Gene Information

Name : VVA1306 (VVA1306)
Accession : NP_937362.1
Strain :
Genome accession: NC_005140
Putative virulence/resistance : Virulence
Product : vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1444540 - 1446168 bp
Length : 1629 bp
Strand : -
Note : -

DNA sequence : 
ATGGTCGTCGCGACAACCGAAACACCAAAGCAGATACTCGATGGCTTTGTGCGTAAACCTAGTGTTCAAAGTGAACAATA
TCAGGCTGCAAATTTGTGGCGCAATTTGCCGCTGTGGCAAATTCTTCATCAGGGAGTAGGGCGTCACCCAGATAGGATAG
CGGTGACCGATAACCACACTTCGCTGAGCTATCTCGAGTTGGCCAATCATGTGGATAGGATCGCCGCTGGGTTGAGAGAA
GAAGGGCTTGTGTGTGGTGACAGTGTTGTCTTGCAGTTAGCCAATACACTCGATTTTCTCGTCGTGTTTTTTGCTCTTCA
GCGCCTTGGTGTGGTTCCCGTACTGGCATTACCTGCACACGGTTTGGTCGAAATTCGCCACTTTATGCAACTCTCTGGGG
CAAGAGTGTACATCGGCTCCAATCATGAAAAGGATGACAAAGCGTTGGCGATTGCCACTCAGTTGCAAGCGGAACTATCA
ATATCCATTCGCTGCTATATCTGCGGGCATTTTGGTCAGTTTTCGCCGTTGCCAGAGTGTGACGCTGGCGATTTTGCACC
AGCGATGGTAGACCCAGAACACCCGGCACTTTTCCTCGTTTCTGGAGGCACGACAGGGCTACCCAAACTGATCCCCCGTA
CCCACAATGATTATCTGTTTAATGTTGAGCAATGTGCGAAAGCCAGTGAAATCAGTGCGCAGGATGTGTATTTGGCGGTG
TTGCCTGCGGCACACAATTTTACCTTGGGTTGTCCTGGGATCTTAGGGGTGTTGAATACTGGCGGAAAAGTGGTTTTGAC
CACCAACCCAAGCCCAGATTATTGTTTTGAACTTATTGAAAAACAGCGTATTACCGCAACGGCGTTGGTGCCTGCATTGG
CGCAGCTGTGGACGGAGGCAACTCAATGGGAGTCGACGGATCGTTCGAGTTTACGTTTGATGCAAGTCGGTGGTTCCAAA
CTTGCTTATAGCGATGCGCTGGAAATGCAAAACGCCTTTCCAAACGCGTTGCAGCAAGTTTTTGGTATGGCGGAAGGTTT
GATTGCGTGTACCCGTTTGGGCGATGACAAAGAAATTATTGCAACAAGGCAAGGTCGTCCTGTCAGCGAATGGGACGAGG
TCCTCGTTGTGGATGATCAAGGCAAGCCAGTTGCGGTTGGAGAGGAAGGGGAACTGCTGACCCGAGGGCCTTACACGCTT
AGCGGATATTACCGTGCGCCAGAGCATAATCTGCGGGCGTTTACGGATGAAGGATATTATCGCAGTGGCGATCGCGTGGT
CGTCGATTCCCAAGGTTACTTCACGGTCACTGGGCGGATAAAGGATGTGATCATTCGTGCTGGCGAAAACATTGCTGCTG
ATGAGTTAGAAGAGCTCTTATTGTCGCATCCACAAATTGCCCAAGTAGCGGTGTTTCCCCTGCCAGATGCTCATTTAGGT
GAAAAAATCGCCGTCGCCGCCGTCATTCGAGGTCCCGAAATTATGTTGCGTGATATTCGGCAATTTCTCCAAGCCAAAGA
GATCGCCGCATTCAAACTTCCTGATGAACTCTTTGCGGTCAAATCGTTGCCAAAAACGGCCGTAGGCAAAATCGACAAGA
AGCGCATTTTAAGCACCATTCTGCCGTGA

Protein sequence : 
MVVATTETPKQILDGFVRKPSVQSEQYQAANLWRNLPLWQILHQGVGRHPDRIAVTDNHTSLSYLELANHVDRIAAGLRE
EGLVCGDSVVLQLANTLDFLVVFFALQRLGVVPVLALPAHGLVEIRHFMQLSGARVYIGSNHEKDDKALAIATQLQAELS
ISIRCYICGHFGQFSPLPECDAGDFAPAMVDPEHPALFLVSGGTTGLPKLIPRTHNDYLFNVEQCAKASEISAQDVYLAV
LPAAHNFTLGCPGILGVLNTGGKVVLTTNPSPDYCFELIEKQRITATALVPALAQLWTEATQWESTDRSSLRLMQVGGSK
LAYSDALEMQNAFPNALQQVFGMAEGLIACTRLGDDKEIIATRQGRPVSEWDEVLVVDDQGKPVAVGEEGELLTRGPYTL
SGYYRAPEHNLRAFTDEGYYRSGDRVVVDSQGYFTVTGRIKDVIIRAGENIAADELEELLLSHPQIAQVAVFPLPDAHLG
EKIAVAAVIRGPEIMLRDIRQFLQAKEIAAFKLPDELFAVKSLPKTAVGKIDKKRILSTILP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 9e-93 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-93 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 9e-93 46
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-93 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-93 46
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-93 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-93 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-91 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-91 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VVA1306 NP_937362.1 vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-104 47
VVA1306 NP_937362.1 vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 5e-103 46
VVA1306 NP_937362.1 vulnibactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-89 41