Gene Information

Name : thyA (RPA3493)
Accession : NP_948831.1
Strain : Rhodopseudomonas palustris CGA009
Genome accession: NC_005296
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 3942978 - 3943772 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGATCCAATATCAGGACCTGCTCGAACGCATCTTGAGCGACGGGGCCGAAAAGCACGACCGCACTGGCACCGGCACGCT
GTCGGTATTCGGGCATCAGATGCGGTTCGACCTCGCCGCCGGCTTTCCGATGCTGACCACCAAGCGGCTGCCGCTGAAGG
CGATTGTGCACGAGCTGCTATGGTTCCTGCAGGGCGATACCAACATCAAATACCTGCACGATCACGGCGTCACGATCTGG
GACGAGTGGGCGGACGCCAACGGCGATCTCGGCCCAGTGTACGGCGCACAGTGGCGCTCGTGGCCGACCGCGGATGGTGG
CTCGATCGATCAGATCGCCAATGTGGTCGAGATGATCAAGCGTAATCCGGATTCGCGGCGGCTGATGGTGACGGCGTGGA
ATCCGGCCGACGTCGAGAAGATGGCGCTGCCGCCGTGCCACTGCCTGTTCCAGTTCTATGTCGCGAACGGCAAGCTGTCG
TGTCAGCTGTATCAGCGCTCGGCCGACGTGTTTCTCGGCGTGCCGTTCAACATCGCATCGTACGCGCTGCTGACGCTGAT
GGTGGCGCAAGTCACTGGTCTAAAGCCCGGCGAGTTCGTCCACACTCTTGGCGACGCGCACCTGTATTCCAATCACCTGG
AGCAGGCGCGGCTGCAACTGACCCGTGCCCCGCGCGCGCTGCCGGTGATGACGATCAATCCGGCGGTGAAGGACATCTTC
GGCTTCCGCTACGAGGATTTCACCCTGACCGGCTACGATCCGCACCCTCACATCAAGGCCGAGGTGGCGGTGTGA

Protein sequence :
MIQYQDLLERILSDGAEKHDRTGTGTLSVFGHQMRFDLAAGFPMLTTKRLPLKAIVHELLWFLQGDTNIKYLHDHGVTIW
DEWADANGDLGPVYGAQWRSWPTADGGSIDQIANVVEMIKRNPDSRRLMVTAWNPADVEKMALPPCHCLFQFYVANGKLS
CQLYQRSADVFLGVPFNIASYALLTLMVAQVTGLKPGEFVHTLGDAHLYSNHLEQARLQLTRAPRALPVMTINPAVKDIF
GFRYEDFTLTGYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-84 64