|
Name : ureC (RPA3660) Accession : NP_948998.1 Strain : Rhodopseudomonas palustris CGA009 Genome accession: NC_005296 Putative virulence/resistance : Virulence Product : urease subunit alpha Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0804 EC number : - Position : 4133317 - 4135029 bp Length : 1713 bp Strand : - Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alp DNA sequence : GTGAGCACCAGGATTTCACGTTCCGTCTATGCCGACATGTTCGGTCCGACCACCGGCGACCGCGTCCGGCTCGCCGACAC CGATCTGATCATCGAGGTCGAGAAGGATCTCACCACCTATGGCGAGGAGGTGAAGTTCGGCGGCGGCAAGGTGATCCGCG ACGGCATGGGCCAGTCGCAGGTGACCAACAAGGACGGCGCCGCCGACACGGTGATTACCAACGCGCTGATCGTCGACCAC TGGGGCATCGTTAAGGCCGACGTCGCCATCACCGCCGGCGTGATCACCGCGATCGGCAAGGCCGGCAATCCGGACGTTCA GCCGAATGTCGATATCATCATCGGTCCCGGCACCGACGTCATCGCCGGCGAAGGCAAGATACTCACCGCCGGCGGGTTCG ACAGCCACATCCATTTCATCTGCCCGCAGCAGATCGAGCACGCGCTGATGAGCGGCGTCACGACCATGCTAGGCGGCGGC ACCGGCCCATCGCACGGCACGTTTGCGACGACGTGCACGCCGGGCCCGTGGCACATCGGCCGGATGATTCAATCGTTCGA CGCCTTCCCGGTCAATCTCGGCATCTCCGGCAAGGGTAACGCGGCGCTGCCGGGTCCGCTGAAGGAAATGATCGAAGGCG GGGCCTGCGCGCTGAAGCTGCACGAGGACTGGGGCACGACGCCGGCGGCGATCGACAACTGTCTCACCGTCGCCGACGCC TACGACATCCAGGTGATGATCCACACCGACACACTCAACGAGTCGGGTTTCGTCGAAGACACTGTGAAGGCGTTCAAGGG GCGCACCATCCACGCCTTCCACACCGAAGGCGCCGGCGGCGGCCACGCGCCGGACATCATCAAGGTCGCGAGCCTGGAAA ACGTGCTGCCGTCGTCGACTAATCCGACCCGGCCGTTTACCCGCAACACCATCGACGAGCATCTCGACATGCTGATGGTG TGCCACCATCTCGACCCGTCGATCGCGGAAGATCTGGCCTTCGCCGAGAGCCGTATCCGGAAAGAGACGATCGCGGCCGA GGACATCCTCCACGACCTCGGTGCGCTGTCGATGATGTCGTCGGATAGTCAGGCGATGGGCCGGCTCGGCGAAGTGATCA TCCGCACCTGGCAGACCGCCGACAAGATGAAAAAGCAGCGCGGCGCGCTGCCGCAGGACTCGGCGCGCAACGATAATTTC CGGGTCAAGCGCTACATCGCCAAGTACACCATCAATCCGGCGATCGCGCACGGCGTGTCGAAACTGATCGGCTCGGTTGA GACCGGCAAGATGGCCGATCTGGTGCTGTGGTCGCCGGCGTTCTTCGGCGTCAAGCCGGACTGCATCATCAAGGGTGGCA GTATCGTCGCGGCACCGATGGGCGACCCGAACGCCTCGATCCCGACGCCGCAGCCGGTGCACTATCAGCCGATGTTCGGC GCCTACGGCAAGGCGCTGACCGCGTCGTCGGTGGTGTTCACCTCGCAGGCGGCAGCCGCCGGCAATCTCGCCCGCGACCT CGGCATCGCCAAGAAGCTGGTTCCGGTCAGCAACGTCCGCGGCGGCATTTCCAAGAAGAGCATGATCCACAACGACGCCA CGCCGAAGCTCGAAGTCGATCCCGAGACCTACGAAGTCCGCGCCGACGGCGAACTGCTCACCTGCGCCCCGGCCGAAGTG CTGCCGCTGGCGCAGCGTTACTTCATGTTCTGA Protein sequence : MSTRISRSVYADMFGPTTGDRVRLADTDLIIEVEKDLTTYGEEVKFGGGKVIRDGMGQSQVTNKDGAADTVITNALIVDH WGIVKADVAITAGVITAIGKAGNPDVQPNVDIIIGPGTDVIAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTTMLGGG TGPSHGTFATTCTPGPWHIGRMIQSFDAFPVNLGISGKGNAALPGPLKEMIEGGACALKLHEDWGTTPAAIDNCLTVADA YDIQVMIHTDTLNESGFVEDTVKAFKGRTIHAFHTEGAGGGHAPDIIKVASLENVLPSSTNPTRPFTRNTIDEHLDMLMV CHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDSARNDNF RVKRYIAKYTINPAIAHGVSKLIGSVETGKMADLVLWSPAFFGVKPDCIIKGGSIVAAPMGDPNASIPTPQPVHYQPMFG AYGKALTASSVVFTSQAAAAGNLARDLGIAKKLVPVSNVRGGISKKSMIHNDATPKLEVDPETYEVRADGELLTCAPAEV LPLAQRYFMF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ureC | NP_286680.1 | urease subunit alpha | Virulence | TAI | Protein | 0.0 | 67 |
| ureC | NP_287088.1 | urease subunit alpha | Not tested | TAI | Protein | 0.0 | 67 |
| ureC | YP_005682174.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 6e-162 | 62 |
| ureC | YP_003784325.1 | urease subunit alpha | Not tested | PiCp 7 | Protein | 6e-162 | 62 |
| ureC | YP_005686358.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 6e-162 | 62 |
| ureC | YP_005684266.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 8e-162 | 62 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ureC | NP_948998.1 | urease subunit alpha | VFG0270 | Protein | 9e-158 | 61 |
