Gene Information

Name : purA (Erum5630)
Accession : YP_180426.1
Strain : Ehrlichia ruminantium Welgevonden
Genome accession: NC_005295
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 969382 - 970674 bp
Length : 1293 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGACAAATATAGTAGTTGTAGGATTACAATGGGGTGACGAAGGTAAGGGAAAAGTTGTAGATTGGTTATCTAATAATGC
AGATGCCGTAGTTAGATTTCAAGGAGGCAATAATGCAGGTCATACTATAGTAATACAAGAGAAAACTTATAAATTAAATT
TACTACCTTCTTCTATTTTACACAATAACAAATTATCAATAATAGGTAATGGGGTTGTCCTAGATCCTTACGCTCTGATG
TCCGAAATTGACAACTTAAGAATCAACGGAATTAATATTAACACTCAAAATCTTGTAATATCAGAATCTTGTCCTTTAGT
ACTCAATATACATAAAGAAGCGGACACGTTATTTGAACAACTAAGACAAAATACTATAGGTACCACAAATAAAGGAATTG
GTCCATGTTACGCCGATAAGATCAGTAGAAGAGCTCTTAGAGTATGTGACCTATTTGATAAAAAAGACATATTGTACAAT
AAGGTCAATAACCTTTTAAATTACCATAATCTATTAAGACAAAATTTTAATATTCTACCAATAGAAGCAAGCAAGTTAGT
AGATGAGCTTTTAGATATCGCACCAAAAATATTACCATTTGTTAAACCTGTATGGAAAGTCATTCATGATCTAACACAAC
AAAATAAAACAATAATCTTTGAAGGAGCCCAAGGTACCTTTTTAGATATTGATCATGGAACATATCCTTTTGTAACATCA
AGTAATACTATAGCACCACAAGCATTTGTTGGAGGAGGTATTAATCTATCACATAGTTCTTGTGTTCTAGGAGTAATAAA
AGCATATACAACACGAGTAGGAAATGGCCCATTCTTTACTGAACAAAAGAATGAAATAGGTAAGTCTATGTTTGAACGAG
GTAATGAAATAGGAACAGTAAGCAATAGAGAAAGAAGATGTGGATGGTTTGATGCCGTATTAGCAAAACAAGCAATCATA
TTATCTGGCGTTTCAGGTCTAGTCTTAACTAAGCTCGATGTATTAGATCAGTTTAGTGAAATAAAAATATGCACACAATA
CAAATATGATGGTGTAATATACGATTACATTCCAGCATCATCTTATGTACAAAATAATTTAGAACCAATTTATGAAACAG
TTCCTGGATGGAAAGAAAATACATTTGGCAGTGTTACATATGAAGACCTACCTAAAAATGCAATATCTTACATAAAAAAA
ATAGAAGAAATCTTAAAAGTACCAGTGTATTTGATATCTACAGGACCAGAAAGGAATGCCATGATTATCATTAACGACAA
GTTCCTTAAATAG

Protein sequence :
MTNIVVVGLQWGDEGKGKVVDWLSNNADAVVRFQGGNNAGHTIVIQEKTYKLNLLPSSILHNNKLSIIGNGVVLDPYALM
SEIDNLRINGININTQNLVISESCPLVLNIHKEADTLFEQLRQNTIGTTNKGIGPCYADKISRRALRVCDLFDKKDILYN
KVNNLLNYHNLLRQNFNILPIEASKLVDELLDIAPKILPFVKPVWKVIHDLTQQNKTIIFEGAQGTFLDIDHGTYPFVTS
SNTIAPQAFVGGGINLSHSSCVLGVIKAYTTRVGNGPFFTEQKNEIGKSMFERGNEIGTVSNRERRCGWFDAVLAKQAII
LSGVSGLVLTKLDVLDQFSEIKICTQYKYDGVIYDYIPASSYVQNNLEPIYETVPGWKENTFGSVTYEDLPKNAISYIKK
IEEILKVPVYLISTGPERNAMIIINDKFLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 8e-79 43