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Name : clpB (Erum6400) Accession : YP_180504.1 Strain : Ehrlichia ruminantium Welgevonden Genome accession: NC_005295 Putative virulence/resistance : Virulence Product : ClpA-type chaperone Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 1074846 - 1077425 bp Length : 2580 bp Strand : - Note : clpB | heat shock protein ClpB | len: 859 aa | Highly similar to many e.g. CLPB_ECOLI P03815 ClpB protein (Heat shock protein F84.1) (857 aa) from Escherichia coli, fasta scores: E(): 7.5e-156, 55.064% identity in 859 aa overlap | Contains 2 Pfam matches DNA sequence : ATGGATTTAAATAAATTTACTGATATATCAAAGAATTTCATAGTGCAAGCGCAAACTTCAGCTGTTGCATTAGGGCATCA GTCTTTAGTACCTGAGCATTTACTTAAGGTAATGTTGGATGATAAAGATGAGATAGTTGAAGTTTTGCTTACTTCTTGTG GGTGTAATGTAGAGACGTTACGTAATGATGTTATATCGGCTTTAAATAAATTACCAGTTGTAAGTGGTCCAGGTAGTGGT CATATACATTTATCAAAGGAAATGGCGCAAGTTTTACAAGAGGCTGTTAATCTTGCAAAAAGACATCAGGACTCTTATGT TACTGTTGAAAGATTACTGCAAGCTCTGACAATAATAAAGGACAGTAATGTTTCTAGGATATTAATTGCACATGGTGTGA CTCCTCAGAAGTTGGAGTCATTAATAGTAAACATGCGTAATGGTGCTAGAGCTGATAGTGTAAATTCTGAGCAAAAGTTT AATGCACTAAAAAAATATGCTAAAGATGTGACTGAAGTTGCTAGAGCAGGAAAATTAGATCCAGTAATTGGAAGAGATGA GGAAATTAGACGTACAATACAGGTATTATTGAGAAGAACAAAAAATAATCCTGTATTAATTGGAGAGCCTGGTGTTGGTA AAACAGCAATTATTGAAGGGTTAGCACATAAGATAGTGAAGGGAGATGTTCCAATTGGGTTGCGAGATATGAGAATAATG TCATTAGATCTTGGTATGCTTGTTGCTGGGACTAAATATAGAGGTGAATTTGAAGAAAGGTTGAAAGCTGTAGTTAATGA AATTGTTTCTTCAAATGGTAGTATTATATTATTCATTGATGAGTTACATACATTAGTTGGTGCTGGTGCAACAGATGGAG CAATGGATGCATCAAATTTGTTGAAGCCAGCATTAGCTAGAGGTGAAATACATTGTATAGGTGCAACAACATTGGATGAA TATAGAAAGCATATAGAAAAAGATGTAGCACTTGCTAGAAGATTTCAAACTATATTTATTTCTGAGCCAACTTGTGATGA TACAATTTCTATGTTACGTGGGTTAAAGGAAAGATATGAAGGACATCATGGTATAGATATTCCTGACAGATCGATAATTG CTGCTGTAGCTTTATCGCAGCGTTATATTACGGATAGGTATTTACCAGATAAAGCTATAGACCTTATTGATGAAGCAGCG AGTCGTGCGAGAATGGAGATTGATAGTAAACCTGAGGTTATTGATAAGTTAGATAGAAAGATAATGCAGCTAAAAATCGA GATAGGAGTATTAGAAAAAGAAAGTGATGAATCCTCAAAACAGAGGTTAATGAAGTTAAAAGATGAACTAGAAAAACTAA ATGTTCAGTCTGCTGAGCTAAGTAGTAAATGGCAAGCGGAAAAAATGAAAATGTCAAAGATGAAAGCATGTAAGGAAAAG CTTGATATTGCTAGAAGTGATTTAGAAAGAGCACAAAGATCTGGTGATTTGGCAAAAGCTGGTGAGTTAATGTATGGTGT AATACCAGAAATTGAGAAAGAGTTAAAAGAACATGAAAAATTTACAAGTAGCCTTTTTAAGAAGGAAATTACAGAACATG ACATAGCAAGTATTGTATCAAAATGGACTGGTATTCCTATTGAGAACATAATGAGTAGTGAAAGAGAAAAACTACTGCGT ATGGAGGAGGAGATAGGCAAAACAGTTATTGGTCAGGATAGTGCTGTAAAAGCAGTAAGTGATGCTGTCAGGAGATCACG TGCAGGGGTACAGGATGCACAGAAACCATTGGGGTCTTTTTTATTTCTTGGGCCAACTGGAGTAGGTAAAACTGAGTTGG TTAAAACATTAGCTGAGTTTTTATTTTGTGATAAGTCTGCACTTTTAAGATTTGACATGTCAGAATTTATGGAAAAGCAT GCTGTTTCACGATTAATAGGAGCTCCTCCAGGATATGTTGGATATGACCAAGGTGGTGCATTAACTGAAGCTGTGAGGAG AAGGCCTTATCAAGTAATATTATTTGATGAAATTGAAAAAGCACATGGAGATATTTTCAATATTTTATTGCAAGTATTAG ATGAAGGAAGATTGACTGATAATCATGGTAAGTTAGTGGATTTCCGTAATACAATACTGGTATTAACTTCAAATTTAGGG CAAGAAATATTAATGAACAATGAATCTGGAAATATCAATGAAGAGTCAGTTAAAGAGTCTGTTACTAATGTGTTGCGTAG TCATTTTCGGCCAGAATTTTTAAATAGATTGGATGAAATTATTATATTTCATAGGTTAACTAAAGAACATATTGAAAGAA TTATTGATGTGCAATTTTCTATATTACAAAAAATTGTTGCTCAAAGAAAATTAGAGATTACTTTATCTTCAGATGCAAAA ACATGGTTGATAAATAATGGCTATGATCCTTTATATGGGGCAAGACCTTTAAAGAGGTTAATACAACAGCAAATACAGAA TAACTTGGCAAAATTAATACTTGCTAATCAGGTAGCTGAAGGTAATAAATTAAGGGTAGATTTATTAGATGATAATCTTG TTATTCATAAGATTAGTTAA Protein sequence : MDLNKFTDISKNFIVQAQTSAVALGHQSLVPEHLLKVMLDDKDEIVEVLLTSCGCNVETLRNDVISALNKLPVVSGPGSG HIHLSKEMAQVLQEAVNLAKRHQDSYVTVERLLQALTIIKDSNVSRILIAHGVTPQKLESLIVNMRNGARADSVNSEQKF NALKKYAKDVTEVARAGKLDPVIGRDEEIRRTIQVLLRRTKNNPVLIGEPGVGKTAIIEGLAHKIVKGDVPIGLRDMRIM SLDLGMLVAGTKYRGEFEERLKAVVNEIVSSNGSIILFIDELHTLVGAGATDGAMDASNLLKPALARGEIHCIGATTLDE YRKHIEKDVALARRFQTIFISEPTCDDTISMLRGLKERYEGHHGIDIPDRSIIAAVALSQRYITDRYLPDKAIDLIDEAA SRARMEIDSKPEVIDKLDRKIMQLKIEIGVLEKESDESSKQRLMKLKDELEKLNVQSAELSSKWQAEKMKMSKMKACKEK LDIARSDLERAQRSGDLAKAGELMYGVIPEIEKELKEHEKFTSSLFKKEITEHDIASIVSKWTGIPIENIMSSEREKLLR MEEEIGKTVIGQDSAVKAVSDAVRRSRAGVQDAQKPLGSFLFLGPTGVGKTELVKTLAEFLFCDKSALLRFDMSEFMEKH AVSRLIGAPPGYVGYDQGGALTEAVRRRPYQVILFDEIEKAHGDIFNILLQVLDEGRLTDNHGKLVDFRNTILVLTSNLG QEILMNNESGNINEESVKESVTNVLRSHFRPEFLNRLDEIIIFHRLTKEHIERIIDVQFSILQKIVAQRKLEITLSSDAK TWLINNGYDPLYGARPLKRLIQQQIQNNLAKLILANQVAEGNKLRVDLLDDNLVIHKIS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 1e-172 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_180504.1 | ClpA-type chaperone | VFG2076 | Protein | 3e-112 | 41 |
