Gene Information

Name : trxB (Erum3470)
Accession : YP_180211.1
Strain : Ehrlichia ruminantium Welgevonden
Genome accession: NC_005295
Putative virulence/resistance : Unknown
Product : thioredoxin reductase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0492
EC number : 1.8.1.9
Position : 602550 - 603506 bp
Length : 957 bp
Strand : -
Note : trxB | thioredoxin reductase | len: 318 aa | Highly similar to many e.g. TRXB_ECOLI P09625 Thioredoxin reductase (320 aa) from Escherichia coli, fasta scores: E(): 7.6e-51, 50.949% identity in 316 aa overlap | Contains Pfam match to PF00070 pyr_redox, Pyr

DNA sequence :
ATGACACAAATATATAAAACTCAAGTTTTAATTTTAGGATCTGGAGCAGCAGGATGTACTGCTGCTATATATGCTGCGCG
TGCAAATTTACAACCCATATTAATTACGGGAATGTGCCCTGGAGGTCAACTCACAATTACTACAGATGTAGAAAATTTTC
CAGGATTTGCACATGCAGTACAAGGTCCAAATCTTATGGAACAAATGCAACAACAAGCTTATAACTCTGGAGCTAAAATT
ATCTCTGATGAAATTAAAGAAATACGTACAGACATGTATCCATTTGAATGTATAGGAATATTTGATGATCATTACATTGC
AAATAGTATAATTATTGCTACAGGAGCTCAAGCAAAGTGGCTAAATATAGAAAGCGAAGAAGCTTTTAAAGGTAAGGGAG
TTTCAGCATGTGCTACATGTGATGGAGTTTTTTTTAGCGGAAGTGATGTTGCTGTAGTAGGAGGAGGTAATACTGCTGTA
GAAGAAGCACTATATTTAACCAGACATGCAACAAAAGTATTCTTAATACACAGACGTGATAAATTACGTGCTGAACCCAT
ACTACAAAAAAGGTTATTCAGTAATGACAAAATACAAGTTATATGGAACAGTAGTGTTAAAGAAATACTAGGTAATAAAG
AAAATGGCACTGTTGAAAAAGTAATATTAGAATCTACAAACACTGGAAATACTACTACTCTTCCAGTAAAAGGAGTGTTT
ATTGCTATAGGACATGCTCCAAATACTAAGATTCTAAAGAAACCAGATAATACAAATATAGTAAGTCTAGATGATGAAGG
ATATATTATTACTAATCCAAATAGCACAGTAACTAGTTGTCCAGGAATTTTTGCTGCAGGTGATGTACAAGATAAAATAT
ATAGGCAGGCTGTTGTTGCAGCAGGTTCAGGGTGTATGGCAGCAATAGAAGCTGCAAAGTTTCTTTCTGACAACTAA

Protein sequence :
MTQIYKTQVLILGSGAAGCTAAIYAARANLQPILITGMCPGGQLTITTDVENFPGFAHAVQGPNLMEQMQQQAYNSGAKI
ISDEIKEIRTDMYPFECIGIFDDHYIANSIIIATGAQAKWLNIESEEAFKGKGVSACATCDGVFFSGSDVAVVGGGNTAV
EEALYLTRHATKVFLIHRRDKLRAEPILQKRLFSNDKIQVIWNSSVKEILGNKENGTVEKVILESTNTGNTTTLPVKGVF
IAIGHAPNTKILKKPDNTNIVSLDDEGYIITNPNSTVTSCPGIFAAGDVQDKIYRQAVVAAGSGCMAAIEAAKFLSDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trxB CAJ77014.1 thioredoxin reductase Not tested AbaR1 Protein 2e-59 51
trxB AFC76431.1 TrxB Not tested AbaR5 Protein 3e-59 51