AATCATATTTGGGATGAATGGGCCTTTAAAAATTGGGTAGAGAGCAATGAATATCAGGGGCCAGATATGACTAATTTTGG
TCTAAGAAGTCAACAAGACCCAGAATTTAAAAGAATATATCAAGAAGAAATGAAAAAATTTGATCAAAAAGTCTTGGAAG
ATCAAACTTTCGCAGAAAAATATGGAAATTTAGGAGACGTTTATGGTGCTCAATGGAGACATTGGCAGAAGCGTGAAGGT
GGCTTTATTGATCAAATTCAAAATGTAATTGATCAAATTAAGAAAACACCTTATTCTCGTCGCTTAATTGTTAGCGCATG
GAATCCCGAAGATGTACCAACGTCTGCTTTACCGCCATGTCATGTCTTGTTTCAGTTTTATGTTAATGACGGGTGTTTAA
GTTTACAACTGTATCAAAGATCAGGCGACATGTTTTTAGGTGTACCGTTTAATATTGCGAGTTATGCTTTACTAGTAAAT
TTAGTCGCGCGTGAAACGGGACTAAAGCCGGGTGAATTTATTCATACCTTAGGGGATGCTCATATTTATAAAAATCACTT
TAACCAAGTTAAAGAATTATTGAATCGATCTGCATATGACGCTCCTATGCTTTGGCTAAATCCGGATAAAAAATTAGTAC
AGGATTTTGAAATGAAAGATATCAAGTTAATTAATTACCGGCATCATGGCACTATTAAGGCGCCGGTAGCCGTTTAA

Protein sequence :
MATLEQPYLDLLSKIMSEGHDKEDRTGTGTRSLFGAQMRFDLNDGFPILTTKKIPFGLIKSELLWFLRGDTNIRFLLEHN
NHIWDEWAFKNWVESNEYQGPDMTNFGLRSQQDPEFKRIYQEEMKKFDQKVLEDQTFAEKYGNLGDVYGAQWRHWQKREG
GFIDQIQNVIDQIKKTPYSRRLIVSAWNPEDVPTSALPPCHVLFQFYVNDGCLSLQLYQRSGDMFLGVPFNIASYALLVN
LVARETGLKPGEFIHTLGDAHIYKNHFNQVKELLNRSAYDAPMLWLNPDKKLVQDFEMKDIKLINYRHHGTIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-93 59