Gene Information

Name : guaA (RPA2203)
Accession : NP_947548.1
Strain : Rhodopseudomonas palustris CGA009
Genome accession: NC_005296
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2480182 - 2481804 bp
Length : 1623 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAGCCCCCAGCACATCCTCCGCTTCGTCCGTCGTCCCCTCTGGCGCCGATACCTCGCCGCACGTCGCTGCGATCCA
CGAGAAGATCCTGATCGTCGACTTCGGCTCGCAGGTCACCCAGCTGATCGCCCGCCGCGTCCGCGAGGAGGGCGTGTATT
CCGAAATCGTGCCGTTCCAGAAGGCGGAGGCCGCCTTCGCCGAGATGAAGCCGAAAGCCGTGATCCTGTCCGGCGGTCCG
GCCTCGGTGCTGGACGACAACGCGCCCAGCGCCCCGATGACGATCCTGGAAGCCGGCGTACCGGTGCTCGGCATCTGCTA
CGGCGAACAGACGCTGGCCAAGCAGCTCGGCGGCACCGTCGAGGGCGGCCACCACCGCGAGTTCGGCCGCGCCCAGATCG
AGATCACCGATGATTGCGCGCTGTTCGACGGCATCTGGCAGAAGGGCGGCAAATACGACGTCTGGATGAGCCATGGCGAT
CGCGTCACCAAGCTGCCGGCAGGTTTCCGCGCGGTGGCGCAGGCGCCGGGATCGCCGATCTCGGTGATCGCCGACGACAC
CCGCAAATTCTACGCGATGCAGTTCCACCCCGAAGTGGTGCACACGCCCGACGGCGCCAAGCTGCTAAGCAATTTCGTCC
GCAAGGTCGCAGGCCTCACCGGCGACTGGACGATGCGCGCCTTCCGCGAGGAAGCGATCGAGAAAATCCGCGCCCAGGTC
GGCACCGGCAAGGTGATCTGCGGCCTGTCCGGCGGCGTCGATTCCGCGGTGGCGGCGGTGCTGATCCATGAAGCGATCGG
CGATCAGCTCACTTGCGTGTTCGTCGACCACGGCCTCTTGCGCAAGGACGAGGGCAAGAGCGTCGTCGACCTGTTCCGCC
ACCACTACAACATCCCGCTGGTGCACGTGGATGTGTCCGAGACCTTCCTCGGCGCGCTGAAGGGCGTCACCGATCCGGAG
CAGAAGCGCAAGACCATCGGCAAACTGTTCATCGACGTGTTCGAGGCCGAAGCCAGACGCGTCGGCGGCGCCGACTTCCT
GGCGCAGGGCACGCTGTATCCGGACGTGATCGAAAGCGTGTCGTTCACCGGCGGCCCGTCGGTGACGATCAAGTCGCATC
ACAACGTCGGCGGCTTGCCCGAACGTATGAACATGAAGCTGGTCGAGCCCTTGCGCGAATTGTTCAAGGACGAAGTCCGC
GCATTGGGGCGCGAGCTCGGGCTGCCCGACGTGTTCGTCGGCCGCCATCCGTTCCCGGGCCCCGGCCTCGCGATCCGCTG
CCCCGGCGAGATCACCGAGGAGAAGCTCGAAATCCTGCGCAACGCGGACGCGGTGTACATCGACCAGATCCGCAAGGCGG
GCCTGTACGATGTCATCTGGCAGGCGTTCGCCGTGCTGCTCCCGGTCCGCAGCGTCGGCGTGATGGGCGACGGCCGCACC
TACGACTACGTCGTCGGCCTCCGCGCCGTGACGTCCACCGACGGCATGACCGCCGACTTCTACCCGTTCGAGATGTCCTT
CCTCGGCGCCACCGCGACGCGGATCATCAACGAGGTCAAGGGCGTCAACCGCGTGGTGTACGACGTCACGTCGAAGCCGC
CGGGGACGATTGAGTGGGAATGA

Protein sequence :
MTAPSTSSASSVVPSGADTSPHVAAIHEKILIVDFGSQVTQLIARRVREEGVYSEIVPFQKAEAAFAEMKPKAVILSGGP
ASVLDDNAPSAPMTILEAGVPVLGICYGEQTLAKQLGGTVEGGHHREFGRAQIEITDDCALFDGIWQKGGKYDVWMSHGD
RVTKLPAGFRAVAQAPGSPISVIADDTRKFYAMQFHPEVVHTPDGAKLLSNFVRKVAGLTGDWTMRAFREEAIEKIRAQV
GTGKVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRKDEGKSVVDLFRHHYNIPLVHVDVSETFLGALKGVTDPE
QKRKTIGKLFIDVFEAEARRVGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVR
ALGRELGLPDVFVGRHPFPGPGLAIRCPGEITEEKLEILRNADAVYIDQIRKAGLYDVIWQAFAVLLPVRSVGVMGDGRT
YDYVVGLRAVTSTDGMTADFYPFEMSFLGATATRIINEVKGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-134 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-134 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-134 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-121 52